SILICON BASED PHOTONIC CRYSTALS FOR MONITORING BIOMOLECULAR INTERACTIONS. Two great goals of biomolecular science are to monitor biomolecular interactions in real time and with sufficient sensitivity to allow small amounts of biological material to be investigated. The achievement of these goals is limited by the methods of transducing these reactions. The aim of this multidisciplinary proposal is to overcome this limitation by developing photonic devices that exploit the unique properties of na ....SILICON BASED PHOTONIC CRYSTALS FOR MONITORING BIOMOLECULAR INTERACTIONS. Two great goals of biomolecular science are to monitor biomolecular interactions in real time and with sufficient sensitivity to allow small amounts of biological material to be investigated. The achievement of these goals is limited by the methods of transducing these reactions. The aim of this multidisciplinary proposal is to overcome this limitation by developing photonic devices that exploit the unique properties of nanoporous silicon. The hybridisation of DNA will be used as a model biorecognition reaction. Potential applications of these photonic devices are as highly sensitive affinity sensors and as tools for investigating the kinetics of biomolecular interactions.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989390
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Versatile Scanning X-ray Microscopy Facility at the Australian Synchrotron. The challenges of the modern world means that the Australian community must continue to have access to state of the art research tools. An important component of international synchrotron sources is the very high resolution x-ray microscope. These microscopes are used to image samples of biological, material or environmental significance with extraordinary precision. This project will establish such a microscope at the A ....Versatile Scanning X-ray Microscopy Facility at the Australian Synchrotron. The challenges of the modern world means that the Australian community must continue to have access to state of the art research tools. An important component of international synchrotron sources is the very high resolution x-ray microscope. These microscopes are used to image samples of biological, material or environmental significance with extraordinary precision. This project will establish such a microscope at the Australian Synchrotron in Clayton, and nucleates an extensive nationwide collaboration that is devoted to the development of this and related techniques and their application to problems of national scientific, environmental and technological importance.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989648
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australi ....Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australian researchers to achieve a major impact in many areas of Mid IR fundamental and applied science as well as industry sectors such as sensing, biophotonics, defence, health, bio-security and imaging. Read moreRead less
Quantum noise limited molecular spectrometry. This project will develop a new technology for chemical analysis using lasers. The research will produce more accurate instruments for analysing samples containing carbon dioxide and water. This technology has a surprisingly wide array of applications. For example, sensitive analysis of carbon dioxide will help law enforcement agencies identify the location of illicit drug manufacturing, test for performance enhancing drug use by elite athletes, and ....Quantum noise limited molecular spectrometry. This project will develop a new technology for chemical analysis using lasers. The research will produce more accurate instruments for analysing samples containing carbon dioxide and water. This technology has a surprisingly wide array of applications. For example, sensitive analysis of carbon dioxide will help law enforcement agencies identify the location of illicit drug manufacturing, test for performance enhancing drug use by elite athletes, and monitor greenhouse gases. The instrument for analysing water will improve water resource management in Australia. This program will result in commercial instruments that are sensitive, portable and affordable.Read moreRead less
Liquid light: aqueous bio-sensing in microstructured polymer optical fibres. This project builds on Australia's world-leading position in the development of microstructured polymer optical fibres, and applies the unique benefits they provide to for ultra- sensitive bio-sensing. By using the microstructure to simultaneously confine light and liquid, microstructured optical fibres provide a unique platform for ultra-sensitive spectroscopy and structural studies of biomolecules in solution. The wor ....Liquid light: aqueous bio-sensing in microstructured polymer optical fibres. This project builds on Australia's world-leading position in the development of microstructured polymer optical fibres, and applies the unique benefits they provide to for ultra- sensitive bio-sensing. By using the microstructure to simultaneously confine light and liquid, microstructured optical fibres provide a unique platform for ultra-sensitive spectroscopy and structural studies of biomolecules in solution. The work has profound implications both for fundamental science and applications, particularly in medical diagnostics.Read moreRead less
