Discovery Early Career Researcher Award - Grant ID: DE190100641
Funder
Australian Research Council
Funding Amount
$422,079.00
Summary
Brillouin microscopy for high-speed imaging of rigidity within cells. This project aims to improve the sensitivity and speed of Brillouin microscopes. Brillouin microscopes use light to measure the stiffness of samples in 3D without requiring physical access, allowing their use in inaccessible locations such as the interior of cells or within intact tissue. However, Brillouin microscopes are too slow to be used in most research. This project introduces a new approach based on different optical p ....Brillouin microscopy for high-speed imaging of rigidity within cells. This project aims to improve the sensitivity and speed of Brillouin microscopes. Brillouin microscopes use light to measure the stiffness of samples in 3D without requiring physical access, allowing their use in inaccessible locations such as the interior of cells or within intact tissue. However, Brillouin microscopes are too slow to be used in most research. This project introduces a new approach based on different optical physics that is expected to enable faster and more precise imaging. The microscope will be used to study the movement of amoeba, where it is expected to reveal the controlled stiffening and fluidising of the different regions of protoplasm believed to underlie the cell mobility.Read moreRead less
Precision measurement to test fundamental physics. This project gives the University of Western Australia the opportunity to lead some of the world's best tests on fundamental physics by implementing their novel precision technology. It will also strengthen their collaboration between elite metrological institutes, including Paris Observatory, Ecole Normale Superior and Humboldt University.
Advanced eyesafe Er:YAG short pulsed lasers for remote sensing applications. This project will develop state-of-the-art tunable pulsed Er:YAG laser systems that will represent a significant advance for eyesafe remote sensing and range finder technologies. It will render obsolete, current state-of-the-art systems for laser ranging and enable remote sensing of a critical greenhouse gas.
Discovery Early Career Researcher Award - Grant ID: DE170100088
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Self-calibrating quantum devices. This project aims to improve control over quantum systems. It will develop self-calibrating quantum devices, the equivalent of Noise Cancelling Headphones for quantum systems. The project will create filtering protocols, suppressing characterised noise via appropriate controls. This is expected to lead to greater control over systems, demanded by quantum computers and nano devices, like next generation computer chips.
Plasmonic nano-antennas for next-generation photon sources. Extending concepts from standard radio-frequency antenna technology down to the nanoscale will open up new applications in fields from biotechnology to telecommunications. This project will embed a light emitting particle in a nanostructured metallic device to produce an ultrabright, directional single-photon source.
Discovery Early Career Researcher Award - Grant ID: DE120101504
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Nano-resolution hard x-ray diffraction imaging with conventional laboratory sources. The project will combine advanced optics and algorithms for diffraction imaging to develop a desktop hard x-ray microscope. The system will display ultra-high resolution and will be highly complementary to electronic and optical microscopies for diverse applications in materials engineering, nanofluidics and cell biology.
Outmaneuvering correlated noise in quantum computers. The project aims to characterise and control quantum machines available today. These machines overwhelmingly suffer from noise with complex structures. Thus, a key target of the project is to develop a theory to describe and manipulate complex quantum processes. The project then intends to apply this theory to commercial-grade quantum computers. This approach is anticipated to lead to a new understanding of time-correlated complex quantum pro ....Outmaneuvering correlated noise in quantum computers. The project aims to characterise and control quantum machines available today. These machines overwhelmingly suffer from noise with complex structures. Thus, a key target of the project is to develop a theory to describe and manipulate complex quantum processes. The project then intends to apply this theory to commercial-grade quantum computers. This approach is anticipated to lead to a new understanding of time-correlated complex quantum processes and develop methods to enhance the performance of today's quantum computers. Noise characterisation and mitigation should have commercial value and benefit research groups working to develop quantum technologies, both in Australia and internationally.Read moreRead less
Complex quantum dynamics for technological applications. This project aims to characterise dynamics of a quantum system immersed in a complex surrounding, such as a quantum computer interacting with an environment that remembers the computer’s past. Since there are no known methods for battling the effects of the environment on the computer when they are intertwined, this project will develop tools to combat these adverse effects. The project will discover physics of complex dynamics and investi ....Complex quantum dynamics for technological applications. This project aims to characterise dynamics of a quantum system immersed in a complex surrounding, such as a quantum computer interacting with an environment that remembers the computer’s past. Since there are no known methods for battling the effects of the environment on the computer when they are intertwined, this project will develop tools to combat these adverse effects. The project will discover physics of complex dynamics and investigate unexplored physical phenomena in the laboratory, like an antenna of photosynthetic systems that use complex surroundings for efficient and fast energy transport. The project is expected to help build new and improved quantum machines.Read moreRead less
Dual nanoparticles to distinguish between right and left biomolecules. This project aims to enhance the sensitivity of optical activity to ultralow molecular concentration samples. Optical activity is a commercially available technique used to distinguish chemically identical and morphologically different biomolecules (enantiomers). Unlike other scattering techniques, near-field enhancing of optical activity has not been achieved, thus limiting these measurements to high molecular concentrations ....Dual nanoparticles to distinguish between right and left biomolecules. This project aims to enhance the sensitivity of optical activity to ultralow molecular concentration samples. Optical activity is a commercially available technique used to distinguish chemically identical and morphologically different biomolecules (enantiomers). Unlike other scattering techniques, near-field enhancing of optical activity has not been achieved, thus limiting these measurements to high molecular concentrations. There is evidence indicating that optical activity can be enhanced using dual nanoparticles (ie small particles with the same response to electric and magnetic fields). This project aims to advance our understanding of these dual nanoparticles and experimentally implement their use to enhance optical activity.Read moreRead less
Neural mechanisms of water flow perception and spatial integration. This project aims to develop a novel zebrafish platform for elucidating the circuits that mediate lateral line perception. The sensory modality by which fish detect and respond to water flow is poorly understood. This project proposes a novel preparation in the zebrafish model for applying controlled water flow using microfluidics, thereby stimulating the lateral line. Because the animal remains stationary, it is possible to per ....Neural mechanisms of water flow perception and spatial integration. This project aims to develop a novel zebrafish platform for elucidating the circuits that mediate lateral line perception. The sensory modality by which fish detect and respond to water flow is poorly understood. This project proposes a novel preparation in the zebrafish model for applying controlled water flow using microfluidics, thereby stimulating the lateral line. Because the animal remains stationary, it is possible to perform whole-brain calcium imaging of cells and circuits that respond to water flow, and to use optogenetics to stimulate or silence these neurons. This will reveal the circuitry mediating flow perception, and its relationship with other senses, in a way that has been previously impossible.Read moreRead less