Working With Horses To Promote The Wellbeing Of Aboriginal Youth: An Experiential Learning Approach For The Kimberley
Funder
National Health and Medical Research Council
Funding Amount
$2,516,797.00
Summary
This project aims to implement an Aboriginal-led Equine-Assisted Learning (EAL) program in multiple locations across the Kimberley to enhance the social and emotional wellbeing of Aboriginal youth. EAL is a learning approach where participants learn important life skills by 'doing' activities with horses. These activities enhance problem-solving skills, communication, self‐awareness, and emotional regulation by engaging multiple brain systems, which can help cope with disruptive life stressors.
Staying Connected: Personalising Stroke Recovery And Rehabilitation Through New Technologies For People With Stroke Living At Home.
Funder
National Health and Medical Research Council
Funding Amount
$1,730,999.00
Summary
One in 4 people experience a stroke. On return home the person with stroke is challenged to sense, move, think, and engage in valued activities with an altered brain and body. Yet the current approach to ongoing recovery is limited. We propose to: monitor for markers of recovery using personalised sensors and artificial intelligence; deliver bursts of therapy at point of need, at home; and provide feedback through new technologies and a central hub...to stay connected, and to recover at home.
Yindymarra (to Honour, Respect) Aboriginal Experiences In The Conduct Of Health Research: The Development Of Practical Recommendations To Enhance The Uptake Of Ethical Research Guidelines.
Funder
National Health and Medical Research Council
Funding Amount
$1,015,166.00
Summary
Ethical, high quality research is needed to reduce the health gap between Aboriginal and non-Aboriginal Australians. Currently, there is no critical analysis of the uptake of ethical guidelines. This study will investigate the experiences of Aboriginal communities and Aboriginal health researchers at a national level. Collected data will inform a nationally endorsed set of practical recommendations to guide future Aboriginal health research.
Developing An In Vitro Model Of A Human Blastocyst
Funder
National Health and Medical Research Council
Funding Amount
$890,062.00
Summary
Using novel cellular and molecular technologies we propose to develop an artificial model of an early human blastocyst. This will allow us to study the first initial steps in human development without the use of real embryos. Such a model will not only help us decipher the first steps in human development, but we anticipate it will be essential to study how gene mutations and the environment affect this initial step in human development.
Communication Connect: Improving Long Term Communication And Mental Health Outcomes Following Stroke And Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$1,809,756.00
Summary
The 250,000 Australians living in the community with communication disability caused by stroke and traumatic brain injury experience unacceptably high rates of depression, anxiety, inactivity and social isolation. Their carers experience high levels of burden, and they struggle to access health and community services. We aim to develop and test a program of community and self-managed care, aimed at reversing these negative impacts and reducing reliance on high cost health care services.
Food And Water For Life: Co-creation And Evaluation Of Sustainable Innovations To Strengthen Food And Water Security
Funder
National Health and Medical Research Council
Funding Amount
$1,169,419.00
Summary
Aboriginal and Torres Strait Islander peoples suffer a disproportionate burden of non-communicable diseases. Poor diets, exacerbated by low quality water supplies, are one of the biggest contributors to this. Through our existing long-standing partnership, his project will establish a framework and use regulatory analysis to support the Aboriginal community in Walgett to develop a transformative community-led food and water security action plan to improve the long-term health and well-being.
Vaccine To Prevent Influenza Virus And Bacterial Super-infection.
Funder
National Health and Medical Research Council
Funding Amount
$707,717.00
Summary
Influenza viruses have the ability to pre-dispose infected hosts toward secondary bacterial complications. The mortality of viral infections that are complicated by a concurrent, or subsequent, bacterial infection (known as a super-infection), is often greater than that of either the virus or the bacteria alone. We will develop a novel multi-pathogen vaccine candidate against the major upper respiratory tract pathogens - Influenza A and Streptococcus pyogenes to prevent super-infections.
Growth Factor Directed Developmental And Pathological Lymphangiogenesis
Funder
National Health and Medical Research Council
Funding Amount
$1,048,507.00
Summary
The formation of new lymphatic vessels occurs in normal development and in diseased tissues in cancer and cardiovascular disease. We have developed an understanding of how lymphatics form in development but we understand far less about how they form in disease. This project will apply multidisciplinary approaches, including genetics and computational biology, to compare how lymphatics form in development and disease. We hope to uncover new ways to manipulate this process for therapeutic gain.
Relaxin Receptor Structural Determination To Aid Therapeutic Development
Funder
National Health and Medical Research Council
Funding Amount
$1,249,114.00
Summary
The receptor for the peptide hormone relaxin, RXFP1, is being targeted by numerous drug companies for the treatment of cardiovascular disease. However, the lack of molecular detail of how relaxin binds and activates RXFP1 is hindering new drug development. We will determine the structure of the complex of relaxin bound to RXFP1 and the mechanism by which this activates cells. The knowledge gained will aid in the design of new drugs targeting RXFP1 for the treatment of cardiovascular disease.
Harnessing The Benefits Of Autonomous Vehicles For Health
Funder
National Health and Medical Research Council
Funding Amount
$738,596.00
Summary
The arrival of autonomous vehicles (AVs) will have huge implications for health behaviours, including physical activity and diet. It is critical that appropriate planning processes are undertaken as early as possible to prevent cities of the future being designed around AVs rather than people, thereby losing the potential for this new technology to be harnessed as a means of enhancing health. This project will facilitate the inclusion of health considerations in AV implementation processes.