Post Synaptic Density Scaffold Proteins In The Growth Cone: Homer And Shank, Crucial For Calcium Signaling.
Funder
National Health and Medical Research Council
Funding Amount
$237,909.00
Summary
Our brain is a complex, yet precise electrical circuit. Understanding how the embryonic brain is wired has direct implications for all aspects of life, from the growing foetus in mother's womb, to learning algebra and for maintaining the active memories of our ageing population. This project aims to provide new insight into understanding how the embryonic brain is wired, crucial information for future pharmacological or gene therapy approaches to mental illness, ageing, and neuronal injury.
Modulation Of Calcium Signalling By Acetylcholine In The Basolateral Amygdala
Funder
National Health and Medical Research Council
Funding Amount
$266,748.00
Summary
The amygdala is an area of the brain involved in assigning emotional significance to sensory stimuli. This grant examines the cellular processes involved in making these associations. Specifically, it studies the relationship between two signalling molecules implicated in association learning, acetylcholine and calcium. This research will test hypotheses of memory formation and provide insight into disorders linked to detrimental emotional associations, such as anxiety and addiction.