Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Two-dimensional nanoporous structured high performance gas evolution electrocatalysts. This project aims to develop nano-catalysts with high catalytic activity and rapid gas detachment properties for efficient fuel gas production. Heterogeneous electrocatalytic gas evolution reactions are important for clean energy generation and storage technologies, but high overpotentials caused by slow gaseous products’ detachment from catalyst surface severely hinder their efficiencies. Expected outcomes in ....Two-dimensional nanoporous structured high performance gas evolution electrocatalysts. This project aims to develop nano-catalysts with high catalytic activity and rapid gas detachment properties for efficient fuel gas production. Heterogeneous electrocatalytic gas evolution reactions are important for clean energy generation and storage technologies, but high overpotentials caused by slow gaseous products’ detachment from catalyst surface severely hinder their efficiencies. Expected outcomes include insights into gas bubble formation and evolution during electrocatalysis, effective catalyst structures to mitigate negative effects of gas bubble formation, and improved catalytic efficiency of gas evolution reactions and develop high performance electrocatalysts for fuel gas production.Read moreRead less
Bioactive Polymer Platelets. This project aims to develop polymers that can be self-assembled into 2D structures. Most nanoparticles developed for drug delivery are spherical. However these are not always the most efficacious as theory suggest that non-spherical nanoparticles have longer circulation times. It is proposed that discoid morphologies may be advantageous as they tend to migrate to the vascular membrane and adhere more efficiently. The polymers developed by this project will be tailor ....Bioactive Polymer Platelets. This project aims to develop polymers that can be self-assembled into 2D structures. Most nanoparticles developed for drug delivery are spherical. However these are not always the most efficacious as theory suggest that non-spherical nanoparticles have longer circulation times. It is proposed that discoid morphologies may be advantageous as they tend to migrate to the vascular membrane and adhere more efficiently. The polymers developed by this project will be tailored towards bioactive and biocompatible material to create a drug delivery platform for more efficient disease treatment. The outcome will be better understanding on how polymer platelets can be obtained and how they compare in their biological activity with spherical nanoparticles.Read moreRead less
Solar-driven thermochemical dissociation of carbon dioxide and water to produce carbon-neutral fuels. The biggest challenge to humanity of the century is to develop enabling clean energy resources to encounter rapidly diminished fossil fuel and accelerated global warming conditions. This project will offer a solution by developing a unique solar-driven thermochemical system capable of cleaving carbon dioxide and water to produce artificial syngas.
Tailoring physiologically-based nanomaterial fertilisers for the biofortification of zinc in broadacre crops. Soil zinc deficiency is a global issue causing low crop yield and malnutrition. This project will develop a new class of fertiliser formulations by combining advanced chemistry techniques with plant physiology knowledge and nanomaterial manufacturing. These products will be designed for enhanced agronomic efficiency and environmental safety.
Development of novel cathodes for next generation solid oxide fuel cells. This project will provide novel cathodes to reduce the operating temperature of the Solid Oxide Fuel Cell (SOFC) as low as 500 degrees celsius. The technology may lead to widespread utilization of SOFCs, thus providing great assistance to Australia's industries in term of reducing carbon dioxide emission and easing pressure from carbon tax.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100205
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A novel high-pressure system for multiple gas adsorption. This facility will equip researchers with analytical capabilities for research in the field of multi-gas adsorption. The facility will be of great significance to clean energy research, such as greenhouse gas emission control and hydrogen production and storage.
Discovery Early Career Researcher Award - Grant ID: DE180100736
Funder
Australian Research Council
Funding Amount
$362,446.00
Summary
High performing multifunctional silicon nanomaterials for bio-applications. This project aims to develop high-performance, multifunctional silicon nanomaterials, and to understand their physicochemical properties for bio-imaging. A range of high-quality multifunctional silicon-based bio-probes with novel fluorescent and magnetic properties will be developed for enhancing bio-imaging. The outcomes of the project will further strengthen Australia’s leading position in the targeted areas of Advance ....High performing multifunctional silicon nanomaterials for bio-applications. This project aims to develop high-performance, multifunctional silicon nanomaterials, and to understand their physicochemical properties for bio-imaging. A range of high-quality multifunctional silicon-based bio-probes with novel fluorescent and magnetic properties will be developed for enhancing bio-imaging. The outcomes of the project will further strengthen Australia’s leading position in the targeted areas of Advanced Materials and Nanotechnology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190101410
Funder
Australian Research Council
Funding Amount
$393,000.00
Summary
Structural and compositional controlled nanocarbon-based electrocatalyst. This project aims to develop highly effective carbon-based electro-catalysts for oxygen reduction by using elaborately designed metal-organic framework precursors. Oxygen reduction is a key cathodic reaction in clean energy technologies such as metal-air batteries and fuel cells. Expected outcomes of this project include carbon-based nanomaterials with optimised topological and compositional features. This project will bro ....Structural and compositional controlled nanocarbon-based electrocatalyst. This project aims to develop highly effective carbon-based electro-catalysts for oxygen reduction by using elaborately designed metal-organic framework precursors. Oxygen reduction is a key cathodic reaction in clean energy technologies such as metal-air batteries and fuel cells. Expected outcomes of this project include carbon-based nanomaterials with optimised topological and compositional features. This project will broaden the knowledge of designed synthesis of carbon-based nanocatalysts for oxygen reduction and provide a conceptual nanofabrication framework for preparing functional nanomaterials.Read moreRead less