Hollow-core microstructured polymer fibres for optical sensing applications. A range of remarkable new optical fibres will be fabricated utilising the capabilities of a unique polymer fibre fabrication facility and focussing on the highly demanding class of microstructured fibres in which guidance in a hollow core is achieved through photonic band gap or Bragg guidance. Long lengths of low-loss fibres of this type will be developed, and applications in optical gas sensing, spectroscopy, voltage ....Hollow-core microstructured polymer fibres for optical sensing applications. A range of remarkable new optical fibres will be fabricated utilising the capabilities of a unique polymer fibre fabrication facility and focussing on the highly demanding class of microstructured fibres in which guidance in a hollow core is achieved through photonic band gap or Bragg guidance. Long lengths of low-loss fibres of this type will be developed, and applications in optical gas sensing, spectroscopy, voltage sensing and telecommunications will be explored.Read moreRead less
Tailoring the functionality of microstructured polymer optical fibres. Australia leads the world in microstructured polymer optical fibre (mPOF) research that has attracted serious commercial interest from multinational companies. A series of ATSE funded workshops in Europe during 2004 strongly indicated that the incorporation of a range of additional functionalities within novel fibres is the right path to follow to maintain research momentum and leadership. This interdisciplinary project offer ....Tailoring the functionality of microstructured polymer optical fibres. Australia leads the world in microstructured polymer optical fibre (mPOF) research that has attracted serious commercial interest from multinational companies. A series of ATSE funded workshops in Europe during 2004 strongly indicated that the incorporation of a range of additional functionalities within novel fibres is the right path to follow to maintain research momentum and leadership. This interdisciplinary project offers a clear route to expanded collaboration in both Australia and overseas thus ensuring that the OFTC retains its research and technological edge into the future whilst helping to satisfy the demand for students trained in leading-edge photonics.Read moreRead less
In vivo molecular imaging using engineered affinity reagents and fluorescent laser scanning confocal endomicroscopy. The goal of this project is to develop laser scanning confocal endomicroscopy as a tool for basic scientific discovery and rapid detection of disease biomarkers. The cutting-edge instrument and associated technologies will provide scientists with unprecedented access to dynamic biological processes as they occur in real-time. In addition, it will enable the development of virtual ....In vivo molecular imaging using engineered affinity reagents and fluorescent laser scanning confocal endomicroscopy. The goal of this project is to develop laser scanning confocal endomicroscopy as a tool for basic scientific discovery and rapid detection of disease biomarkers. The cutting-edge instrument and associated technologies will provide scientists with unprecedented access to dynamic biological processes as they occur in real-time. In addition, it will enable the development of virtual biopsies and instant diagnosis without the need for costly and time-consuming histopathological reports. Thus, it will not only drive transformative research but also transform health care delivery. It will also be a major boost to the Australian biotechnology industry with potential for enormous economic benefits.Read moreRead less
Optical Biomimetics of Diatoms. Optics is a research and economic strength of Australia. We will aim to provide a new optical sensor for chemicals using a diatom. This use of an optical device found in nature is groundbreaking and may provide a more efficient form of sensor to help to detect pollution such as metals in marine environments. Alternatively, diatoms could become the component of an iridescent paint for cars or other commercial objects. Diatoms could be made-to-measure in the laborat ....Optical Biomimetics of Diatoms. Optics is a research and economic strength of Australia. We will aim to provide a new optical sensor for chemicals using a diatom. This use of an optical device found in nature is groundbreaking and may provide a more efficient form of sensor to help to detect pollution such as metals in marine environments. Alternatively, diatoms could become the component of an iridescent paint for cars or other commercial objects. Diatoms could be made-to-measure in the laboratory on a commercial scale, and so may introduce a new industry, where other optical devices in nature could be cultured by the tonne.Read moreRead less
Integrated Photonics for Secure Communication and Related Applications in Financial Transaction Data Analysis. The project includes excellent basic science, semiconductor device fabrication and applied mathematics with explicitly identified consequences for innovation. There is strong potential for national economic benefits through the manufacture of new integrated photonic devices, the application of these devices in secure communication systems, the research of advanced non-linear analysis pr ....Integrated Photonics for Secure Communication and Related Applications in Financial Transaction Data Analysis. The project includes excellent basic science, semiconductor device fabrication and applied mathematics with explicitly identified consequences for innovation. There is strong potential for national economic benefits through the manufacture of new integrated photonic devices, the application of these devices in secure communication systems, the research of advanced non-linear analysis protocols, and the implementation of these in financial transaction analysis. Professional development and research education of postgraduate students and early career researchers will be carried out in a multi-disciplinary research environment with ongoing uptake of the research in industry and commercial sectors.Read moreRead less