ADding Negative PRESSure To Improve HealING (the DRESSING Trial)
Funder
National Health and Medical Research Council
Funding Amount
$2,380,446.00
Summary
The aim of this 5-year randomised comtrolled trial is to test the clinical and cost effectiveness of vacuum dressings in reducing the incidence of surgical site infection in obese women undergoing elective and semi-urgent caesarian section. The trial will be conducted at 4 hospitals in south east Queensland. 2,100 women undergoing caesarian section will either receive a vacuum or standard surgical dressing and will be followed for 1 month after surgery.
Whiplash injury incurs a huge health burden on Australia as many people do not recover well. This project aims to implement and evaluate a Clinical Pathway of Care for whiplash injury that guides primary care providers in their assessment and treatment of people with acute whiplash. This will improve health ouctomes and recovery following the injury.
Yours and mine: development of the concept of ownership in typical children and those on the autism spectrum. From an early age we know what belongs to us and what does not - we intend to find out how our behaviours keep pace with this evolving knowledge. More important for society, we will find out if behaviours and concepts are qualitatively different in children with Autistic Spectrum Disorders (ASD), causing problems with social interactions.
The Centre for Research Excellence in Nursing Interventions for Hospitalised Patients will provide evidence to improve the nursing care of a broad range of hospitalised patients who are at risk of complications related to compromised skin integrity and poor pain/anxiety management. Systematic reviews and clinical trials will provide the basis for developing clinical practice guidelines to assist nurses in providing high quality care to the 3.5 million Australians admitted to hospital each year.
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Development of a risk assessment tool to minimise mixed metals toxicities from mine tailings. Research based on animal uptake from mine tailings is required to quantify comparative bioavailability of mixtures of metals to provide data for mine rehabilitation design during the planning stage. Such data also provides risk assessment in humans. The optimum balance is minimum environmental effects from the rehabilitated mine structure versus minimised cost through planning prior to project commencem ....Development of a risk assessment tool to minimise mixed metals toxicities from mine tailings. Research based on animal uptake from mine tailings is required to quantify comparative bioavailability of mixtures of metals to provide data for mine rehabilitation design during the planning stage. Such data also provides risk assessment in humans. The optimum balance is minimum environmental effects from the rehabilitated mine structure versus minimised cost through planning prior to project commencement. The significant cost of mining ore bodies, particularly by modern open cut methods, is the removal of rock and soil. The research on animal toxicity testings will provide a tool to more accurately detail mine rehabilitation and give quantitative indicators for closure.Read moreRead less
Preventing hospital readmissions and loss of functional ability in high risk older adults: A randomised controlled trial. Older people have higher rates of hospital admission and readmission due to complications and falls. During hospitalisation, many older people experience functional decline which impacts on their future independence. Acute hospital services comprise the largest section of health expenditure in Australia, costing $26,413 million/year. Prevention or delay of disease is known to ....Preventing hospital readmissions and loss of functional ability in high risk older adults: A randomised controlled trial. Older people have higher rates of hospital admission and readmission due to complications and falls. During hospitalisation, many older people experience functional decline which impacts on their future independence. Acute hospital services comprise the largest section of health expenditure in Australia, costing $26,413 million/year. Prevention or delay of disease is known to produce more effective use of services. This study will compare the effectiveness of innovative strategies to prevent deconditioning, functional decline and hospital readmissions. Comparative analysis of these strategies will provide information with potential to reduce costs whilst improving functional status, psychosocial well-being and independence in older peopleRead moreRead less
Comprehensive discharge-planning and in-home follow-up for older adults incorporating exercise strategies to avoid de-conditioning and reduce risk of hospital re-admission. Older people have significantly higher rates of hospital admission and length of stay than the general population and higher rates of hospital re-admission due to complications and falls. During hospitalisation, older people experience significant functional decline which impacts on their future levels of independence and qua ....Comprehensive discharge-planning and in-home follow-up for older adults incorporating exercise strategies to avoid de-conditioning and reduce risk of hospital re-admission. Older people have significantly higher rates of hospital admission and length of stay than the general population and higher rates of hospital re-admission due to complications and falls. During hospitalisation, older people experience significant functional decline which impacts on their future levels of independence and quality of life. This research aims to design, deliver and evaluate an innovative model of discharge planning and in-home exercise-based follow-up for community-living frail older people at high risk of hospital re-admission as a means of promoting health. Results should delay occurrence of disease, reduce re-admissions, and improve functional status, psycho-social well-being and patient satisfaction.Read moreRead less
Special Research Initiatives - Grant ID: SR0354474
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Metals in Medicine. Metal-based drugs account for several billion dollars of pharmaceutical sales worldwide, but proportionally much less research and development has focussed on this area than organic drugs. Australia has played a pivotal role in the early development of metal-based pharmaceuticals, which remains a research strength. The dual aims of the initiative are to provide a network for a vibrant industry based around metals in medicine and to improve the health of Australians. The ini ....Metals in Medicine. Metal-based drugs account for several billion dollars of pharmaceutical sales worldwide, but proportionally much less research and development has focussed on this area than organic drugs. Australia has played a pivotal role in the early development of metal-based pharmaceuticals, which remains a research strength. The dual aims of the initiative are to provide a network for a vibrant industry based around metals in medicine and to improve the health of Australians. The initiative will foster national and international cross-disciplinary collaborations to address the impediments holding back Australia's potential to take full advantage of our research strength in metals in medicine.Read moreRead less