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Disgust as a psychosocial defence against infectious disease. Globally, around 1 in 4 deaths result from infectious disease. Humans have evolved two basic means to combat this - an immune system and behaviours to avoid getting sick. This project examines one such behaviour, disgust, and aims to determine its role in disease avoidance. Studying disgust can lead to novel insights into behaviours as diverse as risky sexual decision-making and illness-related stigmatisation (e.g. of people with AID ....Disgust as a psychosocial defence against infectious disease. Globally, around 1 in 4 deaths result from infectious disease. Humans have evolved two basic means to combat this - an immune system and behaviours to avoid getting sick. This project examines one such behaviour, disgust, and aims to determine its role in disease avoidance. Studying disgust can lead to novel insights into behaviours as diverse as risky sexual decision-making and illness-related stigmatisation (e.g. of people with AIDS or cancer). Disgust can also be used to directly improve human health. For example, it can be exploited to boost hand hygiene. If widely applied, this simple measure could annually save an estimated 1.5 million children's lives, reduce rates of flu, colds, food poisoning and hospital acquired infections.Read moreRead less
Special Research Initiatives - Grant ID: SR0354797
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance co ....The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance communication, bring together innovative skill sets, create linkages, generate focussed research programs and foster novel commercial opportunities. Ultimately the Initiative and Network will deliver an improved quality of life, reduced healthcare costs, and increased productivity to Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989541
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will c ....High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will contribute to the priority area 'Promoting and Maintaining Good Health'. In addition, the new equipment will extend capabilities and postgraduate training in chemistry, nanotechnology, and biomedicine (the priority area of 'Frontier Technologies for Building and Transforming Australian Industries').Read moreRead less
Modelling applications of nanomaterials in biology and medicine. This proposal will address fundamental issues related to nanomaterials and their applications in biology and medicine. Accurate mathematical models will be formulated, leading to new practical techniques in nanobiotechnology, safe and effective methods to diagnose and cure diseases including cancer via targeted drug and gene delivery, and detection methods for biological hazards, such as those arising from biological terrorism. The ....Modelling applications of nanomaterials in biology and medicine. This proposal will address fundamental issues related to nanomaterials and their applications in biology and medicine. Accurate mathematical models will be formulated, leading to new practical techniques in nanobiotechnology, safe and effective methods to diagnose and cure diseases including cancer via targeted drug and gene delivery, and detection methods for biological hazards, such as those arising from biological terrorism. The research facility proposed involves significant training of applied mathematicians at honours, PhD and postdoctoral levels and multidisciplinary collaboration, ensuring that Australia maintains and develops an expertise in nanobiotechnology well into the future.Read moreRead less
Checking the validity of photographic identification documents: Enhancing the performance of security personnel through increased understanding of unfamiliar face processing. The ability to accurately establish the identity of an individual is central to the national security of Australia. Identity checking often relies on facial photographs contained on passports and other documents. Despite the introduction of automated systems, the decision whether a photograph is of a person rests with human ....Checking the validity of photographic identification documents: Enhancing the performance of security personnel through increased understanding of unfamiliar face processing. The ability to accurately establish the identity of an individual is central to the national security of Australia. Identity checking often relies on facial photographs contained on passports and other documents. Despite the introduction of automated systems, the decision whether a photograph is of a person rests with human operators. Research by CI has demonstrated that this task is difficult and error prone. The proposed research seeks to improve performance by developing a fuller understanding of the nature of the task and the limits of the operators' abilities and by testing possible training and selection procedures.Read moreRead less
