Optimizing Outpatient Parenteral Antibiotic Therapy To Support Hospital-in-the-home Program Across The Unique Environmental Conditions Of Australia
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
This project aims to solve problems associated with stability and dosing of antibiotic infusions given to patients in their homes, to support decision making by doctors and regulators. Currently, there is a lack of adequate data that complies with contemporary requirements. We will study infusion preparation both in laboratory settings and in ‘real-life’ conditions while being used by patients. We will enhance the stability of antibiotic preparations and optimize doses for effective treatment.
Broadening Choice and Increasing Diversity in Public Schools. Currently, most families are limited to the public school in their catchment area, meaning the area in which they can afford to live. This leads to socio-economically and ethnically homogenous schools and entrenches disadvantage, as well as denying students the crucial life lessons that flow from being part of a diverse student body. This project aims to investigate a model for allocating public school places that integrates catchment ....Broadening Choice and Increasing Diversity in Public Schools. Currently, most families are limited to the public school in their catchment area, meaning the area in which they can afford to live. This leads to socio-economically and ethnically homogenous schools and entrenches disadvantage, as well as denying students the crucial life lessons that flow from being part of a diverse student body. This project aims to investigate a model for allocating public school places that integrates catchment areas. The expected outcome would be a system that gives families a wider choice, enabling them to enrol in out-of-area schools, while ensuring that allocations remain fair, equitable and balanced, and also delivering benefits such as achieving a desired level of diversity in student populations within schoolsRead moreRead less
Testing strategy-proofness in matching markets: an experimental study. This project seeks to test and improve matching algorithms by investigating the effect of advice on strategy-proofness. Matching algorithms are used to solve allocation problems in designed markets (eg school or house allocation problems). Many of the algorithms employed are strategy-proof: participants never gain from strategising, that is, from lying about their preferences. Strategy-proofness had been seemingly validated b ....Testing strategy-proofness in matching markets: an experimental study. This project seeks to test and improve matching algorithms by investigating the effect of advice on strategy-proofness. Matching algorithms are used to solve allocation problems in designed markets (eg school or house allocation problems). Many of the algorithms employed are strategy-proof: participants never gain from strategising, that is, from lying about their preferences. Strategy-proofness had been seemingly validated by experimental research, but new evidence suggests that participants could be prone to follow wrong advice and therefore lie. In order to improve the performance of designed markets, the project proposes to further test strategy-proofness by investigating how advice can affect truth-telling in strategy-proof algorithms and whether learning can counteract or complement the effect of advice.Read moreRead less
Advancing Physiotherapy Management Of Chronic Pain By Improving Implementation Of Evidence-based Practice
Funder
National Health and Medical Research Council
Funding Amount
$115,883.00
Summary
Chronic musculoskeletal pain is major and concerning public health burden and physiotherapists provide a vital and influential role in managing this problem. High level research has demonstrated effective approaches to managing chronic pain yet there appears to be barriers to implementing such strategies clinically. This project aims to explore these barriers with physiotherapists, devise an intervention to overcome them, and test the feasibility and acceptability of the intervention.
Improving Cardiovascular Outcomes Through Better Trials
Funder
National Health and Medical Research Council
Funding Amount
$1,714,215.00
Summary
Randomised trials are the cornerstone of high quality medical practice. There is an urgent need to do more trials but there are major challenges - timely recruitment of participants, inclusion of representative patients and control of costs are issues we face every day. I will commence a series of new trials evaluating interventions for cardiovascular disease. In parallel I will develop and test innovative solutions to the practicalities of doing large-scale studies.
A Phase III Randomised Placebo-controlled Trial Of Mirtazapine As A Pharmacotherapy For Methamphetamine (Ice) Dependence
Funder
National Health and Medical Research Council
Funding Amount
$3,923,009.00
Summary
Crystalline methamphetamine ('ice') is a growing concern in Australia. There are no approved medications that can be used to treat dependence on this drug. This clinical trial will examine whether mirtazapine, a newly identified treatment agent for methamphetamine use, can be used safely and effectively in routine clinical care to manage methamphetamine dependence in Australia.
Overcoming The Barriers To Treatment Of Multi-drug Resistant Gram-negative Bloodstream Infections In Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$447,603.00
Summary
There is a critical need to develop new treatments for children with antibiotic resistant infections. The most important bacteria causing resistant infections are known as Gram-negative bacteria. Doctors treating children with resistant Gram-negative infections are faced with few antibiotic options. This project will discover the most important resistant infections in Australian children, and trial a new antibiotic to help doctors to use it in the right children and at the right dose.
Community Trust In Rural Industries 2022-2025 - Joint RDC Initiative
Funder
Fisheries Research and Development Corporation
Funding Amount
$48,855.43
Summary
A continuation of representative national surveys of the Australian public regarding attitudes towards trust and acceptance of rural industries, trends shifts, and drivers. Objectives: 1. Develop capability across the sector to monitor, anticipate and respond to shifts in the levels oftrust the community has in Australia's rural industries. 2. Build a common language and collective national narrative around the community trust challenge. 3. Identify common best practi ....A continuation of representative national surveys of the Australian public regarding attitudes towards trust and acceptance of rural industries, trends shifts, and drivers. Objectives: 1. Develop capability across the sector to monitor, anticipate and respond to shifts in the levels oftrust the community has in Australia's rural industries. 2. Build a common language and collective national narrative around the community trust challenge. 3. Identify common best practice approaches, strategies and interventions for building, rebuilding andmaintaining community trust. Read moreRead less
Structural safety guidelines for accidental hydrogen explosion hazards . This project aims to develop structural safety guidelines to mitigate hydrogen explosion hazards which can be identified as a major safety concern due to the higher demand worldwide for sustainable energy sources with no carbon emission. The world’s growing demand for hydrogen and Australia’s National Hydrogen Strategy to develop the industry will make Australia a core player in hydrogen production creating a massive econom ....Structural safety guidelines for accidental hydrogen explosion hazards . This project aims to develop structural safety guidelines to mitigate hydrogen explosion hazards which can be identified as a major safety concern due to the higher demand worldwide for sustainable energy sources with no carbon emission. The world’s growing demand for hydrogen and Australia’s National Hydrogen Strategy to develop the industry will make Australia a core player in hydrogen production creating a massive economic opportunity. However, the high flammability and low ignition energy of hydrogen makes it vulnerable to accidental explosions. Hence, this project will address the lack of safety protocols in Australian Standards related to the handling of hydrogen by producing essential design recommendations.Read moreRead less