Design of multimodal polymeric nanoparticles as targeted carriers for the co-delivery of therapeutic molecules. This project will greatly enhance the tools available to oncologists by providing new treatment options, minimising side-effects to conventional chemotherapy approaches. In this project, the design of next generation of drug delivery will be developed using the most recent advances in materials sciences.
The role of copper in the early ubiquitination pathway. This project aims to explore the role of copper in ageing and protein turnover. The removal of damaged or excess proteins is achieved by ubiquitin-tagging in all kingdoms of life. It has recently been observed that one of the earliest steps of this process appears to be driven by copper. This project aims to elaborate the precise biochemical mechanisms by which copper regulates this important tagging and protein turnover system. It proposes ....The role of copper in the early ubiquitination pathway. This project aims to explore the role of copper in ageing and protein turnover. The removal of damaged or excess proteins is achieved by ubiquitin-tagging in all kingdoms of life. It has recently been observed that one of the earliest steps of this process appears to be driven by copper. This project aims to elaborate the precise biochemical mechanisms by which copper regulates this important tagging and protein turnover system. It proposes to characterise the structure and function of a newly identified copper-dependent form of cell enzyme which could be involved in amplifying ubiquitin-tagged protein breakdown. Copper is essential for life in all domains. Identifying copper as a major regulator in protein clearance is important in understanding this fundamental biological machinery.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL100100117
Funder
Australian Research Council
Funding Amount
$2,713,582.00
Summary
Molecular Plasmonics - From Single Electrons to Quantum Catalysis and Optical Logic Gates. After a decade of basic research, Nanotechnology is now entering its most disruptive phase. New nanoscale phenomena are being exploited and converted into viable technologies. Plasmonics - the manipulation of light using metal nanostructures - is one of the most promising of these. Plasmonics will enable scientists to achieve optical computing, reach higher data storage densities, and synthesize better cat ....Molecular Plasmonics - From Single Electrons to Quantum Catalysis and Optical Logic Gates. After a decade of basic research, Nanotechnology is now entering its most disruptive phase. New nanoscale phenomena are being exploited and converted into viable technologies. Plasmonics - the manipulation of light using metal nanostructures - is one of the most promising of these. Plasmonics will enable scientists to achieve optical computing, reach higher data storage densities, and synthesize better catalysts. Other applications include bio-sensing and rapid pathogen detection. To realise these potential outcomes, a leading international cluster focussing on plasmonics will be set up and this cluster will link state-of-the-art materials science, instrumentation and theory.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100009
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
Magnetometry Facility for Molecular and Nanoscale Materials. Advances in information and communications technology are critically dependent on increasing the capacity, speed and energy efficiency of logic and memory electronic devices. These improvements can be achieved by reducing component size to the nanoscale and using magnetic spin as well as charge. This Project aims to establish Australia's first integrated Magnetometry Facility for determining the magnetic properties of a range of nanosc ....Magnetometry Facility for Molecular and Nanoscale Materials. Advances in information and communications technology are critically dependent on increasing the capacity, speed and energy efficiency of logic and memory electronic devices. These improvements can be achieved by reducing component size to the nanoscale and using magnetic spin as well as charge. This Project aims to establish Australia's first integrated Magnetometry Facility for determining the magnetic properties of a range of nanoscale materials down to the level of individual nanomagnets. The Facility will provide crucial characterisation capabilities for Australian researchers, building capacity to develop new magnetic nanomaterials and devices for high-density data storage, quantum computing and spintronics.
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Discovery Early Career Researcher Award - Grant ID: DE200101076
Funder
Australian Research Council
Funding Amount
$426,985.00
Summary
Resolving nanoscale structure-activity for rational electrocatalyst design. This project aims to investigate the structural and functional properties of electrocatalysts at the nanoscale. The project expects to develop state-of-the-art electrochemical imaging technology that can examine the active sites of electrodes during operation. Understanding electrode performance on this scale is expected to enhance our capability to rationally design cheaper and more-efficient electrocatalysts, notably ....Resolving nanoscale structure-activity for rational electrocatalyst design. This project aims to investigate the structural and functional properties of electrocatalysts at the nanoscale. The project expects to develop state-of-the-art electrochemical imaging technology that can examine the active sites of electrodes during operation. Understanding electrode performance on this scale is expected to enhance our capability to rationally design cheaper and more-efficient electrocatalysts, notably for electrochemical carbon dioxide reduction. This should provide significant socio-economic and environmental benefits, through the development of next-generation energy storage and conversion materials that can be utilized by households and businesses to store renewable energy in the form of carbon-neutral fuels.Read moreRead less
The Quantum Dot SPASER. Can we replace electrons with photons in future computers? This project provides two steps toward this goal. By combining advanced materials with ultra-small metallic structures, a new nano-sized form of a laser, called the spaser will be realised. Furthermore, a key component of a computer, a nanoscale modulator, will be demonstrated.
Engineering nanosheet-based novel structures. Microscopic structures will be engineered based on super thin materials, which promise to deliver significant advancements in the development of high sensitivity detectors, and efficient energy conversion and storage devices. This project will develop techniques that are not only green but also possess the flexibility to tailor-make novel structures.
Medium temperature electrolysis for low-cost carbon dioxide utilization. Carbon dioxide is a notorious greenhouse gas. Its capture, and subsequent storage or utilization, is a major focus not only for researchers, but also for governments trying to meet their obligations of the Paris Agreement on climate change and for industries managing their legal and social responsibilities. This project aims to develop commercially viable medium temperature electrolysers to convert carbon dioxide into value ....Medium temperature electrolysis for low-cost carbon dioxide utilization. Carbon dioxide is a notorious greenhouse gas. Its capture, and subsequent storage or utilization, is a major focus not only for researchers, but also for governments trying to meet their obligations of the Paris Agreement on climate change and for industries managing their legal and social responsibilities. This project aims to develop commercially viable medium temperature electrolysers to convert carbon dioxide into value added chemicals using electricity from renewable sources. New design principles will be developed to generate highly active and selective catalysts with long-term stability. These electrolyzers will be integrated with carbon capture technologies to directly utilize captured carbon dioxide with high energy efficiency.Read moreRead less
Smart materials from semi-soft particles. This project will combine precision polymer chemistry to material science to develop structured nanoparticles for applications in photonics and shape memory materials.
Discovery Early Career Researcher Award - Grant ID: DE150100427
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
All-in-one Functional Nanocrystal Inks for Printed Inorganic Solar Cells. At present, manufacturing solar panels involves expensive high temperature and high vacuum processes. The bottleneck to cheaper solar power is the ability to design new methods of manufacturing. The ability to print the active components of a solar cell is an excellent way to mitigate these costs. This project aims to focus on developing the knowledge to print the most crucial component of a solar cell - the light absorbin ....All-in-one Functional Nanocrystal Inks for Printed Inorganic Solar Cells. At present, manufacturing solar panels involves expensive high temperature and high vacuum processes. The bottleneck to cheaper solar power is the ability to design new methods of manufacturing. The ability to print the active components of a solar cell is an excellent way to mitigate these costs. This project aims to focus on developing the knowledge to print the most crucial component of a solar cell - the light absorbing layer. Innovative nanoscience will be used to develop novel solar inks composed of tiny semiconductor crystals. The formulation and transformation of these inks into efficient semiconductor light absorbing layers, with a clear view to cheaper printed solar cells, will be the key objective of this project.Read moreRead less