Quality Of Life And Arm Symptoms Following Axillary Surgery For Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$32,003.00
Summary
The aim of this project is determine how best to measure, analyse and compare the effects of different operations for women with breast cancer. This will be done with information on measurements of arm swelling, symptoms, functions, and other aspects of quality of life collected in over 1,000 women taking part in a national randomised trial. This research will provide important information about the effects of these operations, and about how best to design future surgical trials.
Molecular Determinants Of Therapeutic Response In Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$87,646.00
Summary
Colorectal cancer (CRC) is the second most common cause of cancer death. We will examine whether treatments of advanced CRC can be optimized by (1) selection based on the patient's expression of biomarkers (ie. cancer proteins) and-or (2) appropriate combinations of chemotherapy and-or immunotherapy. Using samples from patients we aim to determine predictors of response to a single therapy (bevacizumab) or a novel combination of therapies (erlotonib and cetuximab) to enhance future treatments.
The Impact Of Evidence Based Guidelines And Standardisation Of Clinical Practice Upon Patient Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$32,003.00
Summary
Over the last decade there has been a significant move toward evidence based clinical care and clinical guidelines in medical care. Despite this movement there are numerous clinical situations where evidence for any treatment is scant and where large gaps between the evidence and current practice exist. My research seeks to explore the barriers that exist in the health system that impede the uptake of evidence into practice and methods to improve patient outcomes where the evidence is poor.
Epidemiology, Diagnosis And Treatment Of Orthopaedic Infections
Funder
National Health and Medical Research Council
Funding Amount
$93,655.00
Summary
Orthopaedic surgery has led to significant improvements in patient's quality of life. With an ageing population, the number of patients requiring joint replacement and other bone and joint surgery will increase exponentially. Infection of the joint replacement is a devastating complication of this surgery. Research into these infections is still evolving. This research proposal aims to examine the clinical features of bone and joint infections, to explore ways to optimise diagnosis and improve t ....Orthopaedic surgery has led to significant improvements in patient's quality of life. With an ageing population, the number of patients requiring joint replacement and other bone and joint surgery will increase exponentially. Infection of the joint replacement is a devastating complication of this surgery. Research into these infections is still evolving. This research proposal aims to examine the clinical features of bone and joint infections, to explore ways to optimise diagnosis and improve treatment and outcomes for patients.Read moreRead less