Place and parametricism: Provocations for the rethinking of design. This project aims to explore whether quantitative methods of digital and parametric design can adequately encompass place. Quantitative digital and parametric approaches increasingly dominate contemporary architecture, but people assume architectural design should be essentially oriented to questions of place. The project will operate through a set of studio provocations based on the fictional places of Mervyn Peake's Gormenghas ....Place and parametricism: Provocations for the rethinking of design. This project aims to explore whether quantitative methods of digital and parametric design can adequately encompass place. Quantitative digital and parametric approaches increasingly dominate contemporary architecture, but people assume architectural design should be essentially oriented to questions of place. The project will operate through a set of studio provocations based on the fictional places of Mervyn Peake's Gormenghast novels. The project is expected to clarify the nature of place and parametricism, and rethink what design itself might be.Read moreRead less
The influence of sway-roll coupling on the dynamics of an inverted sailing yacht in waves. The ability of a sailing yacht to re-right in waves after capsize will influence the safety of those on board in extreme conditions.
The aim of this project is to incorporate the effects of sway-roll coupling into a numerical simulation of the behaviour of an inverted yacht in waves to assess design features which influence re-righting. Experimental work being conducted during 2001 will be extended to ....The influence of sway-roll coupling on the dynamics of an inverted sailing yacht in waves. The ability of a sailing yacht to re-right in waves after capsize will influence the safety of those on board in extreme conditions.
The aim of this project is to incorporate the effects of sway-roll coupling into a numerical simulation of the behaviour of an inverted yacht in waves to assess design features which influence re-righting. Experimental work being conducted during 2001 will be extended to enable the forces on a model of an inverted yacht in a breaking wave to be determined. and incorporated along with theoretical predictions into the simulation.Read moreRead less
Architecture and industry: the migrant contribution to nation-building. This project aims to explore the post-war architectural, rural and industrial landscapes of Australia as shaped by the labour of displaced persons. Migrants after the Second World War were critical to the spatial making of modern Australia. Major federally-funded industries driving post-war nation-building programs depended on the employment of large numbers of war-displaced persons. While the immigrant contribution to natio ....Architecture and industry: the migrant contribution to nation-building. This project aims to explore the post-war architectural, rural and industrial landscapes of Australia as shaped by the labour of displaced persons. Migrants after the Second World War were critical to the spatial making of modern Australia. Major federally-funded industries driving post-war nation-building programs depended on the employment of large numbers of war-displaced persons. While the immigrant contribution to nation-building in cultural terms is well-known, its everyday spatial, architectural and landscape transformations remain unexamined. This project aims to bring to the foreground post-war industry and immigration to comprehensively document a how Australia has uniquely shaped its built environment.Read moreRead less
Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Between the Outback and the Sea: The Place of Cosmopolitanism in Contemporary Australia. 'Place' is an increasingly contested and problematic notion. In contemporary Australia, it arises as a central issue in relations between the indigenous and the 'settled'; between the refugee and the citizen; between the regional and the international. By focusing on the idea of the 'cosmopolitan' as it arises in the Australian context, and particularly with respect to the built environment (often neglected ....Between the Outback and the Sea: The Place of Cosmopolitanism in Contemporary Australia. 'Place' is an increasingly contested and problematic notion. In contemporary Australia, it arises as a central issue in relations between the indigenous and the 'settled'; between the refugee and the citizen; between the regional and the international. By focusing on the idea of the 'cosmopolitan' as it arises in the Australian context, and particularly with respect to the built environment (often neglected in favour of the concepts of 'land' or 'wilderness'), the project will enable a reconfiguration of the significance and meaning of place for ideas of citizenship and identity.
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Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These a ....Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These are significant community issues in both economical and social terms. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest cellular processes associated with aging or disease of the brain, and will provide clues to promoting healthy aging.Read moreRead less
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encodi ....Developing a Unified Theory of Episodic Memory. This project aims to develop a model of episodic memory and to apply the model to both adult and child development data. Unlike current approaches, the model is expected to address multiple memory tasks including item recognition, associative recognition, source recognition and cued recall, and also aims to address reaction time data, allowing different sources of interference causing forgetting in adults to be identified. By addressing both encoding and retrieval processes, the model can assess how changes in different sources of interference modulate performance through the trajectory of early development. Hierarchical Bayesian estimation aims to enable a simultaneous account of multiple tasks and support future deployment in applied contexts.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.