Improving The Evidence Base For Suicide Prevention Initiatives
Funder
National Health and Medical Research Council
Funding Amount
$772,209.00
Summary
The burden of suicide persists partly because we don’t know what works and what doesn’t work in suicide prevention. Relatively little research effort has been invested in studies that can tell us how best to direct resources. The problem is compounded by a disconnect between researchers and decision-makers. Through this Fellowship, Jane Pirkis will develop and implement a model for working with decision-makers to generate the best possible evidence upon which to base suicide prevention policy.
Using Health Literacy (HL) Approaches To Develop And Apply Interventions To Improve Health Services And Generate Equitable Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$697,209.00
Summary
Health literacy is the ability to find, understand and use health information and healthcare services effectively. The Fellowship will advance the understanding of health literacy. It will determine how poor health literacy might cause health inequalities and with this information, develop and test interventions to improve the response of the healthcare system. The research will make it easier for disadvantaged and vulnerable people to get care, be understood and have their needs recognised and ....Health literacy is the ability to find, understand and use health information and healthcare services effectively. The Fellowship will advance the understanding of health literacy. It will determine how poor health literacy might cause health inequalities and with this information, develop and test interventions to improve the response of the healthcare system. The research will make it easier for disadvantaged and vulnerable people to get care, be understood and have their needs recognised and met.Read moreRead less
Understanding And Preventing Adverse Developmental Effects Of Perinatal Infection/inflammation
Funder
National Health and Medical Research Council
Funding Amount
$621,458.00
Summary
Exposure of babies to infection or inflammation within the womb is common and is associated with preterm delivery and illness in newborns. The biggest problem for these babies is lung disease due to inflammation of the lungs before birth and/or in response to lung injury after birth. We are investigating how inflammation alters lung development, and working on developing a novel cell therapy to prevent life-threatening newborn lung disease.
Advancing Aboriginal Australian Oral Health Through Intervention Studies, Longitudinal Studies, Modelling And Surveillance
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Indigenous Australians experience worse oral health than their non-Indigenous counterparts. This Fellowship aims to advance Aboriginal Australian oral health through intervention studies, longitudinal studies, modelling & surveillance. The fellowship will capitalise on past collaborations with local, national and international researchers of repute, and seek to forge new partnerships that will be of benefit to Indigenous oral health at a global level.
We will apply genome-wide approaches to identify the gene networks that regulate the self-renewal and the differentiation of muscle stem cells and their fusion to muscle fibres. These studies will deliver the first characterisation of the molecules and pathways implicated in these processes, which are essential steps of muscle growth.
Disorders of sex development (DSDs) are surprisingly common, and often result in infertility, genital abnormalities, gender mis-assignment and long-term psychological trauma. This research combines expertise in human molecular genetics, mouse developmental biology and protein chemistry to identify genes important for sex determination and development of the gonads, and discover how they contribute to DSD, in order to improve clinical care to patients with DSD.
Developmental Programming: Mechanisms And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$705,501.00
Summary
Disturbances during pregnancy can impact on developmental processes and result in increased risk of disease in later life. This project will examine the impact of perturbations such as maternal stress or alcohol consumption on the development of the placenta and fetal kidney. By gaining an understanding of how these organs are affected by prenatal insults, we are likely to be able to develop more effective intervention strategies to ensure all babies receive a healthy start to life.
I am a developmental biologist studying how transcription factors regulate developmental processes. I have a particular interest in the MYST family of co-activators, their role in regulating self-renewal and lineage determination in stem cells, their role in oncogenesis and targeting these proteins to develop new cancer therapeutics.
Delineating Immune Circuits For Innate And Adaptive Immune Protection
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
The immune system provides the essential frame-work to protect us against infection, disease and to heal tissues after trauma. This is achieved by a complex but elegant network of different types of white blood cells. Understanding the molecular wiring of these cells will provides fundamental insights to how the body fights pathogen infections and cancer and lays the foundation to therapeutic approaches to vaccination and disease treatments.
Disorders Of Gonadal Development: Molecular Approaches To Improved Patient Care
Funder
National Health and Medical Research Council
Funding Amount
$863,413.00
Summary
We will use new genomic technologies to identify the genetic causes of disorders of sex development (DSD), a common and often distressing class of birth defect. Knowing the molecular lesion will take the guesswork out of diagnosis and treatment of DSD children. We will also exploit a new discovery to develop new means of rapid, cost-effective, non-invasive diagnosis and therapy for testicular cancer, the commonest form of cancer in men under 30.