Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic ....Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic substances. Understanding this molecular program of epithelial-immune cell-mediated sensing/repair will be essential to understand how tissue-repair processes can be driven in the lung, an organ critical for respiration and thus life.Read moreRead less
A prospective evaluation of the impact of the nurse practitioner role on emergency department service and outcomes. The local hospital emergency department (ED) is a prominent and highly utilised service in Australian communities but demand on EDs is increasing, resulting in significant service delays. This project will study the composition of ED clinical teams around Australia and their impact on improving the timeliness and quality of emergency clinical care.
Relative efficacy of self-help treatment for insomnia. This project aims to improve available non-pharmacological treatments for insomnia by determining the relative efficacy of various forms of self-help treatment compared to standard, therapist-led, treatment. Sleep disorders have serious consequences and are widespread. Drug therapies are costly and ineffective and, while psychological treatments have a well-established evidence base, they are not utilised by many. Self-help is a potential ....Relative efficacy of self-help treatment for insomnia. This project aims to improve available non-pharmacological treatments for insomnia by determining the relative efficacy of various forms of self-help treatment compared to standard, therapist-led, treatment. Sleep disorders have serious consequences and are widespread. Drug therapies are costly and ineffective and, while psychological treatments have a well-established evidence base, they are not utilised by many. Self-help is a potential solution, but has not been properly evaluated. This project will determine the efficacy of self-help, the best delivery methods, and should result in more individuals with sleep problems receiving better and cheaper help with benefits for them and society in general.Read moreRead less
Using an audit with feedback knowledge translation intervention to promote safety and quality in health care. This project will refine, and assess the utility of, a tailored audit with feedback intervention to promote reporting of medication errors in the acute care setting. The project aim is to produce an intervention that has utility, is effective in promoting medication error reporting, and has potential for adaptation to other settings and areas of clinical risk.
Integrated depression management: a trial of a new model of care in a low vision rehabilitation setting. The project will integrate depression management into Vision Australia services and evaluate the impact of this new model of care. We anticipate that this new approach will lead to sustained improvements in clients’ quality of life.
Design features for correct use of child car restraints. This project aims to minimise incorrect use of child restraints, which triple the risk of injury to children in car crashes. One in two children travelling in cars are incorrectly restrained. Using naturalistic and epidemiological studies, this project will characterise child restraint design features that minimise errors related to the real world interaction between restraint design, parents and children, and determine the effectiveness o ....Design features for correct use of child car restraints. This project aims to minimise incorrect use of child restraints, which triple the risk of injury to children in car crashes. One in two children travelling in cars are incorrectly restrained. Using naturalistic and epidemiological studies, this project will characterise child restraint design features that minimise errors related to the real world interaction between restraint design, parents and children, and determine the effectiveness of using optimally designed restraints. This research will help child restraint manufacturers to improve their products and design better child restraint systems, that reduce injury to children in crashes.Read moreRead less
Examining the complexity of communication processes across transition points from the emergency department to improve medication safety. Problems in communication contribute significantly to adverse events that lead to serious harm for Australian consumers. Recent data show medication errors account for over 25% of all adverse events, while over 50% of consumers who move across transition points have medication errors relating to their treatment regimen. Financial costs from adverse events are e ....Examining the complexity of communication processes across transition points from the emergency department to improve medication safety. Problems in communication contribute significantly to adverse events that lead to serious harm for Australian consumers. Recent data show medication errors account for over 25% of all adverse events, while over 50% of consumers who move across transition points have medication errors relating to their treatment regimen. Financial costs from adverse events are estimated at around $A2billion/year, which are likely to increase with further complexities involving consumer care. This study will result in new knowledge about communication processes to inform the development of reporting methods and strategies, which positively influence the practices of health professionals in managing medications as consumers move across different environments.Read moreRead less
Preventing Adverse Events in Hospitals. Our research will construct strategies and tools for preventing hospital adverse events and should develop knowledge and expertise about reducing care complications in high risk patients.This research has collaborating partners which are hospitals in Victoria, South Australia and Queensland. These form part of the preventative healthcare network with implications for the nation's social and economic fabric through their role in reducing morbidity, mortali ....Preventing Adverse Events in Hospitals. Our research will construct strategies and tools for preventing hospital adverse events and should develop knowledge and expertise about reducing care complications in high risk patients.This research has collaborating partners which are hospitals in Victoria, South Australia and Queensland. These form part of the preventative healthcare network with implications for the nation's social and economic fabric through their role in reducing morbidity, mortality and supporting the health of all Australians. Since acquired complications have comparable costs to the healthcare system as that of all other forms of injury combined, there will be substantial benefits to hospitals through reduced costs.Read moreRead less
A Public Health Framework of Effectiveness: Evaluating the Framework for Telephone Counselling. The demand for telephone counselling is strong and while this form of counselling has face validity, there is no substantive research into its effectiveness for clients. This project aims to adapt the public health model to evaluate processes and outcomes of Lifeline - a generic telephone counselling service in Melbourne. The public health model of effectiveness, will, in turn, also be evaluated.
Social networks, identity and recovery. Relapse rates for alcohol and drug dependence are high, with limited understanding of what factors promote abstinence and wellbeing over the longer term. To address this gap, the proposed project will systematically examine the role of social networks and group memberships on recovery from drug dependence. In a world’s first, this project will examine whether individuals who successfully recover undergo a social identity transformation, and if so, how this ....Social networks, identity and recovery. Relapse rates for alcohol and drug dependence are high, with limited understanding of what factors promote abstinence and wellbeing over the longer term. To address this gap, the proposed project will systematically examine the role of social networks and group memberships on recovery from drug dependence. In a world’s first, this project will examine whether individuals who successfully recover undergo a social identity transformation, and if so, how this occurs. Novel insights from this project will inform our understanding of how individuals recover from addiction, with opportunities for informing current treatment approaches and developing innovative interventions. Read moreRead less