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The Cost-effectiveness Of Early Resuscitation Of Sepsis In Australia - An Economic Evaluation Alongside The ARISE-RCT
Funder
National Health and Medical Research Council
Funding Amount
$115,971.00
Summary
Critical care treatment is expensive and consumes a significant portion of hospital resources. This study will collect cost, survival and quality of life data on a group of sepsis patients enrolled in a trial of strict protocolised treatment versus standard care (the ARISE study). This information will be used to determine how much it costs for each additional survivor with protocolised treatment, and how much it costs for each quality adjusted life year gained with protocolised treatment.
Pathogenesis Of Vascular Shock And Platelet Dysfunction In Sepsis: The Role Of Calcium Desensitization, Statins And Cortisol.
Funder
National Health and Medical Research Council
Funding Amount
$89,778.00
Summary
Severe infections are characterised by a profound drop in blood pressure, which starve vital organs of oxygen and nutrients, this �septic shock� can lead to organ failure and death. We aim to identify dysfunction of the molecular signals in blood vessels, which leads to the failure of these vessels to maintain adequate blood pressure. Understanding the mechanisms regulating blood pressure during septic shock will enable us to develop therapies to support the circulation and reduce the significan ....Severe infections are characterised by a profound drop in blood pressure, which starve vital organs of oxygen and nutrients, this �septic shock� can lead to organ failure and death. We aim to identify dysfunction of the molecular signals in blood vessels, which leads to the failure of these vessels to maintain adequate blood pressure. Understanding the mechanisms regulating blood pressure during septic shock will enable us to develop therapies to support the circulation and reduce the significant death toll from life threatening sepsis.Read moreRead less
Improving Patient Outcomes Through Understanding And Changing Transfusion Practice
Funder
National Health and Medical Research Council
Funding Amount
$75,347.00
Summary
Blood transfusion has a central role in many areas of clinical medicine. Despite its widespread use, there are large areas where evidence to inform clinical practice is limited. The aim of this proposed research is to investigate the current use of blood products in clinical medicine. Data on blood transfusion will be linked with existing clinical registries to examine how transfusion practice influences patient outcomes in a range of clinical areas including trauma, surgery and critical care.
Examining The Interface Between Complementary And Alternative Medicine Use And Provision And Rural General Practice.
Funder
National Health and Medical Research Council
Funding Amount
$85,580.00
Summary
The project aims to improve rural health outcomes by investigating practices and perspectives of rural general practitioners (GPs) regarding complementary medicine (CAM). CAM use is highest in rural areas and this could have potential safety issues when combined with conventional healthcare. The results will better equip rural health providers coordinate and manage healthcare for their patients, avoid potential complications and give rural GPs a perspective on managing challenges posed by CAM.