Cell–fluid interaction: inside and outside cells. The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened under ....Cell–fluid interaction: inside and outside cells. The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened understanding of an enigmatic process conserved from amoebae to humans, by which cells ‘drink and eat’ by ‘gulping’ fluid and supplement their nutrient intake by degrading proteins and cell debris. It will generate new knowledge of these processes to better understand how mechanics affects cellular life.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100194
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met th ....Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met through the combined use of state-of-the-art flow visualisation, thermography and spectrometry equipment. These diagnostics would open avenues into so far impossible or difficult to conduct research on highly transient phenomena in various research fields, which include various aspects of fluid mechanics, combustion, and fracture mechanics. The equipment would be instrumental in the design of better and innovative machines, materials, instruments and processes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102352
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Three-dimensional structural imaging in optical microscopy and tomography. This project will develop fundamentally new strategies for looking inside live cells to determine their internal structures. Such capability will permit a better understanding of diseases, the link between diabetes and heart failure for example, opening the door for new diagnostic techniques and treatments.
Enhancing the science reach of second generation interferometric gravitational wave detectors through innovative mirror design and control. Predicted by Einstein, gravitational waves promise to unlock the secrets of the universe just as seismic measurements unlocked the secrets of the Earth's interior. Scientists are on the brink of detecting these waves. This research aids that effort by developing Australian technologies which allow specific gravitational wave sources to be targeted.
A versatile optical wavelength and mode switching device for future telecommunication networks. This project will develop a next generation switching device for future fibre optical communication networks that will divide their information among several modes of specialty fibre. This device will be a key component for allowing network operators to move to these novel mode-multiplexed networks in order to overcome the looming capacity crunch.
Australian Laureate Fellowships - Grant ID: FL150100019
Funder
Australian Research Council
Funding Amount
$3,041,282.00
Summary
Precision laser levitation for quantum metrology and gravitational sensing. Precision laser levitation for quantum metrology and gravitational sensing: This fellowship project aims to levitate macroscopic objects using only laser beams, to provide a new tool to test physics theories. Strong laser beams can exert sufficient force to counteract gravity and make an object levitate. In contrast to other forms of levitation, laser levitation is scatter-free and can preserve system coherence. It has s ....Precision laser levitation for quantum metrology and gravitational sensing. Precision laser levitation for quantum metrology and gravitational sensing: This fellowship project aims to levitate macroscopic objects using only laser beams, to provide a new tool to test physics theories. Strong laser beams can exert sufficient force to counteract gravity and make an object levitate. In contrast to other forms of levitation, laser levitation is scatter-free and can preserve system coherence. It has superior optical and mechanical quality factors and complete information of the system dynamics is retained. This allows laser levitation to be turned into a highly controllable and ultra-sensitive device capable of detecting minute environmental changes. This research aims to probe the relationship between quantum and gravitational physics and develop laser levitation into a precision instrument for the sensing of gravity. Laser levitation has the potential to be developed into technology for mineral exploration and environmental sensing.Read moreRead less
Coherent Laser Levitation for Precision Sensing and Enabling Science. When light collides with matter, it may exert a force called radiation pressure. This project aims to use radiation pressure to levitate a small mirror. Using a tripod of laser beams, it is possible to levitate and trap the mirror in a stable position. Radiation pressure has been used before to levitate, but previous work has always involved scattering light from the levitating object. This project proposes the use of a high q ....Coherent Laser Levitation for Precision Sensing and Enabling Science. When light collides with matter, it may exert a force called radiation pressure. This project aims to use radiation pressure to levitate a small mirror. Using a tripod of laser beams, it is possible to levitate and trap the mirror in a stable position. Radiation pressure has been used before to levitate, but previous work has always involved scattering light from the levitating object. This project proposes the use of a high quality mirror, allowing the collection of the reflected light and the accurate measurement and control of the position of the mirror as it floats on the laser beams. Using the unique properties of the floating mirror, it will be possible to search for signatures of quantum gravity and develop tools for ultra-precision metrology.Read moreRead less
Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understandi ....Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understanding of cells, the building blocks of life. We will achieve this by: 1. Developing a microscope that combines microscopic resolution with rapid imaging; 2: Developing the capability to image both within the cell and its surrounding environment; and 3. Using our microscope to make discoveries in biology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100972
Funder
Australian Research Council
Funding Amount
$382,462.00
Summary
Reaching deeper into neuronal networks using optical physics. Understanding the functions and intricacies of the brain is a fundamental challenge in scientific research. This project aims to develop new technologies to construct a microscope able to alter and make sense of neuronal activity in situ. This project also aims to investigate the precise role of a key brain region involved in sensory processing: the locus coeruleus. The results will reveal how this brain region influences brain dynami ....Reaching deeper into neuronal networks using optical physics. Understanding the functions and intricacies of the brain is a fundamental challenge in scientific research. This project aims to develop new technologies to construct a microscope able to alter and make sense of neuronal activity in situ. This project also aims to investigate the precise role of a key brain region involved in sensory processing: the locus coeruleus. The results will reveal how this brain region influences brain dynamics as well as behaviour. Expected outcomes include state of the art microscopes, high impact publications, and international collaborations. The anticipated benefits are the high quality training of the Australian workforce and further establishment of Australia as a leader in microscopy and neuroscience.Read moreRead less
Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated t ....Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated that these new atomic sensors will support a global network looking for dark matter, which although never seen, is thought to make up 85% of the mass of the universe. The outcomes are expected to benefit medical science, geo-exploration, high-tech manufacturing, navigation and our understanding of the universe.Read moreRead less