Investigation Of Zinc Dyshomeostasis Associated With Aging And Dementia-related Disorders Using Novel Nanodiamond-based Markers
Funder
National Health and Medical Research Council
Funding Amount
$604,644.00
Summary
This project will illuminate the fundamental brain changes that lead to age-related cognitive decline by means of newly developed biamarker based on fluorescent nanodiamonds. The expected outcome of this work will be a unique approach to elucidate the source of cognitive decline that will fill a significant unmet need within the community.
Enhancing Direct Cu Recovery through Increased Gas Processing Understanding. This project aims to investigate mechanisms of copper loss during smelting and find new ways to reduce the loss. Smelting, which produces copper matte product and slag tailings, is an important step of the copper-making process from copper sulphides. The loss of copper to slag can be as high as 12 per cent. The project aims to create new knowledge about copper loss by matte droplets floated with gas bubbles generated by ....Enhancing Direct Cu Recovery through Increased Gas Processing Understanding. This project aims to investigate mechanisms of copper loss during smelting and find new ways to reduce the loss. Smelting, which produces copper matte product and slag tailings, is an important step of the copper-making process from copper sulphides. The loss of copper to slag can be as high as 12 per cent. The project aims to create new knowledge about copper loss by matte droplets floated with gas bubbles generated by chemical reactions to the slag phase. The outcomes are intended to enable copper smelters to maximise direct copper recovery, reduce copper production costs and increase the productivity of the smelting process.Read moreRead less
The Clinicial Centre Of Research Excellence At The Jean Hailes Foundation: For The Study Of Women's Health
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
The major health issues affecting women from the mid-reproductive years include depression, disorders of mood and sexual function, and breast cancer, with cardiovascular disease, osteoporosis, and osteoarthritis becoming increasingly prevalent with age. Linking each of these are their known or probable causal associations with oestrogens and androgens. This Centre will provide an opportunity for comprehensive and multidisciplinary research into the role of oestrogens and androgens in these disor ....The major health issues affecting women from the mid-reproductive years include depression, disorders of mood and sexual function, and breast cancer, with cardiovascular disease, osteoporosis, and osteoarthritis becoming increasingly prevalent with age. Linking each of these are their known or probable causal associations with oestrogens and androgens. This Centre will provide an opportunity for comprehensive and multidisciplinary research into the role of oestrogens and androgens in these disorders.Read moreRead less
A revolution in Earth History: Life and Environment in the Neoarchaean (2.5-2.8 Ga). This research will keep Australian scientists in the forefront of studies of early life on Earth. At a time when there is a great deal of interest in this topic because of the search for similar life elsewhere in the Solar System, this work will take a prominant place in international research. It will attract leading researchers from elsewhere, with consequent intellectual benefits, and will inspire students t ....A revolution in Earth History: Life and Environment in the Neoarchaean (2.5-2.8 Ga). This research will keep Australian scientists in the forefront of studies of early life on Earth. At a time when there is a great deal of interest in this topic because of the search for similar life elsewhere in the Solar System, this work will take a prominant place in international research. It will attract leading researchers from elsewhere, with consequent intellectual benefits, and will inspire students to careers in science.Read moreRead less
Where to find giant porphyry and epithermal gold and copper deposits. This project will determine when and where giant gold or copper deposits should form, consolidating links with Indonesia, and using South East Asia as a vast natural laboratory in which to examine the effect of large-scale tectonic processes. The project will produce a four-dimensional virtual exploration toolkit to show how to apply the methods.
Carbothermal synthesis of titanium carbide. The project's ultimate aim is to develop a comprehensive understanding of carbothermal reduction of titania and ilmenite for titanium carbide production. The projects findings will be of importance to improving the efficiency of carbothermal reduction processes, which are major technologies in ferrous metallurgy, and to the development of titanium industry in Australia.
Australia is the world largest producer of rutile and ilmenite, which are mainly s ....Carbothermal synthesis of titanium carbide. The project's ultimate aim is to develop a comprehensive understanding of carbothermal reduction of titania and ilmenite for titanium carbide production. The projects findings will be of importance to improving the efficiency of carbothermal reduction processes, which are major technologies in ferrous metallurgy, and to the development of titanium industry in Australia.
