Industrial Transformation Training Centres - Grant ID: IC140100022
Funder
Australian Research Council
Funding Amount
$2,148,935.00
Summary
ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused ....ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused on developing new capabilities and technologies that have the potential to facilitate, support, or catalyse the progressive deployment of portable separation science technologies into society. This will enable the development of new, portable and affordable analytical separation systems and contribute to creating a sustainable, globally competitive manufacturing industry in Australia.Read moreRead less
A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of ....A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of interest to capture the miRNA. Application of a magnetic field allows the levels of miRNA to be detected electrochemically. The expected outcome is a commercialisable biosensor for miRNA both as a diagnostic early detection device and a prognostic device for a range of miRNA biomarkers.Read moreRead less
Lab-on-a-chip mass spectrometry tools for testing illicit drugs. This project aims to develop fit-for-purpose mass spectrometry tools for roadside and workplace testing of illicit drugs. The technology will be based on nanostructured semiconductor chips that are surface-functionalised to enable molecular capture without extensive sample processing and subsequent detection by a novel combination of techniques. The technology is expected to be applicable to saliva, sweat and urine samples.
Porous silicon biosensor for rapid detection of water-borne contaminants. We have recently demonstrated the rapid degradation of porous silicon by certain transition metal complexes known as biomimetic catalysts. The catalysed degradation forms the basis of a new sensor principle where the porous layer serves as matrix, transducer and signal amplification stage. Using this mechanism, we will develop a biosensor for the rapid detection of contaminants (toxins etc.) in water resources. Reservoir w ....Porous silicon biosensor for rapid detection of water-borne contaminants. We have recently demonstrated the rapid degradation of porous silicon by certain transition metal complexes known as biomimetic catalysts. The catalysed degradation forms the basis of a new sensor principle where the porous layer serves as matrix, transducer and signal amplification stage. Using this mechanism, we will develop a biosensor for the rapid detection of contaminants (toxins etc.) in water resources. Reservoir water treatment today is reactive rather than preventive because current analysis is slow. Our biosensor can be turned into a field kit to improve water quality management and prevent acts of deliberate sabotage to the water supply.Read moreRead less
Forensic platform technologies for roadside and workplace testing based on nanostructured silicon chips. Roadside drug testing has recently been incorporated into government legislation throughout Australia and abroad. The objective of this project is to develop advanced analysis technologies for implementing effective roadside and workplace testing. The availability of these technologies will increase the safety of Australian drivers and workers.
Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high- ....Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high-quality water. Materials scientists, electrochemists, and specialists in water management and reuse aim to harness advances in nanostructured transducers and electrochemical protocols to develop online performance-monitoring technology. This project is expected to improve water treatment processes, removing viruses and reducing the risks and uncertainties of water recycling.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100056
Funder
Australian Research Council
Funding Amount
$3,975,864.00
Summary
ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning an ....ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning and artificial intelligence for the delivery of optimal solutions in diagnosis, treatment and wellbeing. The centre will deliver training in Industry 4.0 skills which will boost early-stage scale-up and accelerate the sector’s supply chain, which is pivotal for the Australian industries to maintain a competitive edge. Read moreRead less
Mass spectrometry to reveal the role of lipids in protein misfolding. This project aims to develop an integrated mass spectrometry-based approach to determine structures and dynamics of membrane associated proteins, and discover how lipids cause protein misfolding implicated in neurodegeneration. Lipid membranes may influence protein (mis)folding, aggregation and related toxicity. However, the complex and dynamic nature of the lipid-protein interactions involved means traditional methods cannot ....Mass spectrometry to reveal the role of lipids in protein misfolding. This project aims to develop an integrated mass spectrometry-based approach to determine structures and dynamics of membrane associated proteins, and discover how lipids cause protein misfolding implicated in neurodegeneration. Lipid membranes may influence protein (mis)folding, aggregation and related toxicity. However, the complex and dynamic nature of the lipid-protein interactions involved means traditional methods cannot easily characterise them, and they are poorly understood at a molecular level. The project expects to develop tools to bridge a critical gap in structural biology, while understanding lipid-protein interactions could lead to new therapies. This will ultimately provide benefits such as reduced health costs and better health outcomes.Read moreRead less