Development Of Diagnostic Tools To Characterise Predictors Of Therapeutic Outcome In Severe Constipation
Funder
National Health and Medical Research Council
Funding Amount
$433,999.00
Summary
This project will use fibre-optic technology to create detailed high resolution maps of colonic motor patterns in both health and in patients with severe constipation. The data will be used in combination with actual patient symptoms to help identify specific markers of disease that can differentiate sub-types of constipation and ultimately guide and improve treatment in constipated patients
The prevalence and cross-cultural comparison of daytime sleepiness in adolescents. International research shows many teenagers have problems falling asleep and being sleepy during the day. This can be due to an irregular sleep pattern of insufficient sleep on school nights, and sleeping-in on weekends. These problems lead to poor outcomes, including poor school performance and negative moods. The aims of the project are to measure the extent of sleep problems in Australian teenagers and compare ....The prevalence and cross-cultural comparison of daytime sleepiness in adolescents. International research shows many teenagers have problems falling asleep and being sleepy during the day. This can be due to an irregular sleep pattern of insufficient sleep on school nights, and sleeping-in on weekends. These problems lead to poor outcomes, including poor school performance and negative moods. The aims of the project are to measure the extent of sleep problems in Australian teenagers and compare these to adolescents in the United States. Detection of teenager sleep problems in Australia could lead to significant community awareness and school policy developments as it has in the United States. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101174
Funder
Australian Research Council
Funding Amount
$443,154.00
Summary
Harnessing life-course transitions to optimise time-use behaviour habits. At every stage of life, how we use our time is one of the greatest determinants of our happiness, productivity, social wellbeing and quality of life. Time-use habits, for better or worse, are entrenched in daily routines that are difficult to break. This project aims to use existing population datasets to identify when during their life people are most likely to change their time-use habits, and to describe who may be at g ....Harnessing life-course transitions to optimise time-use behaviour habits. At every stage of life, how we use our time is one of the greatest determinants of our happiness, productivity, social wellbeing and quality of life. Time-use habits, for better or worse, are entrenched in daily routines that are difficult to break. This project aims to use existing population datasets to identify when during their life people are most likely to change their time-use habits, and to describe who may be at greatest risk of making unfavourable changes (e.g., replacing physical activity with sedentary time, not getting enough sleep). Expected outcomes include new analytical methods to understand time-use routines and new knowledge to inform future time-use improvement strategies to enable Australians to live their best life.Read moreRead less
Approach To Address Socioeconomic Inequality In Oral Health
Funder
National Health and Medical Research Council
Funding Amount
$773,033.00
Summary
This research program is expected to contribute to filling significant gaps in the understanding of factors determining the oral health of Australian preschool children. The inter-relationship between factors potentially important for child oral health and their effect on oral health will be evaluated. The findings will help to re-evaluate the effectiveness and safety of oral health preventive programs used for children and to explain inequality in oral health of children.
Novel Interventions To Address Methamphetamines In Aboriginal Communities, Including A Randomised Trial Of A Web Based Therapeutic Tool Used To Treat Dependence In Clinical Settings.
Funder
National Health and Medical Research Council
Funding Amount
$2,177,908.00
Summary
Methamphetamine use in Aboriginal communities has gained much media attention, despite limited research studies to ascertain the full extent of its use and its impact. We propose a randomised trial of a web based therapeutic tool for use in Aboriginal Medical Services to treat clients using methamphetamines. In addition we will characterise the health and well-being of Aboriginal people who use methamphetamines and trial unique Aboriginal community led interventions to address methamphetamines.
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Delivering Effective Dental Healthcare In 2020-2030: A National Longitudinal Partnership Study Of Burden Of Oral Diseases In Australia
Funder
National Health and Medical Research Council
Funding Amount
$1,056,522.00
Summary
The proposed partnership project will focus on five main areas: 1. The evaluation of changes in oral diseases. 2. The assessment of the incidence of oral diseases and its relationships with service systems and individual healthcare behaviours. 3. The estimation of the burden of oral diseases in the period 2020–30. 4. The assessment of cost-effectiveness of the various patterns of dental service use. 5. The knowledge translation involving policymakers and dental service providers.
A Population-based Record Linkage Study Of The Impact Of Chlamydia Infection On Reproductive Health In Women
Funder
National Health and Medical Research Council
Funding Amount
$405,114.00
Summary
Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Au ....Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Australia.Read moreRead less
Families with multiple and complex needs: refocusing on early intervention. Families with multiple and complex needs have been determined to be a priority group in Australia (National Child Protection Framework 2021-31). This study will fill the evidence gap by determining the typologies of families with multiple and complex needs and child protection involvement who face intersecting risk factors (e.g. family violence, mental health, intergenerational trauma, alcohol/drug use, justice involveme ....Families with multiple and complex needs: refocusing on early intervention. Families with multiple and complex needs have been determined to be a priority group in Australia (National Child Protection Framework 2021-31). This study will fill the evidence gap by determining the typologies of families with multiple and complex needs and child protection involvement who face intersecting risk factors (e.g. family violence, mental health, intergenerational trauma, alcohol/drug use, justice involvement, disability, poverty and housing insecurity). Intergenerational (child and parent) linked data in three states will be utilised to investigate these families longitudinal trajectories of system involvement and to identify opportunities for enhanced prevention, points of early intervention and service planning. Read moreRead less
A Longitudinal Study Of Psychopathology In People With Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$999,803.00
Summary
This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combina ....This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combination of questionnaire survey and in depth interviews of the young adults and their families or carers to track the course of their mental health. The study commenced in 1990 with nearly 1000 young people with ID aged 4-18 years and their progress has been reviewed every 2-3 years in over 75% of the original group. During the next 5 years we plan to follow their mental health during the critical stage of young adult life. During this time there is the greatest risk of mental illnesses such as depression and schizophrenia and the stresses of adjusting to new daily occupations, independent living or residential care and social contact away from the family. We will be able to study the specific emotional and behavioural problems faced by young adults with the main known causes of ID such as Down, Fragile X, Prader Willi and William Syndromes, as well as those who have autism. The great benefit of a long term follow up study is that it allows us to study the links between earlier family environmental, psychological and biological factors and subsequent mental health problems. We can also demonstrate the impact that mental illness in a young person with ID has on the family and parental mental health. The findings have implications for better diagnosis, improved care and management, early intervention and prevention of these common severe and under recognized mental health problems in this disadvantaged group of young Australians and their families and carers.Read moreRead less