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The cognitive and motivational consequences of affect in interpersonal behavior. Affect plays a major role in health and social adjustment and has a marked influence on many everyday behaviours, yet the mechanisms linking affect to thinking and behaviour remain poorly understood. These studies will produce a national and community benefit by contributing to our understanding of how affect influences thinking and behaviour. The project will develop a new, comprehensive theory of affective influen ....The cognitive and motivational consequences of affect in interpersonal behavior. Affect plays a major role in health and social adjustment and has a marked influence on many everyday behaviours, yet the mechanisms linking affect to thinking and behaviour remain poorly understood. These studies will produce a national and community benefit by contributing to our understanding of how affect influences thinking and behaviour. The project will develop a new, comprehensive theory of affective influences and the real-life consequences of affect in relationships, health, organisational, educational, marketing and clinical settings will also be explored. The project will contribute to Australia's research capability by training doctoral and postdoctoral students, and fostering international research collaboration.
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Investigating the social brain: The neural basis of the link between depressed mood and social cognition. Mood and social relationships are amongst the most important determinants of well being, life functioning, and both mental and physical health. To understand how mood and social behaviour interact, this project will examine the brain mechanisms that are responsible for the impact of mood states on processing social threat stimuli (e.g., stimuli suggesting humiliation, rejection or defeat). T ....Investigating the social brain: The neural basis of the link between depressed mood and social cognition. Mood and social relationships are amongst the most important determinants of well being, life functioning, and both mental and physical health. To understand how mood and social behaviour interact, this project will examine the brain mechanisms that are responsible for the impact of mood states on processing social threat stimuli (e.g., stimuli suggesting humiliation, rejection or defeat). This work will have important implications for understanding vulnerability to recurrent depression, where these processes have been implicated in previous research. The high prevalence of these disorders, and the high cost that they represent to society, makes basic research of this type vital at this time.Read moreRead less
Selective information processing and anxiety problems. Anxiety problems cost Australia over $1 billion per annum, and affect up to 16% of some Australian populations. Previous research by the applicants, and others, recently has established that certain patterns of selective information processing causally underpin elevated vulnerability to anxiety. The present program will serve to distinguish the functional contributions made by two specific classes of processing selectivity to two key dimensi ....Selective information processing and anxiety problems. Anxiety problems cost Australia over $1 billion per annum, and affect up to 16% of some Australian populations. Previous research by the applicants, and others, recently has established that certain patterns of selective information processing causally underpin elevated vulnerability to anxiety. The present program will serve to distinguish the functional contributions made by two specific classes of processing selectivity to two key dimensions of anxiety vulnerability. It is designed to produce novel cognitive technologies capable not only of predicting, but also of attenuating, both the tendency to experience anxiety reactions to stress, and the subsequent persistent of anxiety over time.Read moreRead less
How biased engagement with, and biased disengagement from, emotional information contribute to alternative dimensions of anxiety vulnerability. Anxiety problems cost Australia over $1 billion per annum, and affect up to 16% of some Australian populations. Previous research by the applicants, and others, recently has established that certain patterns of selective information processing causally underpin elevated vulnerability to anxiety. The present program will serve to distinguish the functiona ....How biased engagement with, and biased disengagement from, emotional information contribute to alternative dimensions of anxiety vulnerability. Anxiety problems cost Australia over $1 billion per annum, and affect up to 16% of some Australian populations. Previous research by the applicants, and others, recently has established that certain patterns of selective information processing causally underpin elevated vulnerability to anxiety. The present program will serve to distinguish the functional contributions made by two specific classes of processing selectivity to two key dimensions of anxiety vulnerability. It is designed to produce novel cognitive technologies capable not only of predicting, but also of attenuating, both the tendency to experience anxiety reactions to stress, and the subsequent persistence of anxiety over time.Read moreRead less
Epigenetic mechanisms regulating sex differences in fear-related learning and memory. Anxiety disorders represent an enormous burden on society and are associated with premature aging and infertility in men and women. Evidence also indicates that parental anxiety affects child development. Given that fear-related learning has an important influence on emotional health which, in turn, affects lifestyle and the aging process, an understanding of the neural mechanisms mediating sex differences in ....Epigenetic mechanisms regulating sex differences in fear-related learning and memory. Anxiety disorders represent an enormous burden on society and are associated with premature aging and infertility in men and women. Evidence also indicates that parental anxiety affects child development. Given that fear-related learning has an important influence on emotional health which, in turn, affects lifestyle and the aging process, an understanding of the neural mechanisms mediating sex differences in fear learning will enhance our ability to develop better therapeutic approaches for treating anxiety and preventing relapse, potentially through a gender-specific approach. The studies outlined in this proposal will have implications for promoting and maintaining good health.Read moreRead less
