The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced gen ....The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced genetic engineering, the development of new principles and systems for information storage and transmission, and the design of artificial systems capable of self-referential assembly in other environments.Read moreRead less
Principles of Quantum Information Science. The use of quantum mechanical systems to carry and process information is enabling a revolution in information technology through innovations such as quantum computation and quantum teleportation. This project investigates the fundamental theory of quantum information science. The project aims to formulate general principles governing the power and behaviour of quantum information. These principles will, in turn, enable the development of powerful new ....Principles of Quantum Information Science. The use of quantum mechanical systems to carry and process information is enabling a revolution in information technology through innovations such as quantum computation and quantum teleportation. This project investigates the fundamental theory of quantum information science. The project aims to formulate general principles governing the power and behaviour of quantum information. These principles will, in turn, enable the development of powerful new applications of quantum information. Principal areas to be addressed include: general conditions for a physical system to be usable for quantum computation, the development of new algorithms for quantum computers, the development of new quantum communication protocols, and the theory of quantum entanglement.Read moreRead less
Climate change: adaptation and resilience in the face of uncertainty. Climate change poses a wide range of challenges to Australia's agricultural sector and for the management of natural ecosystems. These challenges are recognised in the National Research Priorities 1, An Environmentally Sustainable Australia, and 4, Safeguarding Australia. The potential economic costs of climate change to vital national assets such as the Murray-Darling Basin and the Great Barrier Reef, amount to billions of do ....Climate change: adaptation and resilience in the face of uncertainty. Climate change poses a wide range of challenges to Australia's agricultural sector and for the management of natural ecosystems. These challenges are recognised in the National Research Priorities 1, An Environmentally Sustainable Australia, and 4, Safeguarding Australia. The potential economic costs of climate change to vital national assets such as the Murray-Darling Basin and the Great Barrier Reef, amount to billions of dollars per year, and ecological costs are even more significant. Uncertainty about the rate at which climate change will take place and about effects in different regions is central to the problem. This project will explore adaptive management strategies that promote resilience in the face of uncertainty.
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Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised impor ....Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised importance, this program will have direct implications in areas of condensed matter physics, quantum statistical mechanics, particle physics, complex systems, quantum information science and technology, quantum computation, engineered quantum systems and nanotechnology. Read moreRead less
New approaches to functional and structural genomics. Genome sequencing has revealed complete sets of macromolecules that make up our cells. We now need to learn how these macromolecules work together in a coordinated fashion. The proposed research will lead to the discovery of new biological molecules, interactions and processes essential for the function of cells, identify new therapeutic targets and strategies to combat disease, identify new concepts in bio- and nanotechnology, and train new ....New approaches to functional and structural genomics. Genome sequencing has revealed complete sets of macromolecules that make up our cells. We now need to learn how these macromolecules work together in a coordinated fashion. The proposed research will lead to the discovery of new biological molecules, interactions and processes essential for the function of cells, identify new therapeutic targets and strategies to combat disease, identify new concepts in bio- and nanotechnology, and train new interdisciplinary researchers. It will underpin the National Research Priorities (Frontier Technologies for Building and Transforming Australian Industries, and Promoting and Maintaining Good Health) and help Australia capitalise on a plethora of opportunities for future economic and health benefits.Read moreRead less
Television in the post-broadcast era: the role of old and new media in the formation of national communities. This Federation Fellowship program will examine the place of television in a range of national locations during the post-broadcast era, addressing its socio-cultural function for the citizen as well as considering the competing or complementary roles played by new forms of online journalism. The program will provide a unique international comparative overview of contemporary media system ....Television in the post-broadcast era: the role of old and new media in the formation of national communities. This Federation Fellowship program will examine the place of television in a range of national locations during the post-broadcast era, addressing its socio-cultural function for the citizen as well as considering the competing or complementary roles played by new forms of online journalism. The program will provide a unique international comparative overview of contemporary media systems in the midst of dramatic change. The expertise, critical mass and findings developed within the program will equip Australia to better understand and manage the complex role the media plays in socio-cultural change, while providing cutting edge policy advice to government and industry.Read moreRead less
