Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Ex ....Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Expected outcomes and benefits include new fundamental understanding of the effect of particle mechanical properties on cell function, new insights into T cell activation and expansion, and new classes of stiffness-tunable fit-for-purpose materials for various applications in cell manufacturing.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL140100081
Funder
Australian Research Council
Funding Amount
$2,380,000.00
Summary
Engineering hybrid photocatalytic systems for sustainable fuel generation. Engineering hybrid photocatalytic systems for sustainable fuel generation. The project aims to develop next generation hybrid photo-(co)catalyst and gaseous photoelectrode systems that will effectively harness solar energy to transform carbon dioxide into sustainable fuels using a multi-scale approach: designing hetero-structured material systems; elucidating surface reaction mechanisms, and engineering coupled photo/ther ....Engineering hybrid photocatalytic systems for sustainable fuel generation. Engineering hybrid photocatalytic systems for sustainable fuel generation. The project aims to develop next generation hybrid photo-(co)catalyst and gaseous photoelectrode systems that will effectively harness solar energy to transform carbon dioxide into sustainable fuels using a multi-scale approach: designing hetero-structured material systems; elucidating surface reaction mechanisms, and engineering coupled photo/thermal-catalytic and unique gaseous photoelectrochemical systems. This project aims to yield fundamental new knowledge for the economical conversion and storage of solar energy as an environmentally benign chemical fuel, as well as create contemporary material systems and reactors for photo- and thermal-catalysis and photoelectrochemical reactions that utilise carbon dioxide as a feedstock.Read moreRead less
Interfacial design for high performance carbon fibre polymer composites. This project aims to develop customisable surfaces on carbon fibres to complement any intended resin for composite materials. Poor fibre-to-matrix adhesion is currently a known weakness of carbon fibre composites, hindering the large scale translation of these materials into mass transport solutions The outcomes of this project will be the development of superior composites and the fundamental knowledge of what interfacial ....Interfacial design for high performance carbon fibre polymer composites. This project aims to develop customisable surfaces on carbon fibres to complement any intended resin for composite materials. Poor fibre-to-matrix adhesion is currently a known weakness of carbon fibre composites, hindering the large scale translation of these materials into mass transport solutions The outcomes of this project will be the development of superior composites and the fundamental knowledge of what interfacial molecular interactions are required to obtain composites able to tolerate high shear forces.Read moreRead less
A design-led approach for multifunctional composites . This project aims to remove some of the limitations of carbon fibre composites by introducing novel functionality into the underlying carbon fibre. The project expects to modify carbon fibres, predict their functionality and develop new high-performance resins. The expected outcomes include enabling carbon composite materials to have high strength-to-weight ratio, durability, toughness, minimal maintenance, without compromising processabilit ....A design-led approach for multifunctional composites . This project aims to remove some of the limitations of carbon fibre composites by introducing novel functionality into the underlying carbon fibre. The project expects to modify carbon fibres, predict their functionality and develop new high-performance resins. The expected outcomes include enabling carbon composite materials to have high strength-to-weight ratio, durability, toughness, minimal maintenance, without compromising processability and the ability to manufacture at high volumes. The benefits should include a significant boost to Australia’s ability to lead economically important manufacturing innovations across a range of sectors including defence, energy and construction. Read moreRead less
Develop Catalyst Materials for Future Fuels by Operando Computation. This project aims to design catalyst materials for the production of future fuels (green ammonia, hydrocarbon and alcohol). Using carbon and nitrogen as energy carriers, these fuels are generated from renewable sources such as wind or solar; they are safe, reliable, and possess high energy density. The outcomes include advance in computational electrochemistry to the Opeando level, electrocatalysts design principles with clearl ....Develop Catalyst Materials for Future Fuels by Operando Computation. This project aims to design catalyst materials for the production of future fuels (green ammonia, hydrocarbon and alcohol). Using carbon and nitrogen as energy carriers, these fuels are generated from renewable sources such as wind or solar; they are safe, reliable, and possess high energy density. The outcomes include advance in computational electrochemistry to the Opeando level, electrocatalysts design principles with clearly articulated reaction mechanisms, and candidate materials for experimental validation. Facilitated by advanced computation techniques and reliable catalyst materials design procedure, this project will address the biggest challenge in future fuel generation, which is the lack of efficient catalyst materials. Read moreRead less
