Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989539
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Purchase of a state-of-the-art high resolution inductively coupled plasma mass spectrometer. This new state-of-the-art mass spectrometer with enhanced capability will allow Tasmanian researchers to accurately determine the elemental composition of their samples of interest. The instrument will be extremely sensitive and will be able to detect elements to very low concentrations. It will be used to support a diverse range of local research projects of international significance, for example the ....Purchase of a state-of-the-art high resolution inductively coupled plasma mass spectrometer. This new state-of-the-art mass spectrometer with enhanced capability will allow Tasmanian researchers to accurately determine the elemental composition of their samples of interest. The instrument will be extremely sensitive and will be able to detect elements to very low concentrations. It will be used to support a diverse range of local research projects of international significance, for example the environmental assessment of clean and contaminated sites, chemical synthesis on a miniature scale using micro-chips, and the monitoring of selected elements of key importance for human health.Read moreRead less
Atmospheric CO2, global temperature, and surface ocean acidity response to fossil carbon burning - insights from an ancient analogue. Sequestration of anthropogenic CO2 emissions by the oceans and the impacts of resulting ocean acidification and greenhouse warming upon marine ecosystems are vital to understanding the course of future environmental change. This research will improve knowledge of the biological and chemical responses in the ocean to past changes in atmospheric CO2 levels and incre ....Atmospheric CO2, global temperature, and surface ocean acidity response to fossil carbon burning - insights from an ancient analogue. Sequestration of anthropogenic CO2 emissions by the oceans and the impacts of resulting ocean acidification and greenhouse warming upon marine ecosystems are vital to understanding the course of future environmental change. This research will improve knowledge of the biological and chemical responses in the ocean to past changes in atmospheric CO2 levels and increased ocean acidity. This will assist in predicting the consequences of different fossil fuel burning scenarios for climate and marine life, especially the future viability of organisms like corals, molluscs, and calcareous plankton that underpin key tourism and marine production systems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989127
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of ....A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of option to an existing spectrometer that will broaden its user-base from specialised applications in physics to more general applications in physics, chemistry, materials-science and biology. This additional option provides a totally new way for Australian scientists to study atomic and molecular motions. Read moreRead less
Cellular and network basis of information processing in the mammalian visual system. The project aims to discover the strategies by which cells in the brain interact with each other to code the sensory input efficiently. It is expected that simultaneous recording of the activity of many neurones from the visual cortex of anaesthetised cats during visual stimulation will reveal how the biophysics of synaptic integration combined with excitatory and inhibitory inputs from different sources sculpt ....Cellular and network basis of information processing in the mammalian visual system. The project aims to discover the strategies by which cells in the brain interact with each other to code the sensory input efficiently. It is expected that simultaneous recording of the activity of many neurones from the visual cortex of anaesthetised cats during visual stimulation will reveal how the biophysics of synaptic integration combined with excitatory and inhibitory inputs from different sources sculpts the output of individual neurones. The experiments will be extended to the study of possible interactions between different areas of the brain and the study of mechanisms by which the cortical network and higher cognitive factors such as attention and memory might influence the coding of sensory information in awake animals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668100
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
High Resolution Simultaneous DSC/DTA-TGA-FTIR System. National Research Priorities including 'New Materials' 'Frontier Technologies for Building and Transforming Australian Industries' and 'Developing Deep Earth Resources' will all be addressed and the benefits will include new materials such as carbon nanotubes and layered silicate composites. It will also contribute economically through technological development, supporting existing Australian companies in the development of more effective pro ....High Resolution Simultaneous DSC/DTA-TGA-FTIR System. National Research Priorities including 'New Materials' 'Frontier Technologies for Building and Transforming Australian Industries' and 'Developing Deep Earth Resources' will all be addressed and the benefits will include new materials such as carbon nanotubes and layered silicate composites. It will also contribute economically through technological development, supporting existing Australian companies in the development of more effective products and help keep pace with new and innovative advances in technology and to bring in vitality to strategic alliances with industry already launched by the University through a Sustainable Regions Program grant titled 'Building nanotechnology business potential in the Campbelltown-Camden region'.Read moreRead less
