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Repulsive van der Waals forces and Brownian ratchet motors: manipulating thermal and quantum Fluctuations. A fundamental problem with miniaturizing machines and mechanical devices below the micron scale is the issue of friction and lubrication. One way to completely circumvent the need for lubrication is to use a little-studied phenomenon known as 'repulsive van der Waals forces', to create materials that fundamentally repel each other in certain fluid environments. This effect is very large at ....Repulsive van der Waals forces and Brownian ratchet motors: manipulating thermal and quantum Fluctuations. A fundamental problem with miniaturizing machines and mechanical devices below the micron scale is the issue of friction and lubrication. One way to completely circumvent the need for lubrication is to use a little-studied phenomenon known as 'repulsive van der Waals forces', to create materials that fundamentally repel each other in certain fluid environments. This effect is very large at the nanoscale and this proposal examines how such forces can be used to make 'lubricant free' motors and nanomachines. This will open up the possibility of building small and portable sensors, actuators, microfluidic devices and eventually active drug delivery systems for health applications.Read moreRead less
Nanocrystal Electronics: A Sol-Gel Approach. Australia is building capability in printable electronics, which will supersede traditional semiconductor fabrication methods. The main goals are to mass produce key electronic structures such as display devices, solar cells and sensors using cheaper, non-clean room based technologies via ink-jet printing and other high throughput methods. The integration of sol-gel based materials into roll-to-roll manufacturing will advance Australian manufacturing ....Nanocrystal Electronics: A Sol-Gel Approach. Australia is building capability in printable electronics, which will supersede traditional semiconductor fabrication methods. The main goals are to mass produce key electronic structures such as display devices, solar cells and sensors using cheaper, non-clean room based technologies via ink-jet printing and other high throughput methods. The integration of sol-gel based materials into roll-to-roll manufacturing will advance Australian manufacturing capabilities and generate new jobs in the rapidly growing printable electronics field.Read moreRead less
Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design ....Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design of systems that function much more closely to human milk will enable the development of new products with flow on benefits in human nutrition and increased utilisation of products from our dairy industry.Read moreRead less
Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide f ....Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide further employment for Australians, building on Universal Biosensor’s proven record of commercialization in Australia. The project will lead to training of Australian researchers in nanotechnology and in utilization of key Australian science infrastructure including the Australian Synchrotron and the Melbourne Centre for Nanofabrication.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101504
Funder
Australian Research Council
Funding Amount
$438,026.00
Summary
Crossing restrictive biobarriers with self-assembled lipid nanocarriers. This project aims to determine how nanoscale objects which mimic the surface of cells behave in biologically relevant environments. This project expects to generate new knowledge in physical chemistry by complementing innovative surface chemistry design and characterisation with data science approaches. The expected outcome of this project is identification of the mode of interaction of these biomimetic objects with cells, ....Crossing restrictive biobarriers with self-assembled lipid nanocarriers. This project aims to determine how nanoscale objects which mimic the surface of cells behave in biologically relevant environments. This project expects to generate new knowledge in physical chemistry by complementing innovative surface chemistry design and characterisation with data science approaches. The expected outcome of this project is identification of the mode of interaction of these biomimetic objects with cells, which may then reveal a new pathway for the delivery of pharmaceuticals. This could provide significant future benefits in the treatment of neurological diseases and bacterial infections, by overcoming the barrier that the cell surface presents to the uptake of many medicinal drugs.Read moreRead less
Engineered materials for future energy technologies. The development of new technologies to be applied in fuel generation, energy conversion and environmental remediation will have wide national and international impact. The cross-disciplinary and cross-institution research program proposed will draw on expertise within Australia and in Europe for the fabrication of materials for next generation energy devices. In the future, there is the potential that these materials could be fabricated within ....Engineered materials for future energy technologies. The development of new technologies to be applied in fuel generation, energy conversion and environmental remediation will have wide national and international impact. The cross-disciplinary and cross-institution research program proposed will draw on expertise within Australia and in Europe for the fabrication of materials for next generation energy devices. In the future, there is the potential that these materials could be fabricated within Australia and therefore lead to employment nationally, and income generated through the export of advanced catalysts, solar cells and sequestration materials.Read moreRead less
