New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordi ....New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordinary people to gain knowledge about the concentrations of molecular compounds in their environments and in themselves. This will stimulate economic and social benefits related to environmental testing and early disease diagnosis and generate new commercial opportunities for the Australian biotechnology industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100087
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-pro ....Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-property relationships, which are crucial for the development of the next generation of advanced materials with applications in electronics, optics, sensors, membranes, nanocoatings, biomaterials and polymer therapeutics. This facility underpins the efforts of the participating institutes in increasing the quality and quantity of research outcomes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100090
Funder
Australian Research Council
Funding Amount
$1,136,244.00
Summary
Xe-plasma dual beam for advanced future materials. This project aims to establish a state of the art Xe-Plasma dual-beam facility providing characterisation and fabrication capabilities to Australia’s research community. The project will use two beams - one Xe, the other electrons - to mill the surface of bulk materials which are subsequently analysed by electron or ion beam techniques to determine atomic-scale microstructure(s) and compositions. Anticipated outcomes are advanced materials engin ....Xe-plasma dual beam for advanced future materials. This project aims to establish a state of the art Xe-Plasma dual-beam facility providing characterisation and fabrication capabilities to Australia’s research community. The project will use two beams - one Xe, the other electrons - to mill the surface of bulk materials which are subsequently analysed by electron or ion beam techniques to determine atomic-scale microstructure(s) and compositions. Anticipated outcomes are advanced materials engineering and new knowledge about ancient and future materials. This is expected to provide significant advances across a variety of fields including material science, engineering and geology and enhance trans-disciplinary collaborations.Read moreRead less
Surface modification of semiconducting organic charge transfer complexes with metal nanoparticles to create a new class of multifunctional materials. This project aims to deliver a facile and cheap method to produce a class of nanostructured composite materials to be used in applications which will have environmental and social benefits such as photocatalyst development for water purification, biosensing and the creation of antibacterial fabrics to prevent the spread of infection.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100036
Funder
Australian Research Council
Funding Amount
$950,000.00
Summary
A customised triple-beam microscope for precise fabricating/characterising . This project aims to establish a customised triple-beam microscope to enable precise fabrication and polishing (using ion beams) and characterisation (using electron beam) of a wide range of advanced materials. It will provide solutions to prepare ultra-high quality and artefact-free specimens for transmission electron microscopy studies, and allow fabrication of unique nanostructures and nanostructured templates for hi ....A customised triple-beam microscope for precise fabricating/characterising . This project aims to establish a customised triple-beam microscope to enable precise fabrication and polishing (using ion beams) and characterisation (using electron beam) of a wide range of advanced materials. It will provide solutions to prepare ultra-high quality and artefact-free specimens for transmission electron microscopy studies, and allow fabrication of unique nanostructures and nanostructured templates for high-performance applications. The customised features of the proposed instrument are the first of its kind in Australia. The new knowledge developed through this project will significantly impact on scientific insights and practical applications of new materials related to physics, chemistry, biology, geology and engineering.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240101090
Funder
Australian Research Council
Funding Amount
$433,217.00
Summary
In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite ....In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite growth is affected by different surface modifications on the commercial graphite electrodes. The success of the project will lead to a fundamental understanding of the lithium dendrite formation mechanism, enabling the construction of significantly safer batteries.Read moreRead less
Microfluidics with core-shell beads: handling liquids like solids. Reducing waste of consumables in chemical reactions promises to solve environmental problems as well as enable novel applications in space. This project aims to establish a revolutionary fluid handling technology that lowers waste in the labs and in satellites. The project deciphers the fundamental physics behind our recent discovery of encapsulating a tiny liquid content in a solid shell, allowing for handling liquid samples lik ....Microfluidics with core-shell beads: handling liquids like solids. Reducing waste of consumables in chemical reactions promises to solve environmental problems as well as enable novel applications in space. This project aims to establish a revolutionary fluid handling technology that lowers waste in the labs and in satellites. The project deciphers the fundamental physics behind our recent discovery of encapsulating a tiny liquid content in a solid shell, allowing for handling liquid samples like solid particles. Examples of the benefit of this project are more precise detection of bacteria on earth and compact reactors in space. The research outcomes are instrumental for promoting a clean environment, good health, and creating new business opportunities, particularly in space industry, for Australians.Read moreRead less
The photons take charge: Elucidating the structure and stability of distonic radical anions by mass spectrometry and photoelectron spectroscopy. Recent work has discovered that certain radical anions have electronic configurations that defy chemical convention and exhibit exceptional radical stability. Exploitation of this breakthrough first requires experimental elucidation of the intrinsic electronic structure of these compounds and how it relates to their remarkable properties. This project w ....The photons take charge: Elucidating the structure and stability of distonic radical anions by mass spectrometry and photoelectron spectroscopy. Recent work has discovered that certain radical anions have electronic configurations that defy chemical convention and exhibit exceptional radical stability. Exploitation of this breakthrough first requires experimental elucidation of the intrinsic electronic structure of these compounds and how it relates to their remarkable properties. This project will probe the fundamental structure and energetics of radical anions by modifying instrumentation to enable multi-step gas-phase ion synthesis to be efficiently coupled with anion photoelectron spectroscopy. These investigations are essential to revealing the scope of this phenomenon in free radical chemistry and biology and could inform future development of new catalysts for polymerisation.Read moreRead less
Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chem ....Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chemistry. The expected outcomes of this project are faster measurement times and the possibility of imaging molecular weight distributions at a new level of detail. This project could place Australia at the cutting edge of size-exclusion chromatography phase design in partnership with a leading manufacturer of stationary phases.Read moreRead less
New laser and mass spectrometry-based tools for comprehensive structural elucidation of lipids and their biomolecular interactions. Lipid-related disorders such as obesity, diabetes and heart disease are reaching epidemic proportions. We propose the development of specialised instrumentation to identify and quantify lipids (fats) in tissue and culture samples thus providing Australian scientists with unique capabilities to investigate the mechanisms of disease.