Addressing Evidence Gaps And Developing A Novel Treatment To Reduce The Burden Of Post-traumatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Arthritis caused by knee injury has a devastating personal and economic impact. Research is needed to develop strategies to prevent arthritis and improve outcomes for people living with arthritis. This research will improve treatment of knee injury to reduce arthritis risk, understand why some people are more likely to get knee arthritis, and develop a new treatment to improve outcomes for people living with knee arthritis. A clinical trial will determine if this treatment achieves this aim.
Early Career Industry Fellowships - Grant ID: IE230100468
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Scalable high-performance electrolytic hydrogen generator. The project aims to demonstrate energy-efficient generation of compressed hydrogen by water electrolysis in a high pressure electrolyser test-rig produced by Melbourne company Energys Australia P/L, using high-performance membrane-electrode assemblies. Innovative electrode architectures, membranes, and method for their high through-put lamination will be developed. New knowledge in catalysis, device fabrication and materials science is e ....Scalable high-performance electrolytic hydrogen generator. The project aims to demonstrate energy-efficient generation of compressed hydrogen by water electrolysis in a high pressure electrolyser test-rig produced by Melbourne company Energys Australia P/L, using high-performance membrane-electrode assemblies. Innovative electrode architectures, membranes, and method for their high through-put lamination will be developed. New knowledge in catalysis, device fabrication and materials science is expected to be generated. The major project outcome is sustainable method for generation of compressed hydrogen at significantly reduced cost as compared to the existing technologies. Benefits include industry-ready processes for electrolyser and hydrogen production that support Australian energy industries.Read moreRead less
Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-make ....Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-maker acceptance of the framework. Expected project outcomes include an enhanced capacity to critically analyse existing policies and guide future food and nutrition policy formulation and evaluation. This project would provide significant benefits by helping to promote public health, wellbeing and food system sustainability.Read moreRead less
Integrated Kids Hubs - Ensuring Equity of Access for Children. The Integrated Kids Hubs - Ensuring Equity of Access for Children project aims to determine if integrated Hubs are effective in increasing access to child and family services for disadvantaged urban and regional families with children aged 3 years and under, thus improving early identification of developmental vulnerability, parental wellbeing and capacity, and addressing unmet psychosocial needs. If these issues are not identified a ....Integrated Kids Hubs - Ensuring Equity of Access for Children. The Integrated Kids Hubs - Ensuring Equity of Access for Children project aims to determine if integrated Hubs are effective in increasing access to child and family services for disadvantaged urban and regional families with children aged 3 years and under, thus improving early identification of developmental vulnerability, parental wellbeing and capacity, and addressing unmet psychosocial needs. If these issues are not identified and addressed early, these children will go on to struggle in school and life. We will use a pragmatic trial design (meaning the research is embedded in our usual practice), determine the social return on investment, and establish what is needed to scale up the Hubs across NSW and Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100154
Funder
Australian Research Council
Funding Amount
$399,000.00
Summary
Theory use in social care practice: improving implementation and outcomes . This project aims to harness the power of theorising to advance implementation science. The project expects to generate new knowledge on how frontline workers can use and move beyond their tacit knowledge to strengthen the implementation and effectiveness of programs designed to address pervasive disadvantage and promote positive child and family outcomes. The expected outcome is a tested theoretical model that will inf ....Theory use in social care practice: improving implementation and outcomes . This project aims to harness the power of theorising to advance implementation science. The project expects to generate new knowledge on how frontline workers can use and move beyond their tacit knowledge to strengthen the implementation and effectiveness of programs designed to address pervasive disadvantage and promote positive child and family outcomes. The expected outcome is a tested theoretical model that will inform how frontline workers' critical thinking supports the consolidation of tacit and new knowledge and the use of implementation science. Strengthening understanding of effective program implementation through theory driven inquiry is viable and may generate urgently needed population level change in the social care sector. Read moreRead less
