Dynamics of the Southern Ocean. The Southern Ocean is critically important to future global climate: it controls the natural global carbon cycle and the distribution of heat and nutrients around the ocean. This project will investigate key uncertainties in the Southern Ocean's response to climate change, and thereby improve our capacity to predict future climate.
Distribution of ocean heat uptake and its implications for sea level and climate change. Increasing sea levels and ocean temperatures provide critical evidence of long term warming of the climate system. This project will investigate geographical changes in the vertical distribution of heat uptake by the ocean and contribution to sea level changes, including understanding of physical mechanisms and the role of human activity and other natural external and internal factors. The expected outcomes ....Distribution of ocean heat uptake and its implications for sea level and climate change. Increasing sea levels and ocean temperatures provide critical evidence of long term warming of the climate system. This project will investigate geographical changes in the vertical distribution of heat uptake by the ocean and contribution to sea level changes, including understanding of physical mechanisms and the role of human activity and other natural external and internal factors. The expected outcomes will contribute to place more rigorous constraints on the likelihood of future warming and sea level rise projections, and are aligned with scientific deliverables required to address key questions in support of Australia’s climate change policy.Read moreRead less
Southern Ocean oxygen variability since the last glacial maximum. Recently observed decreases in ocean oxygen concentration could decrease ocean biodiversity and accelerate climate change. This project will determine the links between climate change and ocean oxygenation since the last ice age, and provide a way to predict future oxygen concentrations.
Deep-sea carbonate cycles and their role in glacial-interglacial atmospheric CO2 changes. The causes for past atmospheric carbon dioxide (CO2) changes and their mechanistic links to the histories of climate and ocean carbonate chemistry remain elusive, but may hold future-relevant information. This project aims to use novel methods to quantify deep ocean carbonate ion concentrations, a critical but poorly constrained parameter of the global carbon cycle, at 10 key locations spanning the global o ....Deep-sea carbonate cycles and their role in glacial-interglacial atmospheric CO2 changes. The causes for past atmospheric carbon dioxide (CO2) changes and their mechanistic links to the histories of climate and ocean carbonate chemistry remain elusive, but may hold future-relevant information. This project aims to use novel methods to quantify deep ocean carbonate ion concentrations, a critical but poorly constrained parameter of the global carbon cycle, at 10 key locations spanning the global ocean during the last 350 000 years. By feeding new data into a model, this project aims to gain critical insights into mechanisms controlling past deep-sea carbonate cycles and atmospheric CO2 changes, thereby leading to improved understandings of the climate system.Read moreRead less
The stability and predictability of the Southern Hemisphere coupled ocean-atmosphere climate system. Our ability to adapt to and manage the effects of a changing climate is limited by our understanding of the ocean's response to changes in the atmospheric circulation. This project will establish the basis for the predictability of the climate system and provide state-of-the-art forecasts for climate adaptation.
Time to shine for constrained peptides as next-generation pharmaceuticals. Current methods for the screening and generation of peptide and protein drugs are laborious, expensive and often incompatible with the biological systems used in pharmaceutical industries. Leveraging recent advancements in chemistry and molecular biology, this project aims to improve the design, synthesis and screening of peptide-based pharmaceuticals. Key research outcomes are innovative biocompatible chemical transforma ....Time to shine for constrained peptides as next-generation pharmaceuticals. Current methods for the screening and generation of peptide and protein drugs are laborious, expensive and often incompatible with the biological systems used in pharmaceutical industries. Leveraging recent advancements in chemistry and molecular biology, this project aims to improve the design, synthesis and screening of peptide-based pharmaceuticals. Key research outcomes are innovative biocompatible chemical transformations for the screening of large peptide libraries, to unleash the revolutionary potential of constrained peptides in drug development. Expected benefits are reliable and cost-effective technologies for the rapid production of biologically active molecules for future targeted use in human and agricultural pharmaceuticals.Read moreRead less
The dynamics of convection - insights for ocean and climate physics and for solar thermal energy system design. This project will inform our understanding of, and response to, climate change by improving knowledge of ocean circulation and technology for renewable energy generation. The results will lead to better climate prediction models and understanding of ocean CO2 uptake, acidification and sea-level rise, and will help to reduce energy sector emissions.
Complementary pairs for next generation self-assembled systems . This project will employ a set of complementary pairings where separate sites fit together at metal ions in a specific fashion orthogonal to other pairings, like two jigsaw pieces, while forming a poor fit with other pairings. These pairings will allow retention and transfer of structural information. In this way, the bulk combination of relatively simple precursors will lead to self-assembled structures with well-defined seque ....Complementary pairs for next generation self-assembled systems . This project will employ a set of complementary pairings where separate sites fit together at metal ions in a specific fashion orthogonal to other pairings, like two jigsaw pieces, while forming a poor fit with other pairings. These pairings will allow retention and transfer of structural information. In this way, the bulk combination of relatively simple precursors will lead to self-assembled structures with well-defined sequence identity. This program will make and use complex abiotic molecules, enhancing outcomes in molecular information storage and transfer, molecular recognition and sensing, chemical transformations, and energy transport events, leading to economic and environmental benefits for Australia in industry and manufacturing.Read moreRead less
Engineered materials for future energy technologies. The development of new technologies to be applied in fuel generation, energy conversion and environmental remediation will have wide national and international impact. The cross-disciplinary and cross-institution research program proposed will draw on expertise within Australia and in Europe for the fabrication of materials for next generation energy devices. In the future, there is the potential that these materials could be fabricated within ....Engineered materials for future energy technologies. The development of new technologies to be applied in fuel generation, energy conversion and environmental remediation will have wide national and international impact. The cross-disciplinary and cross-institution research program proposed will draw on expertise within Australia and in Europe for the fabrication of materials for next generation energy devices. In the future, there is the potential that these materials could be fabricated within Australia and therefore lead to employment nationally, and income generated through the export of advanced catalysts, solar cells and sequestration materials.Read moreRead less
Bulk nanobubbles: from fundamentals to biomedical applications. This project aims to extend optical and acoustic tools to detect bulk nanobubbles, control their size-distributions, and understand how they interact with biomolecules. Liquids containing nanobubbles have numerous applications particularly in biomedicine. Using interdisciplinary approaches, this project expects to gain convincing evidence of the existence of bulk nanobubbles. This is expected to advance existing fundamental knowle ....Bulk nanobubbles: from fundamentals to biomedical applications. This project aims to extend optical and acoustic tools to detect bulk nanobubbles, control their size-distributions, and understand how they interact with biomolecules. Liquids containing nanobubbles have numerous applications particularly in biomedicine. Using interdisciplinary approaches, this project expects to gain convincing evidence of the existence of bulk nanobubbles. This is expected to advance existing fundamental knowledge at the forefront of soft matter research, and give Australia a decisive technological head start in a competitive and lucrative industry through patentable technology.Read moreRead less