Helium recovery from liquefied natural gas waste stream using nanoporous mxene materials. The waste streams from many liquefied natural gas (LNG) industries still contains valuable helium, a possible next mineral to sustain our economic growth. This project aims to efficiently separate helium from methane and nitrogen via the layered two dimensional materials. This project will seek to understand the assembling behaviour of these nano-sized Mxene flakes and their molecular sieving properties. Au ....Helium recovery from liquefied natural gas waste stream using nanoporous mxene materials. The waste streams from many liquefied natural gas (LNG) industries still contains valuable helium, a possible next mineral to sustain our economic growth. This project aims to efficiently separate helium from methane and nitrogen via the layered two dimensional materials. This project will seek to understand the assembling behaviour of these nano-sized Mxene flakes and their molecular sieving properties. Australia is playing a leading role in the global liquefied natural gas (LNG) production and trade. This project expects to further position Australia at the forefront of intellectual leadership in the field of gas processing and material development. This will have significant benefits, such as further improving these LNG projects economics by cost-effectively producing helium as a valuable by-product via advanced porous nano-materials.Read moreRead less
Design Of Practical Passive Cooling Radiators Utilising Spectrally Selective Covers And Surfaces. Radiative cooling offers a means to cool buildings sustainably without complex and costly heat pumps or air conditioners. Units similar to solar panels can be designed with surfaces which radiate mostly into the 8 - 12 micron atmospheric window, which has a radiance much less than for other wavelengths. Commercial development has been limited by problems associated with the degradation, performance ....Design Of Practical Passive Cooling Radiators Utilising Spectrally Selective Covers And Surfaces. Radiative cooling offers a means to cool buildings sustainably without complex and costly heat pumps or air conditioners. Units similar to solar panels can be designed with surfaces which radiate mostly into the 8 - 12 micron atmospheric window, which has a radiance much less than for other wavelengths. Commercial development has been limited by problems associated with the degradation, performance or cost of radiator surfaces. This project seeks to improve both performance and durability with innovative use of alternative materials and sputtered coatings suitable for mass manufacture, and to test the outdoor performance of laboratory produced radiative plates.Read moreRead less
New bar-encoded polymer microbeads for multiplexed bioanalysis-a quick and high-throughput approach for complex disease diagnosis. Distinguishable new bar-encoded (element-encoded) polymer microbeads associated with a mass spectroscopy-flow cytometer detector provide a novel platform for highly multiplexed biological analysis. Such an approach can simultaneously identify many non-self-agents at low concentrations, which facilitates early-stage complex disease diagnosis.
A new paradigm in near-net-shape advanced ceramic component processing. The raw materials for high performance ceramics (such as alumina and zirconia) are readily available and produced in Australia. Nearly all of these raw materials are exported. The development of processing to make high value added ceramic components from these raw materials will result in greater profit and more jobs for Australians. The proposed research is to develop a novel innovative process to drive a value adding ce ....A new paradigm in near-net-shape advanced ceramic component processing. The raw materials for high performance ceramics (such as alumina and zirconia) are readily available and produced in Australia. Nearly all of these raw materials are exported. The development of processing to make high value added ceramic components from these raw materials will result in greater profit and more jobs for Australians. The proposed research is to develop a novel innovative process to drive a value adding ceramic processing industry in Australia.Read moreRead less
Short- and long-term corrosion of steels in highly calcareous seawaters . This project aims to quantify the development of the long-term (25-100 year) protective effect of calcareous deposits on the marine corrosion of mild steels. This is significant because such steels used extensively in major and very expensive coastal and offshore infrastructure. The project outcomes will improve scientific understanding, including the role of microbiological activity. It will develop and calibrate corrosio ....Short- and long-term corrosion of steels in highly calcareous seawaters . This project aims to quantify the development of the long-term (25-100 year) protective effect of calcareous deposits on the marine corrosion of mild steels. This is significant because such steels used extensively in major and very expensive coastal and offshore infrastructure. The project outcomes will improve scientific understanding, including the role of microbiological activity. It will develop and calibrate corrosion prediction models using classical and recently available 100 year data from Europe, the Pacific, Australia and also new project-specific experimental data. These models are expected to be of benefit for Australian engineering consultants in maintain their internationally competitive edge in offshore engineering.Read moreRead less