Electrochemistry of redox-active non-metal compounds. Unsaturated compounds of heavier non-metal elements can exist in multiple stable redox states. The interconversion is best assessed by electrochemical techniques, which can measure the energetics and the mechanism of the redox processes involved in both solution and solid state phases. Compounds to be studied will be prepared in the Canadian laboratories of the partner investigator. The electrochemical and spectroelectrochemical properties ....Electrochemistry of redox-active non-metal compounds. Unsaturated compounds of heavier non-metal elements can exist in multiple stable redox states. The interconversion is best assessed by electrochemical techniques, which can measure the energetics and the mechanism of the redox processes involved in both solution and solid state phases. Compounds to be studied will be prepared in the Canadian laboratories of the partner investigator. The electrochemical and spectroelectrochemical properties will initially be investigated in Australia during the visit of the partner investigator to Monash University with follow up studies in both countries. The mutual skills of synthesis and electrochemistry in the Canadian-Australian laboratories are essential to the project.Read moreRead less
Controlling Anisotropic Growth of Metal Oxide Crystals in Aqueous Solution by Selective Adsorption of Small Molecules. The proposed research will enhance our ability to make both light emitting diodes (LEDs) and piezoelectric actuators from ZnO. LEDs are a high efficiency light source that save energy compared to conventional illumination sources and can be fabricated in thin films. The proposal is to also bring the technology for device fabrication to Australia where it can ultimately be used ....Controlling Anisotropic Growth of Metal Oxide Crystals in Aqueous Solution by Selective Adsorption of Small Molecules. The proposed research will enhance our ability to make both light emitting diodes (LEDs) and piezoelectric actuators from ZnO. LEDs are a high efficiency light source that save energy compared to conventional illumination sources and can be fabricated in thin films. The proposal is to also bring the technology for device fabrication to Australia where it can ultimately be used to broaden the economic base of the country. The knowledge of crystal growth rate and crystal morphology control can be applied to improvements in the efficiency of alumina production which is already an important contributor to Australian exports.Read moreRead less
Spectroscopy of Single Quantum Dots. Colloidal semiconductor quantum dots are materials with promising applications in flat panel displays, biosensors, quantum dot lasers, and optical communication elements. Many of the applications are novel and require firm understanding of the physical and chemical properties of quantum dots to optimise reliability and performance. To fulfil the technological promise of fluorescent quantum dots, problems relating to quantum yield and photostability urgently n ....Spectroscopy of Single Quantum Dots. Colloidal semiconductor quantum dots are materials with promising applications in flat panel displays, biosensors, quantum dot lasers, and optical communication elements. Many of the applications are novel and require firm understanding of the physical and chemical properties of quantum dots to optimise reliability and performance. To fulfil the technological promise of fluorescent quantum dots, problems relating to quantum yield and photostability urgently need to be resolved. These issues will be addressed through spectroscopic studies of single quantum dots both in vacuum and in condensed phases. Ultimately, the findings will guide rational design of nanoscale devices based on quantum dot luminescence.Read moreRead less
Causes of and Cures for Microbiological Foams in Activated Sludge Wastewater Treatment Plants. Little is known of the true diversity of the bacteria causing foaming in activated sludge systems, or why and how they cause these foams. This application seeks funds for an interdisciplinary approach to address these issues, involving input from microbiologists and surface chemists and physicists. Molecular techniques will be used to determine precisely the foaming bacterial communities and their phys ....Causes of and Cures for Microbiological Foams in Activated Sludge Wastewater Treatment Plants. Little is known of the true diversity of the bacteria causing foaming in activated sludge systems, or why and how they cause these foams. This application seeks funds for an interdisciplinary approach to address these issues, involving input from microbiologists and surface chemists and physicists. Molecular techniques will be used to determine precisely the foaming bacterial communities and their physiology, while their surface chemistry and organisation will be studied to understand the mechanisms involved in foaming with the intention of developing control strategies for this global problem suitable for large scale application.Read moreRead less