Discovery Early Career Researcher Award - Grant ID: DE240100722
Funder
Australian Research Council
Funding Amount
$362,245.00
Summary
Enabling Novel Hydrogen Storage via Combustible Ice for a Low-Carbon Future. This project aims to develop a new method for sustainable hydrogen storage. Hydrogen is vital for decarbonising Australia's economy, yet finding an efficient way for hydrogen storage is a global challenge. This project seeks to encapsulate hydrogen effectively in water to produce hydrogen-carrying combustible ice for efficient large-scale hydrogen storage, taking the advantages of water as the safest and cheapest raw ma ....Enabling Novel Hydrogen Storage via Combustible Ice for a Low-Carbon Future. This project aims to develop a new method for sustainable hydrogen storage. Hydrogen is vital for decarbonising Australia's economy, yet finding an efficient way for hydrogen storage is a global challenge. This project seeks to encapsulate hydrogen effectively in water to produce hydrogen-carrying combustible ice for efficient large-scale hydrogen storage, taking the advantages of water as the safest and cheapest raw material. Expected outcomes are cutting-edge knowledge and a new pathway of hydrogen storage. This project would contribute to turning Australia’s abundant renewable energy resources into substantial economic and environmental benefits and promote Australia's competitive edge in the global transition toward a low-carbon future.Read moreRead less
Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less
Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. S ....Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. Significant outcomes are expected to be achieved through building fundamental understanding around this breakthrough, including new concepts for hierarchical nanomaterials based on biomolecular design, new molecular and engineering design rules for core-shell materials, and novel materials for applications in sustained release and delivery systems.Read moreRead less
Multi-scale Process Modelling for Intelligent Control. Processing and manufacturing systems are inherently multi-scale in their behaviour. From the molecular scale to the enterprise-wide scale. This and other attributes of the individual models create difficulties in the design and control of such systems. This project will develop suitable multi-scale measures (metrics) for process models based on an object oriented assumption based modelling language. It will lead to enhanced intelligent contr ....Multi-scale Process Modelling for Intelligent Control. Processing and manufacturing systems are inherently multi-scale in their behaviour. From the molecular scale to the enterprise-wide scale. This and other attributes of the individual models create difficulties in the design and control of such systems. This project will develop suitable multi-scale measures (metrics) for process models based on an object oriented assumption based modelling language. It will lead to enhanced intelligent control strategies and improved operational performance through use of the most appropriate model. The work will focus on industrially important reaction and particulate processing systemsRead moreRead less
Improving biological nitrogen removal by enhanced mixing in non-aerated bioreactors. Mixing has been identified as a key factor in achieving enhanced performance out of existing and upgraded bioreactors. There is currently a poor understanding of the relationship between non-ideal flow and performance in wastewater treatment bioreactors. The project will determine this relationship and subsequently use it to show how reactor performance can be improved, providing first criteria by which mixing c ....Improving biological nitrogen removal by enhanced mixing in non-aerated bioreactors. Mixing has been identified as a key factor in achieving enhanced performance out of existing and upgraded bioreactors. There is currently a poor understanding of the relationship between non-ideal flow and performance in wastewater treatment bioreactors. The project will determine this relationship and subsequently use it to show how reactor performance can be improved, providing first criteria by which mixing can be assessed, and second a systematic methodology for improving reactor performance by improving mixing.Read moreRead less
Discrete Element Method for Analysis and Design of Pharmaceutical Encapsulation. Tablets represent the preferred method of dose delivery in the pharmaceutical industry, with over 80% of the market. PressFit - gelcaps have recently been developed, which encase a tablet core within a gelatin coating. The product combines the consumer appeal of capsules with the processing convenience of tablets, and provides a high degree of tamper-resistance. An important issue is that the caplets are required ....Discrete Element Method for Analysis and Design of Pharmaceutical Encapsulation. Tablets represent the preferred method of dose delivery in the pharmaceutical industry, with over 80% of the market. PressFit - gelcaps have recently been developed, which encase a tablet core within a gelatin coating. The product combines the consumer appeal of capsules with the processing convenience of tablets, and provides a high degree of tamper-resistance. An important issue is that the caplets are required to have very precise dimensional precision, an issue not previously of high priority for tabletting . This project seeks to enhance the competitive advantage of this new technology, through a combination of advanced mathematical modeling supported by experiments.Read moreRead less
Plasma-Catalytist Hybrid Process for Simultaneous Removal of NOx and SOx. Coal combustion provides over 80% of the electricity produced in Australia, with the power stations being major emitters of the pollutants NOx and SOx. This project will potentially lead to a new technology to simultaneously remove NOx and SOx in a single and economical process, eliminating the secondary waste streams that disadvantage current competing technologies. This will provide: significant environmental benefits f ....Plasma-Catalytist Hybrid Process for Simultaneous Removal of NOx and SOx. Coal combustion provides over 80% of the electricity produced in Australia, with the power stations being major emitters of the pollutants NOx and SOx. This project will potentially lead to a new technology to simultaneously remove NOx and SOx in a single and economical process, eliminating the secondary waste streams that disadvantage current competing technologies. This will provide: significant environmental benefits for Australia in reducing these dangerous atmospheric pollutants; economic advantage to our power stations by enabling cheaper, more efficient technologies and consolidate Australia's leading position in the world in air pollution control. Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this ....Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this project include a new fundamental understanding of the effect of mechanical properties on cell function, novel insights into the regulation of stem cell fate, and the development of a new class of roughness-tunable materials suitable for use in tissue engineering and pharmaceutical applications. Read moreRead less