Benefits And Safety Of IRon Supplementation With MAlaria Chemoprevention To Children In Malawi (IRMA) - A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$3,064,309.00
Summary
Anaemia and malaria frequently coexist in low income settings e.g. sub-Saharan Africa and Asia. Iron interventions aim to reduce anaemia but exacerbate malaria. We aim to test whether iron is made safe by coadministering malaria prevention, and whether these interventions improve child health outcomes especially cognitive development, while ensuring malaria resistance does not emerge.
An RCT To Promote Healthy Lifestyle Behaviours From Infancy: An Intervention To Prevent Childhood Overweight
Funder
National Health and Medical Research Council
Funding Amount
$578,631.00
Summary
In Australia, one in four school-aged children is currently overweight and childhood obesity rates are continuing to rise. In the last five years it has become clear that rates of overweight and obesity are also rapidly increasing in pre-school age children. These are issues that are of concern to health officials as well as to parents. We understand that these rising rates in fatness relate to children's diet and activity patterns, and that these patterns, once established are likely to be patt ....In Australia, one in four school-aged children is currently overweight and childhood obesity rates are continuing to rise. In the last five years it has become clear that rates of overweight and obesity are also rapidly increasing in pre-school age children. These are issues that are of concern to health officials as well as to parents. We understand that these rising rates in fatness relate to children's diet and activity patterns, and that these patterns, once established are likely to be patterns for life. To date, there has been relatively little research regarding the chance to support parents to establish the eating and activity patterns that will protect their children from the very beginning of life. This project seeks to support first-time parents to establish healthy eating and activity behaviours in their children using the highly utilised Maternal and Child Health Centres first time parents' groups. We believe that these groups will provide a strongly supportive environment in which to provide parents with strategies and knowledge for promoting healthy eating and activity patterns for their children, and in turn, promote healthy weight gain. This project will assess the effectiveness of this intervention.Read moreRead less
Diseases of the 21st century are complex with environmental and genetic causes. At the interface of these is Epigenetics - factors not specified by DNA sequence that control genes. Recent data show much of the risk associated with disease is set early in life, even during the time in the womb. The MCRI CDDE laboratory has assembled teams of researchers of diverse expertise investigating epigenetics of human development and complex disease to hopefully prevent or reverse them early in life.
Food and drink company sponsorship of children's sport: publicity or philanthropy? Currently food and beverage company sport sponsorship in Australia has not been analyzed or regulated. The proposed research will incorporate both of these neglected areas by determining current patterns of food company sponsorship and by driving new programs and policies to support sporting organisations in promoting children's health in a consistent fashion. This study will challenge commonly held assumptions an ....Food and drink company sponsorship of children's sport: publicity or philanthropy? Currently food and beverage company sport sponsorship in Australia has not been analyzed or regulated. The proposed research will incorporate both of these neglected areas by determining current patterns of food company sponsorship and by driving new programs and policies to support sporting organisations in promoting children's health in a consistent fashion. This study will challenge commonly held assumptions and social norms relating to the value of food company sponsorship, which is classically viewed as good corporate behaviour, but may in fact have adverse health effects.Read moreRead less
Exploring resilience in relation to physical activity and dietary behaviours among children from neighbourhoods of low socioeconomic position. The link between social disadvantage and poor health, across a broad age range, is a serious public health challenge. Current interventions to promote healthy weight-related behaviours among young people ignore the motivators and barriers unique to demographic sub-groups, and are largely ineffective. The personal and socio-environmental correlates of heal ....Exploring resilience in relation to physical activity and dietary behaviours among children from neighbourhoods of low socioeconomic position. The link between social disadvantage and poor health, across a broad age range, is a serious public health challenge. Current interventions to promote healthy weight-related behaviours among young people ignore the motivators and barriers unique to demographic sub-groups, and are largely ineffective. The personal and socio-environmental correlates of healthy behaviours among young South Australians identified in this study are likely to be relevant to low socioeconomic neighbourhoods in other states and territories. As such, this study will offer new insights into intervention design that will give impetus to the efforts of researchers, policy makers and practitioners throughout Australia.Read moreRead less
