Harnessing light and electricity to drive chemical synthesis. This project will explore and establish original strategies that use inputs of energy (light and electricity) to break or form chemical bonds, which can provide new or improved access to valuable compounds. In this way, this research will augment or enhance existing methods for the selective and direct manipulation of molecules by creating tools that allow chemists to prepare molecules under particularly mild conditions. The outcomes ....Harnessing light and electricity to drive chemical synthesis. This project will explore and establish original strategies that use inputs of energy (light and electricity) to break or form chemical bonds, which can provide new or improved access to valuable compounds. In this way, this research will augment or enhance existing methods for the selective and direct manipulation of molecules by creating tools that allow chemists to prepare molecules under particularly mild conditions. The outcomes of the project will include the development of new technology for organic synthesis and forging novel approaches for chemical alkylation and cross-coupling reactions. This can contribute to making important compounds more efficiently, safely and cheaper to produce in the future.Read moreRead less
High Oxidation State and Related Chemistry of Organic Compounds of Palladium. Palladium is able to form compounds containing palladium-carbon bonds, and compounds of this type occur in applications such as synthesis of organic compounds. The fundamental chemistry of this class of palladium compound is to be explored, in particular for the oxidation state +IV for palladium and with a focus on reactions that are relevant to processes occurring in organic synthesis applications. Particular emphas ....High Oxidation State and Related Chemistry of Organic Compounds of Palladium. Palladium is able to form compounds containing palladium-carbon bonds, and compounds of this type occur in applications such as synthesis of organic compounds. The fundamental chemistry of this class of palladium compound is to be explored, in particular for the oxidation state +IV for palladium and with a focus on reactions that are relevant to processes occurring in organic synthesis applications. Particular emphasis is placed on chemistry involving phosphorus compounds and unsaturated organic groups bonded to palladium, and on compounds containing groups that are able to join together to depart from palladium as organic compounds containing carbon-oxygen bonds.Read moreRead less
New Directions in Alkynylpalladium and Platinum Chemistry. Reactions involving palladium or platinum compounds with organic reagents are important for the synthesis of new materials and organic molecules, including pharmaceuticals. This research program will provide a better understanding of applications involving these metals, together with advances in fundamental chemistry of wide general interest at an international level, and high quality research training in an area essential for the conti ....New Directions in Alkynylpalladium and Platinum Chemistry. Reactions involving palladium or platinum compounds with organic reagents are important for the synthesis of new materials and organic molecules, including pharmaceuticals. This research program will provide a better understanding of applications involving these metals, together with advances in fundamental chemistry of wide general interest at an international level, and high quality research training in an area essential for the continued development of modern chemical and related industries in Australia.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Resolving dissolved organic matter: new multi-dimensional separation approaches. To fully understand and model global carbon cycles the source, nature and fate of oceanic dissolved organic carbon is an essential element. This project will develop, model and apply new orthogonol and complementary separation science based technologies to further the comprehensive characterisation and understanding of these complex systems.
Binuclear palladium motifs in synthetic transformations. Reactions involving palladium compounds with organic reagents are important for synthesis of new materials, pharmaceuticals, and molecules of value in medical research. This project will provide a better understanding of applications of palladium in these fields, and structural features of compounds containing chemical bonds linking metal atoms.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100129
Funder
Australian Research Council
Funding Amount
$249,000.00
Summary
Microflow ultra high pressure liquid chromatography - high resolution mass spectrometry for chemical exposure monitoring. Microflow ultra high pressure liquid chromatography – high resolution mass spectrometry for chemical exposure monitoring: Identifying new chemicals of interest in environmental or biological samples is the first critical step toward understanding their impact to human and environment. A state-of-the-art microflow ultra high performance liquid chromatography high resolution ma ....Microflow ultra high pressure liquid chromatography - high resolution mass spectrometry for chemical exposure monitoring. Microflow ultra high pressure liquid chromatography – high resolution mass spectrometry for chemical exposure monitoring: Identifying new chemicals of interest in environmental or biological samples is the first critical step toward understanding their impact to human and environment. A state-of-the-art microflow ultra high performance liquid chromatography high resolution mass spectrometer is fundamental to extend our research capabilities to new environmental contaminants and environmental exposure biomarkers, as well as consumption biomarkers of new illicit drugs and their metabolites. This instrument will fill an important gap in our capacity to link health/ecological risk to unknown chemicals and will allow interdisciplinary researchers to advance work in environmental toxicology, chemistry and forensics.Read moreRead less
Fluorinated surfactants and hydrocarbons at coastal airports. Fluorinated surfactants and hydrocarbons at coastal airports. This project aims to develop a model and parameters that describe transport and co-transport of fluoro-surfactants and hydrocarbons, priority pollutants with a wide range of physico-chemical properties, at coastal airports. Sixty percent of Australian airports are in the coastal plain, and all are affected by contamination from internationally banned fluoro-surfactants and ....Fluorinated surfactants and hydrocarbons at coastal airports. Fluorinated surfactants and hydrocarbons at coastal airports. This project aims to develop a model and parameters that describe transport and co-transport of fluoro-surfactants and hydrocarbons, priority pollutants with a wide range of physico-chemical properties, at coastal airports. Sixty percent of Australian airports are in the coastal plain, and all are affected by contamination from internationally banned fluoro-surfactants and hydrocarbons. Their extensive past use at firefighting training grounds resulted in costly remediation worldwide. Understanding the fate of persistent fluoro-surfactants from point sources, and their role in transporting non-polar chemicals such as hydrocarbons, will improve risk-based decision making. This research is expected to form the basis for effective risk management and intervention strategies.Read moreRead less
A new route to linear alpha olefins - catalytic isomerisation of internal olefins. Linear alpha olefins are an extremely important class of chemical building blocks used for everyday consumer products, such as plastics, detergents and lubricants. This research aims to develop a new platform technology for the production of these materials from low cost precursors.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100048
Funder
Australian Research Council
Funding Amount
$630,000.00
Summary
Atmospheric integrated research on burdens and oxidative capacity. Atmospheric integrated research on burdens and oxidative capacity: No single player in the Australian research community can make a large suite of atmospheric composition measurements, while the combined capability of the community is tremendous. Providing a platform to bring this capability together is cost effective and is expected to provide strong scientific return. This defines the requirements for Atmospheric Integrated Res ....Atmospheric integrated research on burdens and oxidative capacity. Atmospheric integrated research on burdens and oxidative capacity: No single player in the Australian research community can make a large suite of atmospheric composition measurements, while the combined capability of the community is tremendous. Providing a platform to bring this capability together is cost effective and is expected to provide strong scientific return. This defines the requirements for Atmospheric Integrated Research on Burdens and Oxidative capacity (AIR-BOX) to make a valuable contribution to Australian Atmospheric Science research. This project aims to provide a suite of mobile equipment including a chemical ionisation mass spectrometer, an ultraviolet-visible radiation spectrometer, a mini micropulse lidar, an in situ Fourier transform infrared spectrometer, and a cloud condensation nuclei counter. It will be capable of remote and autonomous deployment, real-time data transfer and control, a wide range of tracer measurements, flexible configuration, and physical as well as tracer measurements.Read moreRead less