Body image instability, disordered eating and muscle dysmorphia. Body image is a serious public health issue. Dissatisfaction with body shape promotes disordered eating in females who fast and purge to lose weight, and muscle dysmorphia in males who over-exercise and use steroids to gain muscle. We will test the idea that these psychological disorders stem from an unstable body image. Our research will reveal the fundamental risk factors associated with disordered eating and muscle dysmorphia an ....Body image instability, disordered eating and muscle dysmorphia. Body image is a serious public health issue. Dissatisfaction with body shape promotes disordered eating in females who fast and purge to lose weight, and muscle dysmorphia in males who over-exercise and use steroids to gain muscle. We will test the idea that these psychological disorders stem from an unstable body image. Our research will reveal the fundamental risk factors associated with disordered eating and muscle dysmorphia and allow us to identify at-risk individuals on the basis of their body image instability. It will also predict patients' amenability to treatments that target body image, thereby improving outcomes for these individuals.Read moreRead less
Electrophysiological correlates of verbal and visuospatial working memory. Successful interaction with the world is dependent on "working memory". This memory system holds things in mind, while relating them to the past and planning for the future. A carefully controlled task, presented on a computer screen, systematically increases the number of items to be kept in mind. Accuracy and speed of matching the items are measured. The results will contribute to a theory of what processes are used ....Electrophysiological correlates of verbal and visuospatial working memory. Successful interaction with the world is dependent on "working memory". This memory system holds things in mind, while relating them to the past and planning for the future. A carefully controlled task, presented on a computer screen, systematically increases the number of items to be kept in mind. Accuracy and speed of matching the items are measured. The results will contribute to a theory of what processes are used in working memory and how the human brain manages these processes.Read moreRead less
Regulating anger: Cognitive reappraisal, emotional suppression, and post-event rumination. Australians bear the substantial psychological, social, and economic costs associated with unrestrained anger. Anger problems are associated with school and work difficulties, poor social relationship quality, alcohol and drug use, financial and legal difficulties, premature cardiovascular mortality, and clinically significant mental health problems. Anger and aggression also cause much harm to society th ....Regulating anger: Cognitive reappraisal, emotional suppression, and post-event rumination. Australians bear the substantial psychological, social, and economic costs associated with unrestrained anger. Anger problems are associated with school and work difficulties, poor social relationship quality, alcohol and drug use, financial and legal difficulties, premature cardiovascular mortality, and clinically significant mental health problems. Anger and aggression also cause much harm to society through crime, domestic abuse, and workplace violence among others. The Australian Institute of Criminology estimates the cost of assault, sexual assault, and homicide in Australia at over $2.5 billion per year. The insights gained from this research may help ameliorate these negative consequences of anger.Read moreRead less
Identifying risk markers for depression: A cognitive neuroscience approach. This project will establish objective markers for detecting early signs of depression. These markers are crucial in enabling early intervention to limit the course of depression. They will also benefit the development of prevention strategies, since they provide a means to identify high risk individuals. Currently there exists no simple and objective test or set of markers that can detect the early signs of depression. T ....Identifying risk markers for depression: A cognitive neuroscience approach. This project will establish objective markers for detecting early signs of depression. These markers are crucial in enabling early intervention to limit the course of depression. They will also benefit the development of prevention strategies, since they provide a means to identify high risk individuals. Currently there exists no simple and objective test or set of markers that can detect the early signs of depression. The available tests provide information relevant to the later-stage of clinical depression only. In this regard, non-invasive and objective markers are urgently required to limit the burden of depression. In Australia, $3.3 billion in productivity and 12 million working days are lost each year as a result of depression.Read moreRead less
Gene-brain pathways in emotional brain stability and instability. Emotional instability is a defining trait of major mental illnesses. The ability to identify individuals susceptible to emotional instability will be important in limiting the burden of disease from these illnesses. Mental conditions cost the Australian economy approximately $14.9 bill p/a, and depression will be the second leading contributor to burden of disease by 2020. The project will provide the first evidence for the combin ....Gene-brain pathways in emotional brain stability and instability. Emotional instability is a defining trait of major mental illnesses. The ability to identify individuals susceptible to emotional instability will be important in limiting the burden of disease from these illnesses. Mental conditions cost the Australian economy approximately $14.9 bill p/a, and depression will be the second leading contributor to burden of disease by 2020. The project will provide the first evidence for the combination of gene-brain-behaviour markers which best capture emotional instability versus resilience. This evidence base will be crucial to developing new tools and strategies for early intervention, and ultimately prevention, for these conditions of mental health.Read moreRead less