A novel reversible male sterility system for hybrid seed production in canola, cotton and oilseed mustard. Demand for grains, fibre and other agricultural products has recently increased significantly. Hence, the security of food production is emerging as a critical global issue. We have identified a central component (AtMYB103) controlling tapetum and thus pollen development and designed a novel reversible male sterility system using AtMYB103. The efficient hybrid seed production systems develo ....A novel reversible male sterility system for hybrid seed production in canola, cotton and oilseed mustard. Demand for grains, fibre and other agricultural products has recently increased significantly. Hence, the security of food production is emerging as a critical global issue. We have identified a central component (AtMYB103) controlling tapetum and thus pollen development and designed a novel reversible male sterility system using AtMYB103. The efficient hybrid seed production systems developed in this project for canola, cotton and mustard will increase the productivity of the Australian oilseed and fibre industries. AtMYB103 gene is conserved among many crop plants. Hence, the new technologies and knowledge gained will be applicable to a wide range of crop plants and have important implications for the agricultural and food industries.Read moreRead less
Functional analysis of Bacillus thuringiensis crystal toxins. Pore-forming toxins, such as anthrax, hemolysin, cholera and diphtheria toxins, are among the most virulent microbial toxins, posing a threat to humans and lifestock. We are using a novel functional approach to test possible lectin and antimicrobial peptide functions of a typical and economically important pore-forming toxin, the crystal endotoxin from Bacillus thuringiensis, to examine why toxicity of the lectin-containing toxin is ....Functional analysis of Bacillus thuringiensis crystal toxins. Pore-forming toxins, such as anthrax, hemolysin, cholera and diphtheria toxins, are among the most virulent microbial toxins, posing a threat to humans and lifestock. We are using a novel functional approach to test possible lectin and antimicrobial peptide functions of a typical and economically important pore-forming toxin, the crystal endotoxin from Bacillus thuringiensis, to examine why toxicity of the lectin-containing toxin is restricted to invertebrates only, while the amphipathic peptide alone is also toxic to many vertebrate cells. The outcome of these experiments has important implications for the sustainable use of biopesticides and for the prevention and containment of infectious diseases.Read moreRead less
Development of eco-friendly alternatives for crop pest management. This project will produce novel insecticides to protect cotton and other crops from a range of economically damaging pests. It will lead to a more sustainable and eco-friendly cotton industry by reducing the dependence on chemical insecticides and genetically modified cotton plants.
Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack. The aim of this project is to characterise the interactions between various known plant proteinase inhibitors and the major digestive enzymes of insects by structural and dynamic studies and to utilise mutational studies to design new inhibitors that more effectively bind to target proteinases. The outcomes will be the knowledge to design specific inhibitors to give optimal inhibition of specific ....Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack. The aim of this project is to characterise the interactions between various known plant proteinase inhibitors and the major digestive enzymes of insects by structural and dynamic studies and to utilise mutational studies to design new inhibitors that more effectively bind to target proteinases. The outcomes will be the knowledge to design specific inhibitors to give optimal inhibition of specific insect proteinases. This knowledge will lead to novel approaches to protect economically important crops, such as cotton, from insect pests in Australia - potentially saving tens of millions of dollars per annum in chemical pesticide use and enhancing crop production in Australia and internationally.Read moreRead less