Science for resilience of coral reef systems. Hughes's Fellowship has enormous capacity to provide economic, cultural, environmental and social benefits for Australia. The coral reefs of Australia, particularly the Great Barrier Reef, Ningaloo Reef, and Lord Howe Island World Heritage Area are Australian national icons, of great economic, social, and aesthetic value to this country. Hughes and his collaborators in a newly-created ARC Centre of Excellence will be the premier providers of the scie ....Science for resilience of coral reef systems. Hughes's Fellowship has enormous capacity to provide economic, cultural, environmental and social benefits for Australia. The coral reefs of Australia, particularly the Great Barrier Reef, Ningaloo Reef, and Lord Howe Island World Heritage Area are Australian national icons, of great economic, social, and aesthetic value to this country. Hughes and his collaborators in a newly-created ARC Centre of Excellence will be the premier providers of the scientific expertise that underpins the management of Australian reefs, which is vital for the sustainable use of biodiversity goods and services (e.g. by the tourist industry, fisheries, and recreational users).Read moreRead less
Biohumanities: Philosophical, Historical, and Socio-Cultural Studies of Contemporary Bioscience. Improving understanding of the meaning and implications of contemporary bioscience, especially genetics and molecular biology, through bioliterate research in the humanities and social sciences, and conversely through better assimilation of bioscience and its significance by the humanities and social sciences. The research will be conducted in close collaboration with the Australian scientific commun ....Biohumanities: Philosophical, Historical, and Socio-Cultural Studies of Contemporary Bioscience. Improving understanding of the meaning and implications of contemporary bioscience, especially genetics and molecular biology, through bioliterate research in the humanities and social sciences, and conversely through better assimilation of bioscience and its significance by the humanities and social sciences. The research will be conducted in close collaboration with the Australian scientific community and will be disseminated back to the scientific community, to the humanities and to the Australian public. The project will bring to Australia the strengths of the applicant's existing collaborations with leading research centres in this field in the USA, UK and Canada.Read moreRead less
Sustainable reform of the Murray-Darling system: Property rights, uncertainty and institutions. The project will develop tools for the modelling of uncertainty in the absence of probabilities and with imperfect knowledge about possible events. It will also formalise and assess the precautionary principle for the sustainable management of complex systems. Finally, the project will apply these tools to analyse and improve policies for the reform of property rights, institutions and land and water ....Sustainable reform of the Murray-Darling system: Property rights, uncertainty and institutions. The project will develop tools for the modelling of uncertainty in the absence of probabilities and with imperfect knowledge about possible events. It will also formalise and assess the precautionary principle for the sustainable management of complex systems. Finally, the project will apply these tools to analyse and improve policies for the reform of property rights, institutions and land and water management in the Murray?Darling system. The project will assist in the formulation of sustainable responses to problems of drought and irrigation related salinity in the Murray?Darling system.Read moreRead less
Stochastic Modelling of Genetic Regulatory Networks: Subtitle - Genetic Regulation is a Noisy Business. The completion of the human genome marked the culmination of one hundred years of reductionist science in cell biology. Although further bioinformatics analysis will continue, the focus is shifting towards synthesis and understanding how the regulatory genetic components dynamically interact to form functional phenotypes. The key to this is the understanding of the roles of stochasticity in ....Stochastic Modelling of Genetic Regulatory Networks: Subtitle - Genetic Regulation is a Noisy Business. The completion of the human genome marked the culmination of one hundred years of reductionist science in cell biology. Although further bioinformatics analysis will continue, the focus is shifting towards synthesis and understanding how the regulatory genetic components dynamically interact to form functional phenotypes. The key to this is the understanding of the roles of stochasticity in cellular processes. This project will explore these roles and will develop an integrated complex systems modelling, simulation and visualisation framework. This will be used on an exemplar application for lineage commitment in haematopoiesis and for exploring and validating genetic regulatory models in general.Read moreRead less