A soil ecological approach to increasing Australian crop productivity. The objective of this project is to use emerging genomics technologies to identify and characterize soil bacteria that allow the replacement of current agricultural fertilisers, which have significant environmental and economic disadvantages, with sustainable biological fertilisers. Soil bacteria can greatly enhance phosphate solubilization and hence availability for plant growth. Beneficial microbes will be identified from o ....A soil ecological approach to increasing Australian crop productivity. The objective of this project is to use emerging genomics technologies to identify and characterize soil bacteria that allow the replacement of current agricultural fertilisers, which have significant environmental and economic disadvantages, with sustainable biological fertilisers. Soil bacteria can greatly enhance phosphate solubilization and hence availability for plant growth. Beneficial microbes will be identified from our existing soil collection and their performance and persistence optimised. Concurrently, our industry partners will develop suitable microbial formulations for application. The outcomes of the project will be the use of biological fertilisers to enhance crop productivity in an environmentally sustainable manner.Read moreRead less
Functional analysis of Bacillus thuringiensis crystal toxins. Pore-forming toxins, such as anthrax, hemolysin, cholera and diphtheria toxins, are among the most virulent microbial toxins, posing a threat to humans and lifestock. We are using a novel functional approach to test possible lectin and antimicrobial peptide functions of a typical and economically important pore-forming toxin, the crystal endotoxin from Bacillus thuringiensis, to examine why toxicity of the lectin-containing toxin is ....Functional analysis of Bacillus thuringiensis crystal toxins. Pore-forming toxins, such as anthrax, hemolysin, cholera and diphtheria toxins, are among the most virulent microbial toxins, posing a threat to humans and lifestock. We are using a novel functional approach to test possible lectin and antimicrobial peptide functions of a typical and economically important pore-forming toxin, the crystal endotoxin from Bacillus thuringiensis, to examine why toxicity of the lectin-containing toxin is restricted to invertebrates only, while the amphipathic peptide alone is also toxic to many vertebrate cells. The outcome of these experiments has important implications for the sustainable use of biopesticides and for the prevention and containment of infectious diseases.Read moreRead less