How iron is cycled in Southern Ocean waters. This project aims to probe the Southern Ocean phytoplankton’s ability to take up and retain iron, using iron isotope tracer techniques. The Southern Ocean regulates Earth's climate, but the supply of iron to Southern Ocean surface waters is low, restricting the ability of phytoplankton to flourish and draw down carbon dioxide. The results are expected to reveal survival strategies of phytoplankton in this iron-poor environment and their potential abil ....How iron is cycled in Southern Ocean waters. This project aims to probe the Southern Ocean phytoplankton’s ability to take up and retain iron, using iron isotope tracer techniques. The Southern Ocean regulates Earth's climate, but the supply of iron to Southern Ocean surface waters is low, restricting the ability of phytoplankton to flourish and draw down carbon dioxide. The results are expected to reveal survival strategies of phytoplankton in this iron-poor environment and their potential ability to adapt to environmental change. This knowledge could be used to develop models to manage this climate-sensitive region.Read moreRead less
Pyrite: a deep-time capsule of ocean chemistry and atmosphere oxidation. Surprisingly little is known about trace element trends in past oceans, even though these data are vital for interpreting the evolution of the Earth's atmosphere, evolutionary pathways of marine life and cycles of major mineral deposits. Using laser-based analysis of sedimentary pyrite in deep marine rocks, this project aims to produce, for the first time, temporal variation curves for 25 trace elements in seawater over the ....Pyrite: a deep-time capsule of ocean chemistry and atmosphere oxidation. Surprisingly little is known about trace element trends in past oceans, even though these data are vital for interpreting the evolution of the Earth's atmosphere, evolutionary pathways of marine life and cycles of major mineral deposits. Using laser-based analysis of sedimentary pyrite in deep marine rocks, this project aims to produce, for the first time, temporal variation curves for 25 trace elements in seawater over the last 3.5 billion years. Preliminary research has validated the technique and demonstrated major changes in certain trace elements over geologically short periods. Outcomes will assist the minerals industry in the discovery of new deposits of zinc, copper, gold and iron ore in Australia.Read moreRead less
Metal complexes for sustainable light-driven synthesis. The aim of this project is to use cheap, abundant transition metal ions and visible light to enable challenging synthetic chemical reactions. The significant problems addressed are that most synthetic reactions using visible light currently require expensive precious metals, and fundamental reaction pathways used by Nature remain inaccessible. Both of these problems limit the scope of synthetic applications. The outcomes will be new knowled ....Metal complexes for sustainable light-driven synthesis. The aim of this project is to use cheap, abundant transition metal ions and visible light to enable challenging synthetic chemical reactions. The significant problems addressed are that most synthetic reactions using visible light currently require expensive precious metals, and fundamental reaction pathways used by Nature remain inaccessible. Both of these problems limit the scope of synthetic applications. The outcomes will be new knowledge and sustainable technologies that can better harness visible light for useful synthetic chemistry applications. The benefits will be more efficient and cost-effective routes to valuable molecules ubiquitous in everyday life.Read moreRead less
Coinage metal nanoclusters: synthesis, structure and reactivity. Metal catalysts play important roles in the multi-billion dollar production of many industrial and fine chemicals used in wide-ranging applications including pharmaceuticals, insecticides and polymers. Despite the importance of metal catalysed reactions, the molecular details of such processes remain poorly understood. Breakthrough studies highlight that reactions previously thought to be catalysed by discrete metal catalysts are i ....Coinage metal nanoclusters: synthesis, structure and reactivity. Metal catalysts play important roles in the multi-billion dollar production of many industrial and fine chemicals used in wide-ranging applications including pharmaceuticals, insecticides and polymers. Despite the importance of metal catalysed reactions, the molecular details of such processes remain poorly understood. Breakthrough studies highlight that reactions previously thought to be catalysed by discrete metal catalysts are in fact catalysed by metal nanoclusters. This project involves the application of advanced mass spectrometric and computational methods to explore the formation and reactivity of copper, silver and gold nanoclusters. Identification of key reactive intermediates will inform the design of next generation catalysts.Read moreRead less
On-fibre separation science with ambient ionisation mass spectrometry. This project aims to combine fibre-based electrofluidics and ambient ionisation mass spectrometry. Fibre-based electrophoresis is a separation technology which is cheaper, simpler and faster than pre-MS analyses. This project will use the fibre simultaneously as the ionisation platform for ambient mass spectrometry, combining the processes of separation and ionisation in a portable and flexible platform. The developed technol ....On-fibre separation science with ambient ionisation mass spectrometry. This project aims to combine fibre-based electrofluidics and ambient ionisation mass spectrometry. Fibre-based electrophoresis is a separation technology which is cheaper, simpler and faster than pre-MS analyses. This project will use the fibre simultaneously as the ionisation platform for ambient mass spectrometry, combining the processes of separation and ionisation in a portable and flexible platform. The developed technology is expected to provide new capability in bioanalysis, proteomics and rapid clinical diagnostics. Future benefits may include new commercial fibre based technologies which could be applied within industrial and clinical laboratories within the next ten years.Read moreRead less
A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of import ....A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of important organic reactions and enhancing collaboration nationally and internationally between computational and synthetic chemists. This should provide significant benefits in the form of improved chemical reactions for chemists to prepare new pharmaceuticals, agrochemicals and materials.Read moreRead less
Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability t ....Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability through the convergence of expertise and innovation in analytical chemistry, materials science and cellular biology, ultilising the latest technology and understanding of 3D micro/electrofluidics, to enable the study and stimulation of advanced biological models, sustained within precisely controlled 3D micro-environments.Read moreRead less
Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised .... Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised predictive models and a new understanding of the possible future evolutions of the ocean carbon cycle, acidification, and oxygenation. This should provide significant benefits such as predictions of future ocean health, identification of processes that are sensitive to change, and strategies for marine resource management.Read moreRead less
Understanding multi-scale dynamics of eddies in the East Australian Current. This project aims to provide the first rigorous quantification of the complex dynamics of rotating eddies (the weather systems of the ocean) and fronts on scales ranging from metres to 100s of kilometres and hours to weeks in the East Australian Current System. This project is at the frontier of oceanographic research and will provide significant new understanding of the physical and biogeochemical dynamics of eddies an ....Understanding multi-scale dynamics of eddies in the East Australian Current. This project aims to provide the first rigorous quantification of the complex dynamics of rotating eddies (the weather systems of the ocean) and fronts on scales ranging from metres to 100s of kilometres and hours to weeks in the East Australian Current System. This project is at the frontier of oceanographic research and will provide significant new understanding of the physical and biogeochemical dynamics of eddies and their interactions across multiple spatio-temporal scales, revealing their impacts on productivity along Australia’s most populous coastline. This will provide significant benefits such as improved ocean forecasting and sustainable management of Australian marine industries and seafood sector, supporting economic growth. Read moreRead less
Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimi ....Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimilate these metals is critical to the generation and aggressiveness of the toxins produced. These processes will be investigated in this study and conceptual and mathematical models will be developed which will assist in assessing management options for estuarine and coastal environments.Read moreRead less