Cross-comparison, Validation And Performance Of Computerised Neuropsychological Assessment Devices In The Evaluation Of Mild Cognitive Impairment And Dementia
Funder
National Health and Medical Research Council
Funding Amount
$700,482.00
Summary
With an ageing population and associated increase in dementia there will be increased demand for neuropsychological assessment, with insufficient trained personnel and resources to meet this demand. Computerised tests offer excellent opportunities for large scale implementation of cognitive screening and monitoring of older adults. This is the first study to systematically evaluate and compare several popular computerised neuropsychological assessment devices in elders with and without dementia.
Improving Evidence Based Care For Locally Advanced Prostate Cancer
Funder
National Health and Medical Research Council
Funding Amount
$533,442.00
Summary
There is an urgent need to improve care for men with advanced prostate cancer if we wish to improve their survival. Compelling new evidence suggests we need to alter current practice by offering radiotherapy to high risk men – but will clinicians change their practice? We will develop and test ways to change practice within a network of 9 hopsitals. The study will provide crucial evidence about how to embed the recommended care into practice to improve outcomes for men with prostate cancer.
Media Formulations To Enhance Embryo Formation In Assisted Reproduction
Funder
National Health and Medical Research Council
Funding Amount
$660,133.00
Summary
The increasing age of parenthood has led to an explosion in the demand for assisted reproductive technologies such as in vitro fertilisation (IVF). This procedure has a poor success rate and is limited by the ability of fertilised eggs to mature into early embryos in the lab prior to being transferred into women. We will develop new compounds that improve embryo growth in the clinic, which will improve IVF success rates.
Nicotinamide Adenine Dinucleotide (NAD+)-raising Agents For Improving Oocyte Quality
Funder
National Health and Medical Research Council
Funding Amount
$445,827.00
Summary
Many women cannot have children because of suboptimal egg quality, often due to aging. Currently, the only option is to use better quality eggs donated from another woman. This project will use pharmacological agents to promote recently discovered pathways in eggs central to determining quality. Importantly, we will investigate a simple and practical approach that can be used in clinics for augmenting these pathways to improve oocyte quality for the first time.
A Cluster Randomised Controlled Trial Of Nurse And General Practitioner Partnership For Care Of COPD
Funder
National Health and Medical Research Council
Funding Amount
$449,377.00
Summary
Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease that can progress to severe disability and use of hospital services. It is an important cause of both death and disability in Australia. Specifically it is the third leading cause of disease burden after heart disease and stroke. Smoking is the most important cause of the disease and there is strong evidence that smoking cessation will largely prevent progression of COPD. National evidence based guidelines for management of COPD w ....Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease that can progress to severe disability and use of hospital services. It is an important cause of both death and disability in Australia. Specifically it is the third leading cause of disease burden after heart disease and stroke. Smoking is the most important cause of the disease and there is strong evidence that smoking cessation will largely prevent progression of COPD. National evidence based guidelines for management of COPD were published in 2003 but these need to be implemented in the community. General practice is well placed to have a key role in early intervention and evidence based management of COPD. There is evidence that specialised nurses working in collaboration with GPs can improve the care the chronic illnesses including COPD. Care Plans with input from health professionals from a range of disciplines have been recommended for COPD but there are barriers to implementing these in general practice. This project brings together nurse assistance and care planning in a model of care designed to deliver best practice management of COPD in the community. The aim of this research is to evaluate the impact of anurse and GP partnership for care of COPD. We will examine the effect on quality of care and health outcomes at 6 and 12 months follow up. Our hypothesis is that the use of a nurse to work as a team with the patient and GP to develop and implement a care plan based on clinical practice guidelines will improve the quality of care received and have a beneficial effect on the patients' respiratory and overall health. This research will be of major significance for improving COPD care in the community and will have far reaching implications for both policy and practice. It will also define a new role for nurses and GPs working in partnership.Read moreRead less
Improving Strategies To Support Pregnant Aboriginal Women To Quit Smoking
Funder
National Health and Medical Research Council
Funding Amount
$380,891.00
Summary
The overall objective of this project is to produce new knowledge about effective strategies for decreasing the smoking rates in pregnant Aboriginal women. The studies aim to: 1. Understand pregnant Aboriginal smokers attitudes to and experiences of using quit smoking methods 2. Understand what behaviour change techniques may be useful for pregnant Aboriginal women who smoke 3. Explore clinicians’ knowledge, attitudes and practices of providing behavioural counselling and nicotine replacemen
Implementing Guidelines To Routinely Prevent Chronic Disease In General Practice
Funder
National Health and Medical Research Council
Funding Amount
$764,446.00
Summary
High quality, evidence-based guidelines for preventive activities and for the implementation of prevention in general practice have been developed by the Royal Australian College of General Practitioners and other bodies, yet available information suggests that many patients miss out on evidence-based preventive care. This project aims to evaluate current practice and develop a model of practice aimed at improving the implementation of preventive guidelines in general practice.
Effective software vulnerability detection for web services. This project aims to design and implement new and better methods to find vulnerabilities in software services delivered over the web or through the cloud, as well as methods for proving the absence of certain types of vulnerability. So-called injection attacks are pervasive and generally considered the most important security threat on today's Internet. The programming languages used for software services tend to use strings as a unive ....Effective software vulnerability detection for web services. This project aims to design and implement new and better methods to find vulnerabilities in software services delivered over the web or through the cloud, as well as methods for proving the absence of certain types of vulnerability. So-called injection attacks are pervasive and generally considered the most important security threat on today's Internet. The programming languages used for software services tend to use strings as a universal data structure, which unfortunately makes it hard to separate trusted code from untrusted user-provided data. This project intends to develop novel program analysis tools and string constraint solvers, and employ these tools to support sophisticated automated reasoning about string manipulating software.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347131
Funder
Australian Research Council
Funding Amount
$115,490.00
Summary
Intelligent Computer System to Access Information Directly from the Brain Using High Resolution Electroencephalography and Repetitive Transcranial Magnetic Stimulation. The ambitious aim of this project is to create a novel intelligent computer system which accesss information from the brain. To do this we use repetitive Transcranial Magnetic Stimulation and high resolution Electroencephalography.
Improving Global Tuberculosis Control With The AuTuMN Platform
Funder
National Health and Medical Research Council
Funding Amount
$655,059.00
Summary
Tuberculosis (TB) is the world’s leading infectious killer, with the failure of global control responsible for the vast majority of Australia’s cases. Using our robustly developed software platform, we have performed several country-level studies to predict the future burden of disease and compare the impact of alternative responses to controlling the epidemic. In this project, we will extend our platform to perform simulations at the global level and answer key questions in TB control.