Probiotic Prawn Oral Immunotherapy (ProPIT) For Treatment Of Prawn Allergy
Funder
National Health and Medical Research Council
Funding Amount
$1,865,369.00
Summary
A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.
The Kids in Communities Study: national investigation of community level effects on children's developmental outcomes. This project (a cross-disciplinary collaboration) will investigate community level factors influencing early childhood developmental outcomes using a mixed methods approach in up to 10 communities across Australia. This will result in a potential set of measures or indicators that reflect communities that are good for children.
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Building connections: schools as community hubs. This project aims to support school systems and planning authorities enhance engagement between schools and local communities. The key objective is to advance the cost-effective development of the infrastructure required to deliver community programs and services from school sites, in addition to education programs for school-aged students. The project expects to generate new knowledge about how best to plan, design, govern and manage facilities a ....Building connections: schools as community hubs. This project aims to support school systems and planning authorities enhance engagement between schools and local communities. The key objective is to advance the cost-effective development of the infrastructure required to deliver community programs and services from school sites, in addition to education programs for school-aged students. The project expects to generate new knowledge about how best to plan, design, govern and manage facilities and infrastructure to enable schools to operate successfully as more than a school, encouraging the development of resilient and connected communities. The outcomes are expected to include a development framework for maximising schools as community hubs.Read moreRead less
Novel Interventions To Address Methamphetamines In Aboriginal Communities, Including A Randomised Trial Of A Web Based Therapeutic Tool Used To Treat Dependence In Clinical Settings.
Funder
National Health and Medical Research Council
Funding Amount
$2,177,908.00
Summary
Methamphetamine use in Aboriginal communities has gained much media attention, despite limited research studies to ascertain the full extent of its use and its impact. We propose a randomised trial of a web based therapeutic tool for use in Aboriginal Medical Services to treat clients using methamphetamines. In addition we will characterise the health and well-being of Aboriginal people who use methamphetamines and trial unique Aboriginal community led interventions to address methamphetamines.
Redesigning Landcare policy to better coordinate across landholders. This project aims to study how landscape-sensitive economic incentives and social norms can be leveraged to enhance the short- and long-term effectiveness of conservation programs. It will yield new knowledge for innovative designs in conservation contracting that is urgently needed to address worsening environmental threats in Australia and worldwide. In collaboration with Nobel laureate Vernon Smith’s team, new methods and pr ....Redesigning Landcare policy to better coordinate across landholders. This project aims to study how landscape-sensitive economic incentives and social norms can be leveraged to enhance the short- and long-term effectiveness of conservation programs. It will yield new knowledge for innovative designs in conservation contracting that is urgently needed to address worsening environmental threats in Australia and worldwide. In collaboration with Nobel laureate Vernon Smith’s team, new methods and protocols will improve our ability to generate better data and better understand how social and incentive mechanisms can constructively interact to facilitate collaborative environmental action. Results will help make the achievement of environmental targets and the use of public funds more cost-effective. Read moreRead less
Interventions To Improve Outcomes For Young Aboriginal And Torres Strait Islander People In Sexually Transmissible Infections Blood Borne Viruses And For People Using Methamphetamines
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
This ECF will enable research to be carried out in the domains of sexually transmissible infections (STI) and blood borne viruses (BBV) and specifically methamphetamine (MA) use in Aboriginal communities nationally. Specific research outcomes will be the establishment of an Aboriginal primary health care and behavioural surveillance network for STIs/BBVs in nationally dispersed clinical hubs (CRE), and an improved understanding of interventions to address MA in Aboriginal communities.
Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women ....Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women. The project uses a novel approach that gives young women a voice in how five Anglicare end-users (the research partners) and other end-users can enhance their service provision in the welfare and justice sectors and become models of best practice.Read moreRead less
Identifying and resolving challenges to the effectiveness of collective apologies. It is increasingly common for nations and organisations to apologise for current or past wrongdoing. This research investigates the unique psychological reasons for why collective apologies (as opposed to interpersonal ones) might struggle to win acceptance for victim groups; with an eye to identifying conditions that facilitate intergroup forgiveness.
The psychology of gridlock: Compromise, coalitions, and radicalisation. This project aims to test an innovative psychological model of collective gridlock. Using interviews, surveys, experiments, small group research, and analysis of social media data, the project aims to examine critical pathways in gridlock psychology, where opponents are locked into mutually suboptimal outcomes, unable to move forward. These pathways include the exit or self-censorship of moderates; normative pressure towards ....The psychology of gridlock: Compromise, coalitions, and radicalisation. This project aims to test an innovative psychological model of collective gridlock. Using interviews, surveys, experiments, small group research, and analysis of social media data, the project aims to examine critical pathways in gridlock psychology, where opponents are locked into mutually suboptimal outcomes, unable to move forward. These pathways include the exit or self-censorship of moderates; normative pressure towards purity and refusal to compromise; tactical choices to avoid coalitions; and radicalisation. The research aims to develop novel interventions to reduce polarisation and radicalisation, and to promote compromises, which together will help society respond more nimbly and effectively to social and environmental challenges.Read moreRead less