Fundamentals and applications of continuous-flow microprocessing systems based on supercritical fluids and gas expanded liquids. Microchemical systems have considerable potential in the area of chemical discovery and development. Practical application of these systems requires fundamental understanding and strategies for conversion to appropriate scale. The aim of this project is to overcome such challenges in the development of microstructured continuous-flow technology.
Targeted process development for drug delivery. Matrix assisted ball milling and continuous flow process intensification on rotating surfaces in the form of spinning discs and rotating tubes, and combinations of these, allow the fabrication of nanoparticles for the pharmaceutical industry, with the ability to fine tune the properties of the particles to improve their uptake profiles, while minimising side effects. The research will be conducted through the Centre for Strategic Nano-Fabrication w ....Targeted process development for drug delivery. Matrix assisted ball milling and continuous flow process intensification on rotating surfaces in the form of spinning discs and rotating tubes, and combinations of these, allow the fabrication of nanoparticles for the pharmaceutical industry, with the ability to fine tune the properties of the particles to improve their uptake profiles, while minimising side effects. The research will be conducted through the Centre for Strategic Nano-Fabrication with its science based attention to quality by design for product development at the inception of the science. This, coupled with the involvement of iCeutica which has a strong commercially focused R and D profile, provides a more innovative research culture, and excellent research training. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453963
Funder
Australian Research Council
Funding Amount
$546,352.00
Summary
An integrated nanoscale fabrication, manipulation and characterisation facility. The fabrication of ordered structures at the nanometre scale is essential if the aspirations of nanotechnology are to be achieved. Understanding the fundamental nanoscience controlling the fabrication and operation of such devices is vital. The combination of instruments requested for this project will allow the construction of arrays of nanoparticles, their precise characterisation and the direct measurement of i ....An integrated nanoscale fabrication, manipulation and characterisation facility. The fabrication of ordered structures at the nanometre scale is essential if the aspirations of nanotechnology are to be achieved. Understanding the fundamental nanoscience controlling the fabrication and operation of such devices is vital. The combination of instruments requested for this project will allow the construction of arrays of nanoparticles, their precise characterisation and the direct measurement of interpartice and intermolecular forces at the pN level. Parallel computational chemistry and state of the art experiments will lead to the optimised design of nanostructures that will be applied in diverse areas, including mineral processing, biosensors, photonics, magnetic storage and catalysis.Read moreRead less
Quantum dynamics of solid-state qubits. The primary aim of this project is to carry out a critical assessment of several solid-state qubit systems and quantum logic gate operations through detailed theoretical calculations. This project will address important issues such as precise control of electron flux and spin interactions, optimal operating conditions, errors due to imperfection in the system and possible mechanisms for error elimination, as well as reliable measurements of the output qubi ....Quantum dynamics of solid-state qubits. The primary aim of this project is to carry out a critical assessment of several solid-state qubit systems and quantum logic gate operations through detailed theoretical calculations. This project will address important issues such as precise control of electron flux and spin interactions, optimal operating conditions, errors due to imperfection in the system and possible mechanisms for error elimination, as well as reliable measurements of the output qubit register. In addition, qubit systems have shown themselves to be tiny laboratories in which fundamental concepts in quantum mechanics can be tested and a new regime of physics can be learnt.Read moreRead less
A novel nanoimprinting technology for infrared photovoltaic sensor applications. There is a demonstrated need for state-of-the-art optoelectronic infrared sensors to be available to Australian industry to enable it to be more competitive in national and international marketplaces in strategically important fields such as defence, remote sensing, agriculture, medicine and the environment. The world market for IR optoelectronic sensors is expanding, but at present there is no manufacturer of devic ....A novel nanoimprinting technology for infrared photovoltaic sensor applications. There is a demonstrated need for state-of-the-art optoelectronic infrared sensors to be available to Australian industry to enable it to be more competitive in national and international marketplaces in strategically important fields such as defence, remote sensing, agriculture, medicine and the environment. The world market for IR optoelectronic sensors is expanding, but at present there is no manufacturer of devices in Australia, which puts Australian industry and national security at a disadvantage. This project will go a long way towards providing a national capability by developing a very low cost, simple infrared sensor fabrication process, based on nanoimprint technology. Read moreRead less
Development of the methods to tailor photocatalytic activity of ZnO nanoparticles. This project aims at the development of the methods to tailor the photocatalytic activity of ZnO nanoparticles. Methods to both enhance and reduce the photocatalytic activity for specific applications will be investigated, and the physical and chemical mechanism of photocatalysis-control will be studied. The method developed will be applied for a commercial scale production of ZnO nanoparticles. The effects of ....Development of the methods to tailor photocatalytic activity of ZnO nanoparticles. This project aims at the development of the methods to tailor the photocatalytic activity of ZnO nanoparticles. Methods to both enhance and reduce the photocatalytic activity for specific applications will be investigated, and the physical and chemical mechanism of photocatalysis-control will be studied. The method developed will be applied for a commercial scale production of ZnO nanoparticles. The effects of (a) impurity doping inside of the particles, (b) particle coating, (c) size and morphologies of the particles, and (d) ion-adsorption of the particle surface, to the photocatalytic activity of ZnO nanoparticles will be investigated. The methods developed will be applied for a commercial scale production of ZnO nanoparticles by ANT.Read moreRead less
A nanoengineered solution to drug delivery in bone. This project presents an exciting new approach of applying nanotechnology to bone research. By combining our expertise in nanoengineering of new materials, mathematical modelling and bone biology, this project will result in a well-characterised model for drug delivery into bone and lead to a new therapeutic approach for treating bone diseases.