Modelling disease evolution and emergence. Approximately 75% of all emergent diseases have established in humans having switched from other species: Human Immunodeficiency Virus (HIV), Malaria, SARS (Severe Acute Respiratory Syndrome), Ebola, West Nile Virus and many more. Further, cross species infections put our biodiversity and economy at risk: plant and animal diseases entering Australia can destroy crops and at-risk native species. This project will provide for the first time the statistica ....Modelling disease evolution and emergence. Approximately 75% of all emergent diseases have established in humans having switched from other species: Human Immunodeficiency Virus (HIV), Malaria, SARS (Severe Acute Respiratory Syndrome), Ebola, West Nile Virus and many more. Further, cross species infections put our biodiversity and economy at risk: plant and animal diseases entering Australia can destroy crops and at-risk native species. This project will provide for the first time the statistical framework for scientists to assess risk of such diseases entering Australia as a key to combating them.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989920
Funder
Australian Research Council
Funding Amount
$750,000.00
Summary
Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a c ....Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a current unmet need for scientists in this country and will provide cutting-edge technologies to Australian researchers so they can better detect, understand, and treat human, animal and plant diseases and the environmental impact of climate change.Read moreRead less
Prediction and optimisation of the acoustic performance of mufflers for sleep apnea devices. ResMed is a world leader in the technology of developing products for treating obstructive sleep apnea (OSA). ResMed provided the first successful non-invasive treatment of OSA with their sleep apnea device. Noise reduction is an important issue in the development of this product, since these devices operate on a bedside table. This project will enable the acoustic performance of these small irregularly ....Prediction and optimisation of the acoustic performance of mufflers for sleep apnea devices. ResMed is a world leader in the technology of developing products for treating obstructive sleep apnea (OSA). ResMed provided the first successful non-invasive treatment of OSA with their sleep apnea device. Noise reduction is an important issue in the development of this product, since these devices operate on a bedside table. This project will enable the acoustic performance of these small irregularly shaped mufflers to be reliably predicted and optimised. The successful outcomes will improve the quality of the well-being of the user. This research also has relevance to the design of mufflers for use in broader applications such as locomotives and ferries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989859
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
A Multi-Resolution X-ray Microtomography Facility (NanoCT & MicroCT) for Non-Destructive 3D Characterisation. X-ray microtomography platforms are applicable to a wide diversity of research across many of the national research priority areas. The research outlined will provide insights into bone cancer and osteoporosis, promote breakthroughs in the understanding of tumour biology and drive new developments in novel biomaterials, all of which have significant national health benefits. In dentistr ....A Multi-Resolution X-ray Microtomography Facility (NanoCT & MicroCT) for Non-Destructive 3D Characterisation. X-ray microtomography platforms are applicable to a wide diversity of research across many of the national research priority areas. The research outlined will provide insights into bone cancer and osteoporosis, promote breakthroughs in the understanding of tumour biology and drive new developments in novel biomaterials, all of which have significant national health benefits. In dentistry, research supported by this instrumentation will provide Australians with improvements to their dental health. Furthermore applications to industrial materials are providing Australian industries with better characterisation of their products that is leading to improved export performance and consequent improvement in Australia's balance of trade.Read moreRead less
Development of Acid Degradable Polymeric Nanoparticles for Intracellular and Tumour Site Selective Delivery of Drugs. There is an enormous need to develop effective anticancer drug delivery systems to reduce the social and economic impact of cancer. One of the most critical problems in tumour treatment is the lack of selective toxicity of anticancer drugs against tumour tissues. Our multidisciplinary team will aim to develop a novel polymer based system for tumour site-selective delivery of anti ....Development of Acid Degradable Polymeric Nanoparticles for Intracellular and Tumour Site Selective Delivery of Drugs. There is an enormous need to develop effective anticancer drug delivery systems to reduce the social and economic impact of cancer. One of the most critical problems in tumour treatment is the lack of selective toxicity of anticancer drugs against tumour tissues. Our multidisciplinary team will aim to develop a novel polymer based system for tumour site-selective delivery of anticancer drugs. Development of such advanced drug delivery systems will significantly enhance Australia`s power in biotechnology. Development and/or formation of strategies to improve the health quality of Australians, is an important anticipated outcome of this innovative project.Read moreRead less