Healthy infant and young child diets from sustainable first-food systems. Breastfeeding, breastmilk and other first foods consumed during infancy and early childhood, are currently neglected in food systems research and policy action, despite their importance to establishing life-long dietary preferences, health and sustainability. This project addresses this gap, by developing a novel 'first-food systems' conceptual framework, describing global, regional and national changes in infant and young ....Healthy infant and young child diets from sustainable first-food systems. Breastfeeding, breastmilk and other first foods consumed during infancy and early childhood, are currently neglected in food systems research and policy action, despite their importance to establishing life-long dietary preferences, health and sustainability. This project addresses this gap, by developing a novel 'first-food systems' conceptual framework, describing global, regional and national changes in infant and young child diets, and generating end-user knowledge to generate political commitment for early-life nutrition. This research will deliver economic, social and environmental benefits for Australia and international communities, by helping to reduce the ill-health and environmental harms linked with unhealthy early-life diets.Read moreRead less
Maternal mental health and anaemia as determinants of infant health and development in resource constrained settings. A healthy start to life is an explicit Australian priority. Maternal health is a major determinant of the health and development of infants. This international collaborative project will contribute evidence about two maternal health conditions: mental disorders and anaemia, and their effects on infant health and development, through research in Vietnam where both are prevalent. ....Maternal mental health and anaemia as determinants of infant health and development in resource constrained settings. A healthy start to life is an explicit Australian priority. Maternal health is a major determinant of the health and development of infants. This international collaborative project will contribute evidence about two maternal health conditions: mental disorders and anaemia, and their effects on infant health and development, through research in Vietnam where both are prevalent. The findings will inform interventions to improve the health of mothers and infants in all resource-constrained settings, including among indigenous and refugee groups in Australia. It will advance Australia's international relations by strengthening a partnership with Viet Nam and contributing to a World Health Organization priority area. Read moreRead less
Moving from policy to practice: a randomised trial of an implementation intervention to facilitate the adoption of a statewide healthy canteen policy. This project will test the effectiveness of an intervention in supporting schools to implement a healthy canteen policy mandated by the New South Wales Government. The trial could provide a model for supporting schools to implement school health or education policies which seek to improve the wellbeing of students.
Early Nutrition, Epigenetics And Developmental Outcomes In Children.
Funder
National Health and Medical Research Council
Funding Amount
$550,093.00
Summary
Increasing evidence demonstrates that early nutrition, including in pregnancy, has long lasting programming effects on later health of children. Evidence implicates epigenetics (literally ‘above DNA’) in mediating these effects. The most convincing data exists for obesity and related disorders such as metabolic syndrome, diabetes, and heart disease. The focus of this project is on understanding how ‘epigenetic’ mechanisms are influencing the way our genes function to cause these disorders.
Understanding children's risk of obesity: contextual influences on changes in eating, physical activity and weight status. Overweight and obesity are significant public health issues in Australia. After tobacco, physical inactivity and obesity are leading modifiable contributors to the burden of disease. The economic cost of obesity was recently estimated at $1.3 billion/year. Preventing further increases in childhood obesity is an urgent national priority, however there currently exists insuffi ....Understanding children's risk of obesity: contextual influences on changes in eating, physical activity and weight status. Overweight and obesity are significant public health issues in Australia. After tobacco, physical inactivity and obesity are leading modifiable contributors to the burden of disease. The economic cost of obesity was recently estimated at $1.3 billion/year. Preventing further increases in childhood obesity is an urgent national priority, however there currently exists insufficient information to guide effective obesity prevention strategies. The findings of this study will inform efforts to prevent obesity at the population level by enhancing knowledge of contextual influences on obesity-risk behaviours and the selection of specific targets for intervention. As such, this study will help create a healthier generation of children.Read moreRead less