Tailoring nano-crystal suspensions for extended ion supply to hydrophobic and hydrophilic leaf surfaces. Nutrient deficiency undermines the potential of billions of people and many nations. The requirement is to rapidly increase micro-nutrient delivery to support intensive and fortified crop production. This proposal seeks to develop a controlled ion release system through the use of tailored suspensions of nano-crystal nutrient materials for delivery to plants through the leaves. This will incr ....Tailoring nano-crystal suspensions for extended ion supply to hydrophobic and hydrophilic leaf surfaces. Nutrient deficiency undermines the potential of billions of people and many nations. The requirement is to rapidly increase micro-nutrient delivery to support intensive and fortified crop production. This proposal seeks to develop a controlled ion release system through the use of tailored suspensions of nano-crystal nutrient materials for delivery to plants through the leaves. This will increase yields from arable land, reduce water requirements and fertiliser applications, fortifying foods for better nutrition leading to improved human health and wellbeing. It leverages and applies recent significant advances in surface science and nanotechnology to gain improved outcomes in agriculture.Read moreRead less
Innovative green technology for bio-particle engineering. Approximately 40% of new pharmaceuticals are poorly soluble in bodily fluids. In many cases this leads to poor bioavailability, and consequent undesirable side effects as a result of high compensating dosages and generally poor patient compliance. These issues will be addressed by developing a green technology for the re-engineering of pharmaceuticals with the objective of increasing bioavilability. The research programme falls within th ....Innovative green technology for bio-particle engineering. Approximately 40% of new pharmaceuticals are poorly soluble in bodily fluids. In many cases this leads to poor bioavailability, and consequent undesirable side effects as a result of high compensating dosages and generally poor patient compliance. These issues will be addressed by developing a green technology for the re-engineering of pharmaceuticals with the objective of increasing bioavilability. The research programme falls within the Designated Research Priority of Frontier Technologies for Building and Transforming Australian Industries. Read moreRead less
Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this ....Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this project include a new fundamental understanding of the effect of mechanical properties on cell function, novel insights into the regulation of stem cell fate, and the development of a new class of roughness-tunable materials suitable for use in tissue engineering and pharmaceutical applications. Read moreRead less
Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design stand ....Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design standards for microdevice manufacture for these industries, ultimately leading to the creation of new, exciting avenues for tailoring novel biotechnology and 'point-of-care' products for Australia.Read moreRead less
Production and nano-characterisation of II-VI semiconductor quantum dots from plant cell cultures. Nanocrystallites with semiconductor properties have potential applications in medicine, microelectronics and waste treatment. Cheap, reliable methods for producing large quantities of monodisperse nanoparticles are required. Solution techniques have been used most commonly; however, production of stable, high-quality particles remains difficult. Biological synthesis using plant cell culture offers ....Production and nano-characterisation of II-VI semiconductor quantum dots from plant cell cultures. Nanocrystallites with semiconductor properties have potential applications in medicine, microelectronics and waste treatment. Cheap, reliable methods for producing large quantities of monodisperse nanoparticles are required. Solution techniques have been used most commonly; however, production of stable, high-quality particles remains difficult. Biological synthesis using plant cell culture offers several important advantages. As peptide capping is incorporated into the biological assembly process, the nanoparticles are restricted in size, their stability is improved, and their surfaces are passivated. Application of plant cultures for nanocrystallite production is a novel approach with the potential to yield significant improvements in the quality of manufactured quantum dots.Read moreRead less
Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a signific ....Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a significant improvement in diverse fields such as health care. Through this project, novel macroporous materials will be fabricated using an economically and environmentally sustainable approach. These new materials will have unique structures and properties compared to conventional macroporous materials, advancing Australia's intellectual position in this discipline.Read moreRead less