Australia is the world largest producer of rutile and ilmenite, which are mainly sold overseas and partly processed to titania pigment. Development of the cost-efficient technology for titanium carbide will stimulate a domestic production of this advanced material, what will add enormously to the value of titanium minerals.Read moreRead less
Utilisation of manganese sludge in production of manganese alloys. Australia possesses one of the world's best deposits of manganese ore, and has the potential to increase production of manganese alloys. This depends strongly on the competitiveness of Australian manganese industry. Deposition of manganese sludge, which is formed in ferroalloy furnaces, in fume dams in Bell Bay is costly, occupies valuable land, and causes an environmental concern. Utilisation of manganese sludge back into ferroa ....Utilisation of manganese sludge in production of manganese alloys. Australia possesses one of the world's best deposits of manganese ore, and has the potential to increase production of manganese alloys. This depends strongly on the competitiveness of Australian manganese industry. Deposition of manganese sludge, which is formed in ferroalloy furnaces, in fume dams in Bell Bay is costly, occupies valuable land, and causes an environmental concern. Utilisation of manganese sludge back into ferroalloy furnace will make operation of Tasmanian Electro Metallurgical Company more efficient, sustainable and will stimulate further development of manganese industry in Australia. Read moreRead less
A study of wettability and reduction behaviour in carbothermal production of manganese alloys. The project's ultimate aim is to develop a comprehensive understanding of reactions between carbonaceous materials and molten slag relevant to carbothermal reduction of manganese ore. It will be achieved through experimental study of dynamic wettability and interfacial properties of the carbon - slag system for variety of carbonaceous materials and slag compositions. Reduction behaviour of different ma ....A study of wettability and reduction behaviour in carbothermal production of manganese alloys. The project's ultimate aim is to develop a comprehensive understanding of reactions between carbonaceous materials and molten slag relevant to carbothermal reduction of manganese ore. It will be achieved through experimental study of dynamic wettability and interfacial properties of the carbon - slag system for variety of carbonaceous materials and slag compositions. Reduction behaviour of different manganese ores will also be examined in conjunction with the wettability study. The projects findings will be of importance to carbothermal reduction processes, which are major technologies in ferrous metallurgy, and to further development of the manganese alloys industry in Australia.Read moreRead less
Role Of Transition Metal Ions And Redox Activity In The Development Of Atherosclerotic Plaques
Funder
National Health and Medical Research Council
Funding Amount
$196,018.00
Summary
Metal ions such as iron and copper have been reproted to be present in the lesions present in diseased human arteries and it has been suggested that these metal ions contribute to the development of atherosclerosis (hardening of the arteries) via their ability to catalyse the formation of highly reactive molecualr fragments called free radicals. Though metal ions are known to catalyse such reactions in test-tube experiments, both the presence of metal ions in diseased arteries and their ability ....Metal ions such as iron and copper have been reproted to be present in the lesions present in diseased human arteries and it has been suggested that these metal ions contribute to the development of atherosclerosis (hardening of the arteries) via their ability to catalyse the formation of highly reactive molecualr fragments called free radicals. Though metal ions are known to catalyse such reactions in test-tube experiments, both the presence of metal ions in diseased arteries and their ability to generate free radicals is controversial. This study will employ a novel, minimally-invasive, technique to assess the nature and quantity of metal ions present in well-defined human and animal lesions at different stages of lesion development. The ability of these metal ions to catalyse free radical formation from components present in the artery wall will also be assessed. The release of these metal ions from the artery wall to added organic molecules will be assessed as this might minimise their potential to cause damage, and provide a possible therapeutic strategy. These studies will therefore provide valuable information as to the significance and role of reactive metal ions in the development of human artery disease and the possible prevention, or minimisation, of such processes.Read moreRead less
Characterisation of carbonaceous materials in production of manganese alloys. Optimisation of the carbonaceous materials feedstock in production of manganese alloys will increase energy efficiency and decrease environmental impact in operation of submerged electric arc furnace. Currently, Australia processes domestically only about 25% of produced manganese ore, while 75% is sold as raw material. Increase in production of manganese alloys will add value to the products and create additional empl ....Characterisation of carbonaceous materials in production of manganese alloys. Optimisation of the carbonaceous materials feedstock in production of manganese alloys will increase energy efficiency and decrease environmental impact in operation of submerged electric arc furnace. Currently, Australia processes domestically only about 25% of produced manganese ore, while 75% is sold as raw material. Increase in production of manganese alloys will add value to the products and create additional employment opportunities, what will be beneficial to the Australian economy. The project will also contribute to further understanding of behaviour of coals in pyrometallurgical processes what will be beneficial to coal industry.Read moreRead less