Extracting energy from air: mechanism of a bacterial hydrogenase. The atmosphere has recently been shown to be a key source of energy for diverse soil bacteria. Bacteria use complex enzymes, namely Huc-type hydrogenases, to harvest atmospheric hydrogen directly from air to support growth and survival. However, little is known about how Huc functions within and outside cells. By synergising expertise in microbiology, biochemistry, and chemistry, we will resolve the mechanism, assembly, and integr ....Extracting energy from air: mechanism of a bacterial hydrogenase. The atmosphere has recently been shown to be a key source of energy for diverse soil bacteria. Bacteria use complex enzymes, namely Huc-type hydrogenases, to harvest atmospheric hydrogen directly from air to support growth and survival. However, little is known about how Huc functions within and outside cells. By synergising expertise in microbiology, biochemistry, and chemistry, we will resolve the mechanism, assembly, and integration of Huc, including the basis of its remarkably high affinity and oxygen insensitivity compared to previously studied hydrogenases. This project will enable biotechnological applications, as the first study of an enzyme that extracts energy from air, and has broad ecological and biogeochemical implications.Read moreRead less
Decentralised assets trading, centralised clearing and systemic risk. This project aims to study the effect of regulating over-the-counter (OTC) financial markets on economic performance. The lack of transparency of OTC financial markets may have exacerbated the severity of the 2007-09 financial crisis. In response, regulators around the world decided to mandate centralised clearing of derivatives traded OTC, believing this would reduce system-wide risk. This project will study the regulatory ch ....Decentralised assets trading, centralised clearing and systemic risk. This project aims to study the effect of regulating over-the-counter (OTC) financial markets on economic performance. The lack of transparency of OTC financial markets may have exacerbated the severity of the 2007-09 financial crisis. In response, regulators around the world decided to mandate centralised clearing of derivatives traded OTC, believing this would reduce system-wide risk. This project will study the regulatory change’s effects on market participation, volumes of trade and prices, and the behavioural effect of shifting risk from market participants to clearinghouses. It expects to suggest remedial policies clearinghouses could implement to control market participants’ risk appetite. These can help enhance future productivity and reduce unemployment in Australia.Read moreRead less
Incomplete Information Models for Industrial Organisation. Mergers, acquisitions, and collusive conduct take place in imperfectly competitive environments where firms have incomplete information about others. Despite this, standard workhorse models for analyzing the associated competitive effects assume that firms have complete information and typically only accommodate imperfect competition on one side of the market. This project aims to remedy this deficiency by developing the economic theory ....Incomplete Information Models for Industrial Organisation. Mergers, acquisitions, and collusive conduct take place in imperfectly competitive environments where firms have incomplete information about others. Despite this, standard workhorse models for analyzing the associated competitive effects assume that firms have complete information and typically only accommodate imperfect competition on one side of the market. This project aims to remedy this deficiency by developing the economic theory and associated practical tools for the analysis of competitive effects in settings with incomplete information and market power on both sides. The project work will be presented at seminars and workshops around the globe to both academic audiences and to practitioners at competition authorities. Read moreRead less
The production, use and effect of social work research. This project aims to reform social work research to improve the quality and effectiveness of human services. The human services industry is vital to many people’s quality of life, but lacks innovation and struggles to demonstrate its effectiveness. Crucially for social work, research expands thinking about how to respond to social disadvantage. This project intends to examine the scope and quality of Australian social work research in child ....The production, use and effect of social work research. This project aims to reform social work research to improve the quality and effectiveness of human services. The human services industry is vital to many people’s quality of life, but lacks innovation and struggles to demonstrate its effectiveness. Crucially for social work, research expands thinking about how to respond to social disadvantage. This project intends to examine the scope and quality of Australian social work research in child protection, disability services, and aged care; assess the use of this research to the human services sector and its effect on generating innovation; and develop strategies to advance the production, uptake, and effect of social work research.Read moreRead less
Young people bereaved by domestic homicide. Far-reaching decisions are made about the future of a child bereaved by domestic homicide, including where they should live and whether they should have contact with the perpetrator. Practitioners and policymakers lack empirical and theoretical input to guide these decisions. This fellowship draws upon young people's, caregivers' and professionals' perspectives on children's living arrangements, relationships and identity development post-homicide. It ....Young people bereaved by domestic homicide. Far-reaching decisions are made about the future of a child bereaved by domestic homicide, including where they should live and whether they should have contact with the perpetrator. Practitioners and policymakers lack empirical and theoretical input to guide these decisions. This fellowship draws upon young people's, caregivers' and professionals' perspectives on children's living arrangements, relationships and identity development post-homicide. It expects to generate a theoretical model of children's outcomes as well as actionable advice for policymakers and practitioners. The main benefit will be enhanced capacity to support children, families and professionals in the context of domestic homicide in Australia and abroad. Read moreRead less