Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Reducing The Greatest Uncertainty In Radiotherapy.
Funder
National Health and Medical Research Council
Funding Amount
$594,197.00
Summary
The weakest link in radiotherapy is defining treatment volumes (contouring). Lack of accuracy and consistency in clinical trial contouring has been shown to result in reduced patient outcomes. Manual review of contouring is resource intensive, expensive and for advanced treatments unachievable in a timely fashion. We will assess an automated approach to contouring assessment using 4 clinical trial datasets, changing practice for future studies and enabling consistent assessment in the clinic.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100053
Funder
Australian Research Council
Funding Amount
$358,031.00
Summary
A national facility for the analysis of pyrogenic carbon. This project aims to develop a national facility for pyrogenic carbon analysis. Pyrogenic carbon is a poorly constrained, slow-cycling terrestrial carbon pool with significant carbon sequestration potential. The project expects to expand the newly developed hydrogen pyrolysis analytical capability to provide high throughput, robust measurement of the abundance and isotope composition of pyrogenic carbon in soils and sediments. This will p ....A national facility for the analysis of pyrogenic carbon. This project aims to develop a national facility for pyrogenic carbon analysis. Pyrogenic carbon is a poorly constrained, slow-cycling terrestrial carbon pool with significant carbon sequestration potential. The project expects to expand the newly developed hydrogen pyrolysis analytical capability to provide high throughput, robust measurement of the abundance and isotope composition of pyrogenic carbon in soils and sediments. This will provide significant benefit, such as the ability to make significant advances in areas as diverse as geochronology, archaeology, palaeoecology, soil science geomorphology and carbon cycle/sequestration science.Read moreRead less
Slicing India: a new perspective for understanding contemporary India. This project exploits techniques of slice history, pioneered in AUSTRALIANS: A HISTORICAL LIBRARY. Using the 12-yearly religious festival, the Kumbh Mela, to define its slice years, the study compares over time the extent to which men and women were involved with, or divorced from, the ideas of an Indian nation, political decision-making and institutions, religious practices, a wider economy and the ecology of their dwelling ....Slicing India: a new perspective for understanding contemporary India. This project exploits techniques of slice history, pioneered in AUSTRALIANS: A HISTORICAL LIBRARY. Using the 12-yearly religious festival, the Kumbh Mela, to define its slice years, the study compares over time the extent to which men and women were involved with, or divorced from, the ideas of an Indian nation, political decision-making and institutions, religious practices, a wider economy and the ecology of their dwelling places. The Project aims to identify neglected aspects of politics and society in modern India and thus sharpen understanding of India's current condition and potential.Read moreRead less
Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and aga ....Improving determinants of Australian sports talent identification and development: a multi-disciplinary approach. Sport is important to many Australians. Our sport successes enhance our national identity, generate community pride and attract mega sport events. Currently our sport talent identification and development (TID) systems have been surpassed by our international rivals who borrowed from and improved our knowledge. This project will help regain Australia's international advantage and again make Australian TID the international benchmark. Results will highlight the role of TID practices in improving recreational participation and maximising, attracting, developing and retaining sport talent. This will result in improved use of sports limited TID funding by providing greater understanding of factors that influence elite selection and sport development.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560732
Funder
Australian Research Council
Funding Amount
$114,036.00
Summary
Australian Policy Online Enhancement Project. Australian Policy Online is Australia's only comprehensive gateway providing access to research reports available electronically from nearly 120 Australian research centres and other organisations. This project will broaden the range of material available, providing important new resources to users of the site, reinforcing the site's role in the national information infrastructure through its involvement in a number of innovative projects, and streng ....Australian Policy Online Enhancement Project. Australian Policy Online is Australia's only comprehensive gateway providing access to research reports available electronically from nearly 120 Australian research centres and other organisations. This project will broaden the range of material available, providing important new resources to users of the site, reinforcing the site's role in the national information infrastructure through its involvement in a number of innovative projects, and strengthening APO's international dimension. APO will be a series of datasets comparing Australia's policy performance with other OECD countries, an annotated bibliography of hard-copy material and a series of opinion surveys; these resources are not available from other online sources.Read moreRead less
Linking soil acidification with carbon dynamics in Australian agroecosystems. The ability to mitigate climate change by sequestering soil carbon may be limited in acidic soils, which are prevalent in Australia. The project will investigate the link between carbon cycling, soil acidification and liming, and provide important knowledge to identify agricultural practices which have the capacity to build soil carbon.
The impact of outdoor youth programs on positive adolescent development: an empirical evaluation. This project will seek to ensure that the nation's outdoor resources are fully utilised for the benefit of young people. Accordingly, this project will conduct the first comprehensive randomised controlled trial of a structured outdoor youth program in order to inform more strategic investment in outdoor programs to promote positive youth development.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989920
Funder
Australian Research Council
Funding Amount
$750,000.00
Summary
Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a c ....Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a current unmet need for scientists in this country and will provide cutting-edge technologies to Australian researchers so they can better detect, understand, and treat human, animal and plant diseases and the environmental impact of climate change.Read moreRead less
Pathways from Child Protection and Juvenile Justice. Almost 50% of children (10-14 year) in the Juvenile Justice (JJ) system have substantiated histories in Child Protection (CP). The vast majority of children with CP histories do not go on to offend. Other children, with no CP history, exhibit troubled behaviour and offending. The accuracy of instruments designed to identify at-risk children and adolescents will be investigated and individual and social factors that contribute to maladjustment ....Pathways from Child Protection and Juvenile Justice. Almost 50% of children (10-14 year) in the Juvenile Justice (JJ) system have substantiated histories in Child Protection (CP). The vast majority of children with CP histories do not go on to offend. Other children, with no CP history, exhibit troubled behaviour and offending. The accuracy of instruments designed to identify at-risk children and adolescents will be investigated and individual and social factors that contribute to maladjustment and offending in these populations will be identified. The identification of factors that are related to children and adolescents entering the CP and JJ systems will inform the development of targeted prevention/intervention strategies.Read moreRead less