HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Improving Global Tuberculosis Control With The AuTuMN Platform
Funder
National Health and Medical Research Council
Funding Amount
$655,059.00
Summary
Tuberculosis (TB) is the world’s leading infectious killer, with the failure of global control responsible for the vast majority of Australia’s cases. Using our robustly developed software platform, we have performed several country-level studies to predict the future burden of disease and compare the impact of alternative responses to controlling the epidemic. In this project, we will extend our platform to perform simulations at the global level and answer key questions in TB control.
Psychosocial and economic impacts of rare diseases on Australian children, families and health professionals. Rare childhood diseases have enormous impacts on children and families; health services, and health professionals. This project will enable Australia to lead the international research effort by using a coordinated approach to study the impacts of rare diseases in order to improve psychosocial, health and economic outcomes for children and families.
Risk Of Hepatitis C Reinfection Among People With Current Injecting Drug Use Following Successful HCV Treatment
Funder
National Health and Medical Research Council
Funding Amount
$2,245,228.00
Summary
In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs ....In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs.Read moreRead less
Determinants of children's physical activity and sedentary behaviour: a follow-up study from early childhood. This project investigates changes in preschool children's physical activity and sedentary behaviour, and influences on these changes, during the important period of transition to school. It will provide important information on how we might assist children to be more active, thereby avoiding the detrimental health and social outcomes of inactivity.
Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring tha ....Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring that the evidence generated has contemporary policy relevance. The project expects to identify clear and actionable policy pathways to reduce child inequities in Australia, which can benefit decision makers by helping them to direct limited public funds towards intervention opportunities that will have the greatest impact.Read moreRead less
Pathways, policies and prevention: better outcomes for western Australian children. This project will provide new knowledge to inform and enable future policy and prevention strategies for improving child health and wellbeing. The collaboration between researchers and policy makers across 11 government departments will deliver a new evidence base for understanding child, family and community level factors that increase or reduce vulnerability to poor outcomes through the utilisation of cross-sec ....Pathways, policies and prevention: better outcomes for western Australian children. This project will provide new knowledge to inform and enable future policy and prevention strategies for improving child health and wellbeing. The collaboration between researchers and policy makers across 11 government departments will deliver a new evidence base for understanding child, family and community level factors that increase or reduce vulnerability to poor outcomes through the utilisation of cross-sectoral population data. This collaboration will inform whole of government intervention and prevention strategies to improve outcomes, as well as evaluate and monitor existing initiatives. This project will provide a model for population-based research and policy development both nationally and internationally.Read moreRead less
Changing children’s chances: Exploring pathways to developmental inequities. This project aims to investigate the causes of health and developmental inequities between Australian children. Inequities are increasingly observed in Australian children’s physical health, social and emotional wellbeing, and academic learning. Such inequities are unjust, unnecessary and potentially preventable. This project aims to understand the pathways leading to these inequities by examining the many contexts in w ....Changing children’s chances: Exploring pathways to developmental inequities. This project aims to investigate the causes of health and developmental inequities between Australian children. Inequities are increasingly observed in Australian children’s physical health, social and emotional wellbeing, and academic learning. Such inequities are unjust, unnecessary and potentially preventable. This project aims to understand the pathways leading to these inequities by examining the many contexts in which children and their families live and grow. Through a series of innovative analyses using existing data, the project aims to identify potentially modifiable factors at the child, family, school, and community level that contribute to developmental inequities. Understanding of the most promising leverage points for interventions to reduce inequities for Australian children could be used to inform policy.Read moreRead less
Impact Of An Ivermectin Mass Drug Administration Program Against Endemic Scabies And Strongyloidiasis
Funder
National Health and Medical Research Council
Funding Amount
$1,289,786.00
Summary
Overseas studies suggest sustainable and long term benefits can be obtained through the use of ivermectin in mass drug administration programs to control parasitic infections. Our study will be a critical first step in establishing if such a program can be successful in a remote Indigenous community setting, where the disease burden from scabies and strongyloidiasis (threadworm infections) is very high.
Families with multiple and complex needs: refocusing on early intervention. Families with multiple and complex needs have been determined to be a priority group in Australia (National Child Protection Framework 2021-31). This study will fill the evidence gap by determining the typologies of families with multiple and complex needs and child protection involvement who face intersecting risk factors (e.g. family violence, mental health, intergenerational trauma, alcohol/drug use, justice involveme ....Families with multiple and complex needs: refocusing on early intervention. Families with multiple and complex needs have been determined to be a priority group in Australia (National Child Protection Framework 2021-31). This study will fill the evidence gap by determining the typologies of families with multiple and complex needs and child protection involvement who face intersecting risk factors (e.g. family violence, mental health, intergenerational trauma, alcohol/drug use, justice involvement, disability, poverty and housing insecurity). Intergenerational (child and parent) linked data in three states will be utilised to investigate these families longitudinal trajectories of system involvement and to identify opportunities for enhanced prevention, points of early intervention and service planning. Read moreRead less