Microfluidic Studies of Stimuli-Responsive Emulsions. Breakthrough 'stimuli-responsive interface technology' has been developed in Australia to allow better control over emulsions, which are oil-in-water mixtures used widely in everyday products such as medicines. This project will increase our understanding of this new technology, by examining how the chemistry of the molecules at the interface interacts with fluid behaviour when the emulsion is made. The research will employ miniature lab-on-a ....Microfluidic Studies of Stimuli-Responsive Emulsions. Breakthrough 'stimuli-responsive interface technology' has been developed in Australia to allow better control over emulsions, which are oil-in-water mixtures used widely in everyday products such as medicines. This project will increase our understanding of this new technology, by examining how the chemistry of the molecules at the interface interacts with fluid behaviour when the emulsion is made. The research will employ miniature lab-on-a-chip systems, to give engineers and scientists design rules for this new technology, opening the way to new products that will improve our everyday lives. One immediate product to be researched is 'precision' double emulsions, which show unique properties for the delivery of chemotherapy medicines.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453823
Funder
Australian Research Council
Funding Amount
$445,124.00
Summary
Atomic Force Microscopy Facility for Soft Interfaces. This proposal seeks to establish a specialized atomic force microscopy facility capable of performing measurements on nanometre scales at soft interfaces. This will service the needs of and collaboration between leading researchers at the Universities of Newcastle, Melbourne, New South Wales and James Cook University. The facility will allow direct measurements of properties of the interactions between atoms, molecules and surfaces associated ....Atomic Force Microscopy Facility for Soft Interfaces. This proposal seeks to establish a specialized atomic force microscopy facility capable of performing measurements on nanometre scales at soft interfaces. This will service the needs of and collaboration between leading researchers at the Universities of Newcastle, Melbourne, New South Wales and James Cook University. The facility will allow direct measurements of properties of the interactions between atoms, molecules and surfaces associated with soft interfaces which are required for ongoing research in fluid-fluid interfaces, surfactant and polymer adsorbed layers, and biomolecules as well as to develop new processes in emerging fields of nanotechnology, biotechnology, and medical and pharmaceutical production.Read moreRead less
Crystalline Mesoporous Metal Oxides for Solid Oxide Fuel Cell Electrodes. Our crystalline mesoporous electrodes will help realise the full potentials of solid oxide fuel cells. Such advanced fuel cell technology will drastically increase the power generation efficiency, and reduce CO2 emissions from present power plants, thereby transforming Australian energy industry and improving our environment. The design and development of novel crystalline mesoporous materials that find widespread industri ....Crystalline Mesoporous Metal Oxides for Solid Oxide Fuel Cell Electrodes. Our crystalline mesoporous electrodes will help realise the full potentials of solid oxide fuel cells. Such advanced fuel cell technology will drastically increase the power generation efficiency, and reduce CO2 emissions from present power plants, thereby transforming Australian energy industry and improving our environment. The design and development of novel crystalline mesoporous materials that find widespread industrial applications will advance Australia's knowledge and skill base, and help Australia's high-tech industries to stay competitive, including the development of new high-tech industries in Australia.Read moreRead less
Nano- and micro-scale engineering of MoS2-based catalyst for conversion of syngas to ethanol. Domestic production of ethanol to provide a 10% blend in petrol (E10) can be achieved from waste methane gas that Australia currently vents or flares to atmosphere. This project aims to develop a conversion process for making ethanol from syngas (the product of coal or methane gasification). Small scale, modularised plants would make ethanol locally to the methane emission source. The benefits of local ....Nano- and micro-scale engineering of MoS2-based catalyst for conversion of syngas to ethanol. Domestic production of ethanol to provide a 10% blend in petrol (E10) can be achieved from waste methane gas that Australia currently vents or flares to atmosphere. This project aims to develop a conversion process for making ethanol from syngas (the product of coal or methane gasification). Small scale, modularised plants would make ethanol locally to the methane emission source. The benefits of local E10 production would be a reduction in the oil trade deficit of $1 billion per year, $500 million per year in lower carbon imposts to industry and government, 25 million tonnes per year of reduced CO2e release to atmosphere and significantly improved urban air through reduced emissions from car transport, with attendant human health benefits.Read moreRead less