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Engineering drug transportation behaviour in polymeric gel systems. In collaboration with Seagull Technologies, this project aims to engineer, study and mathematically model ultrasound-assisted biomacromolecule transport behaviour within polymeric gel systems, which may be useful in new drug delivery methods. The intended outcome is a novel set of polymeric gel systems, which can reversibly bind a wide variety of drugs (small molecules, nucleic acid based drugs, proteins), in which drug release ....Engineering drug transportation behaviour in polymeric gel systems. In collaboration with Seagull Technologies, this project aims to engineer, study and mathematically model ultrasound-assisted biomacromolecule transport behaviour within polymeric gel systems, which may be useful in new drug delivery methods. The intended outcome is a novel set of polymeric gel systems, which can reversibly bind a wide variety of drugs (small molecules, nucleic acid based drugs, proteins), in which drug release is triggered by an electric potential and drug transport is controlled by means of sonophoresis. The main advantage of drug delivery via sonophoresis is elimination of risks associated with injections such as infection and damage to local tissue, and elimination of patient discomfort, pain and fear.Read moreRead less
Macromolecular Engineering of Functional Metal–Ligand Materials. Materials self-assembled from metal ions and ligands have a range of important applications, including as advanced coatings, adhesives and catalysts. However, these materials have been largely limited to those assembled from naturally occurring ligands such as phenolics, restricting their properties and function. This project aims to greatly expand the range of accessible properties of metal–phenolic materials by combining self-ass ....Macromolecular Engineering of Functional Metal–Ligand Materials. Materials self-assembled from metal ions and ligands have a range of important applications, including as advanced coatings, adhesives and catalysts. However, these materials have been largely limited to those assembled from naturally occurring ligands such as phenolics, restricting their properties and function. This project aims to greatly expand the range of accessible properties of metal–phenolic materials by combining self-assembly with advanced polymer synthesis techniques. The expected outcome of the project is a new class of functional materials applicable as self-healing coatings, nanoadhesives and antimicrobial surfaces, thus underpinning next-generation technologies in materials science and nanotechnology.Read moreRead less
Smart materials from semi-soft particles. This project will combine precision polymer chemistry to material science to develop structured nanoparticles for applications in photonics and shape memory materials.
Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The exp ....Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The expected outcomes include new methods, models and a workable map of protein adsorption allowing us to 1) create advanced substrates for targeted applications and 2) understand existing phenomenon governed by naturally occurring nanoroughness. It will benefit manufacturing in fields ranging from biology to energy production.Read moreRead less
ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resultin ....ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resulting technology breakthroughs will have a direct impact on some of today's most challenging global problems in clean energy, synthetic biosystems, diagnostics and soft robotics. National benefit to Australia will be realised through the creation of new manufacturing industries.Read moreRead less
Next-generation lithography: photo-directing assembly of block copolymers. This project aims to introduce a novel approach to organising block polymers through the photochemical modification of the surface of a photo-sensitive polymer. Chemo-epitaxy is the science of organising materials on a surface decorated with chemical patterns. The process has the potential to revolutionise the manufacture of integrated circuits, enabling faster processors. This project expects to introduce innovative conc ....Next-generation lithography: photo-directing assembly of block copolymers. This project aims to introduce a novel approach to organising block polymers through the photochemical modification of the surface of a photo-sensitive polymer. Chemo-epitaxy is the science of organising materials on a surface decorated with chemical patterns. The process has the potential to revolutionise the manufacture of integrated circuits, enabling faster processors. This project expects to introduce innovative concepts in polymer chemistry and nanoscale assembly with the potential to advance a multi-billion-dollar industry.Read moreRead less
Advanced bio-inspired polymer assembly: tools for diagnostics, imaging and therapies. ‘Smart’ polymeric materials have the potential to make a significant impact in areas such as healthcare. However, to do this effectively the materials will need to respond intelligently to biological signals. This project will involve the synthesis and application of ‘smart’ polymer films and particles, which mimic biological behaviour.
Organic-inorganic hybrids via a combination of ring opening metathesis polymerisation, Thiol-Ene Click chemistry and Sol-Gel reactions. The research aims to develop a fast and efficient process for the preparation of advanced organic-inorganic materials. The successful completion of this research will yield new materials that may be exploited in advanced specialty applications including in biomedical and fuel cell areas.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100035
Funder
Australian Research Council
Funding Amount
$370,000.00
Summary
Advanced Nanomaterials Characterisation Facility. Advanced nanomaterials characterisation facility:
The integrated facility aims to provide precise characterisation of physicochemical properties of natural and engineered nanoparticles and their interaction with biological matrices. Such information would advance manufacturing, bioengineering, energy production, environmental and forensic science and nanomedicine.
Controlling the organisation of matter using vortex fluidics. Vortex fluidic devices will be developed and used to construct functional complex molecules and materials, and probe the structure of self assembled systems. The scalable processing will be assessed for application in advanced materials production, the chemical industry and in developing complex molecules for drug discovery.