Fluorine-labelled proteins for NMR spectroscopy. The technique developed in this project has direct impact on pharmaceutical research: NMR spectroscopy is used routinely to identify chemical compounds that bind to protein targets. This project includes the development of novel assignment techniques of 19F-labelled proteins, so that 19F-NMR can be used to detect specific binding interactions. One of the methods proposed here is designed to reveal structural information about the binding mode in s ....Fluorine-labelled proteins for NMR spectroscopy. The technique developed in this project has direct impact on pharmaceutical research: NMR spectroscopy is used routinely to identify chemical compounds that bind to protein targets. This project includes the development of novel assignment techniques of 19F-labelled proteins, so that 19F-NMR can be used to detect specific binding interactions. One of the methods proposed here is designed to reveal structural information about the binding mode in solution with atomic detail. This knowledge can significantly accelerate drug development. It is otherwise only available from crystal structures that can not always be determined.Read moreRead less
An integrated approach towards the development of new generation RF/microwave dielectric materials. The ultimate aim of this project is to rationally design and optimize new types of environmentally-sustainable, cost-effective and high performance microwave dielectric materials and devices for advanced information and communication technology (ICT) applications. This is a designated National Research Priority area. Our fundamental understanding of dielectric materials and their properties will b ....An integrated approach towards the development of new generation RF/microwave dielectric materials. The ultimate aim of this project is to rationally design and optimize new types of environmentally-sustainable, cost-effective and high performance microwave dielectric materials and devices for advanced information and communication technology (ICT) applications. This is a designated National Research Priority area. Our fundamental understanding of dielectric materials and their properties will be enhanced considerably by working on this project. Further, we will promote the relationship between the fundamental science of polar crystalline materials and practical applications. If successful, the results will enhance Australia's capacity and standing in this highly competitive area. Read moreRead less
Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be disc ....Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be discovered and then incorporated into new microwave components and/or devices developed in response to the requirements of the international wireless telecommunications market. The requested PhD student will gain experience in both the industrial and academic worlds and the skills needed to be part of Australia's high-tech workforce. Read moreRead less
TOWARDS A COMPLETE DESCRIPTION OF HOW ENZYMES WORK: development of simulation methods and protocols, blind test predictions, and experimental validation. Enzymes catalyze quite fantastic chemistry under mild physiological conditions. Many special chemical concepts (such as "transition-state stabilization" and "entropy-enthalpy compensation") proposed to explain these powers are unnecessary. Uniquely for a catalyst, these powers are integral to the structure, properties and dynamics of the protei ....TOWARDS A COMPLETE DESCRIPTION OF HOW ENZYMES WORK: development of simulation methods and protocols, blind test predictions, and experimental validation. Enzymes catalyze quite fantastic chemistry under mild physiological conditions. Many special chemical concepts (such as "transition-state stabilization" and "entropy-enthalpy compensation") proposed to explain these powers are unnecessary. Uniquely for a catalyst, these powers are integral to the structure, properties and dynamics of the protein, as constrained and selected by evolution. The question is how do they work? Answering this requires energetic and thermodynamic analysis beyond current experimental techniques, but accessible by computer simulation. We aim to develop a robust toolkit of simulation methods and protocols, blind test them by predicting the mechanism of a new enzyme, with followup experimental validation.
Read moreRead less
Wet Granular Materials: A Three-Dimensional Study Using X-Ray Microtomography. Wet granular materials are of immense economic importance in industries such as mining, agriculture, pharmaceuticals, and food processing. It has been estimated that operations involving the storage, handling and transport of granular materials account for over a third of the capital costs and over half of all the operating costs involved in process industries worldwide. An improved understanding of the dramatic effec ....Wet Granular Materials: A Three-Dimensional Study Using X-Ray Microtomography. Wet granular materials are of immense economic importance in industries such as mining, agriculture, pharmaceuticals, and food processing. It has been estimated that operations involving the storage, handling and transport of granular materials account for over a third of the capital costs and over half of all the operating costs involved in process industries worldwide. An improved understanding of the dramatic effects of liquid on the cohesion, flow and mixing of granular materials will be of benefit to Australian industry both in terms of helping to reduce costly problems, such as caking and segregation, and in terms of the development of better particulate-based products, such as ceramics and pharmaceuticals.Read moreRead less