Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Doped alumina with tailored material properties for battery applications. This project aims to develop tailored alumina materials for lithium ion battery separators through a novel in-situ approach that will: (1) produce uniform doped alumina for improved safety, (2) target specific surface and bulk material properties to increase the overall performance, and (3) reduce manufacturing costs by integrating the process with new technology developed for the production of high purity alumina. Signifi ....Doped alumina with tailored material properties for battery applications. This project aims to develop tailored alumina materials for lithium ion battery separators through a novel in-situ approach that will: (1) produce uniform doped alumina for improved safety, (2) target specific surface and bulk material properties to increase the overall performance, and (3) reduce manufacturing costs by integrating the process with new technology developed for the production of high purity alumina. Significant advances are proposed for overcoming current manufacturing limitations of doped alumina. Building research capacity and knowledge in battery material manufacturing will benefit a range of industries across Australia, whilst providing new opportunities for growth in local communities.Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. S ....Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. Significant outcomes are expected to be achieved through building fundamental understanding around this breakthrough, including new concepts for hierarchical nanomaterials based on biomolecular design, new molecular and engineering design rules for core-shell materials, and novel materials for applications in sustained release and delivery systems.Read moreRead less
Engineered nanoporous materials and composites having hierarchical structures by emulsion templating. The project aims to develop new and flexible emulsion-templated processes capable of constructing novel nanoporous materials with hierarchical structures. The project has the potential to revolutionise current approaches for making porous materials, and the outcomes will enhance Australia's ability in frontier technologies and advanced materials.
Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and technique ....Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and techniques in the fields of reactive polymer synthesis, functional membrane fabrication and application in bioseparation. The innovative membranes developed in the project are able to improve the production capacity of therapeutic protein manufacturing processes, providing significant economic benefits to Australia.Read moreRead less
Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective mole ....Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective molecule transport. The membranes developed in the project have great potentials for improving the production capacity and sustainability of Australian industries, e.g., pharmaceutical manufacturing, bioethanol production and petroleum refining, providing significant economic and environmental benefits to Australia.Read moreRead less
Industrially Viable Routes for fabrication of Perovskite Solar Cells. Photovoltaic technology based on perovskite solar cell (PSC) is predicated to account for USD34.8 billion by 2027 in the global market. The current synthesis protocol using detrimental solvent for perovskite formation and the unsatisfactory stability of perovskite are two key barriers for commercial production of PSC. This project aims to develop new synthesis methods for stable perovskite materials in solar cells by utilizing ....Industrially Viable Routes for fabrication of Perovskite Solar Cells. Photovoltaic technology based on perovskite solar cell (PSC) is predicated to account for USD34.8 billion by 2027 in the global market. The current synthesis protocol using detrimental solvent for perovskite formation and the unsatisfactory stability of perovskite are two key barriers for commercial production of PSC. This project aims to develop new synthesis methods for stable perovskite materials in solar cells by utilizing green solvents that are viable for large scale production. The anticipated outcomes including industrially compatible material synthesis methods for efficient, stable PSC will significantly advance the manufacture capability and competitiveness of the industrial partner in this important area.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101190
Funder
Australian Research Council
Funding Amount
$359,446.00
Summary
Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collec ....Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collection. Expected project outcomes will place Australia at the forefront of practical low-cost and large-scale solar energy conversion technologies.Read moreRead less
Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine ....Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine. The resulting cell repositories could make a significant contribution to human health outcomes.Read moreRead less