Australian Laureate Fellowships - Grant ID: FL150100146
Funder
Australian Research Council
Funding Amount
$2,977,310.00
Summary
Taking Australia from the farm to the pharm. Taking Australian from the farm to the pharm: This fellowship project aims to design novel drugs based on cyclic peptides that will be expressed in the seeds of plants to produce bio-pills — saving money for patients and the health care system. Plants produce unique cyclic peptides (mini-proteins) to protect themselves from pests and pathogens. This project aims to chemically redesign these peptides to produce stable protein-based pharmaceuticals that ....Taking Australia from the farm to the pharm. Taking Australian from the farm to the pharm: This fellowship project aims to design novel drugs based on cyclic peptides that will be expressed in the seeds of plants to produce bio-pills — saving money for patients and the health care system. Plants produce unique cyclic peptides (mini-proteins) to protect themselves from pests and pathogens. This project aims to chemically redesign these peptides to produce stable protein-based pharmaceuticals that can be eaten. It is hoped that these designer pharmaceuticals will be inexpensive, effective, easy to ingest and without the side effects of traditional drugs. The outcomes of this project are anticipated to be high-value drugs and agri-chemicals which will open up new high-value crops for Australian farmers and a new Australian ‘pharming’ industry.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL0992179
Funder
Australian Research Council
Funding Amount
$2,985,000.00
Summary
Adapting the sustainable exploitation of coral reef resources to provide for climate change. The research program quantifies the impacts of climate change on coral reefs and harnesses remote sensing technology and ecological modelling to provide new tools for reef management. Research outcomes will help bodies such as the Great Barrier Reef Marine Park Authority adapt their management of marine production systems to take account of climate change, and thereby help ensure the sustainable delivery ....Adapting the sustainable exploitation of coral reef resources to provide for climate change. The research program quantifies the impacts of climate change on coral reefs and harnesses remote sensing technology and ecological modelling to provide new tools for reef management. Research outcomes will help bodies such as the Great Barrier Reef Marine Park Authority adapt their management of marine production systems to take account of climate change, and thereby help ensure the sustainable delivery of ecosystem services including tourism, recreation, fisheries, and the sustainability of Australia's marine biodiversity. Algorithms generated by the study will also help resource managers better target their actions, which improves both conservation benefits and value for money.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100109
Funder
Australian Research Council
Funding Amount
$2,762,247.00
Summary
Unifying mechanisms of innate immunity signaling in animals and plants. This project aims to improve our understanding of innate immunity, the first line of defense against pathogens in diverse organisms. Innate immune pathways are key to a range of pathological states in animals, and provide plants with resistance to the diseases that account for 15% of crop losses. This project will generate knowledge, through characterising mechanisms of cell signalling for mammalian and plant innate immunity ....Unifying mechanisms of innate immunity signaling in animals and plants. This project aims to improve our understanding of innate immunity, the first line of defense against pathogens in diverse organisms. Innate immune pathways are key to a range of pathological states in animals, and provide plants with resistance to the diseases that account for 15% of crop losses. This project will generate knowledge, through characterising mechanisms of cell signalling for mammalian and plant innate immunity. The outcomes will include a unified signalling model, and form the foundation for a range of applications in human biology and agriculture, such as the development of durable and effective resistance in crops.Read moreRead less