Engineering a nanovaccine for cost-effective influenza poultry vaccination. The project aims to develop a new single-dose, room temperature-stable nanovaccine for cost-effective influenza poultry vaccination. The nanovaccine is based on viral protein assembly modularised to present multiple copies of influenza antigen. Particularly, this project focuses on the engineering of this vaccine manufacturing and formulation for a room temperature-stable vaccine. The resulting engineered vaccine would p ....Engineering a nanovaccine for cost-effective influenza poultry vaccination. The project aims to develop a new single-dose, room temperature-stable nanovaccine for cost-effective influenza poultry vaccination. The nanovaccine is based on viral protein assembly modularised to present multiple copies of influenza antigen. Particularly, this project focuses on the engineering of this vaccine manufacturing and formulation for a room temperature-stable vaccine. The resulting engineered vaccine would play an important role in preventing avian influenza outbreaks, which are currently affecting both developed and developing countries, costing millions of dollars due to the death and culling of infected poultry.Read moreRead less
Seismic analysis of cracking and deformations in concrete gravity dams. This project aims to establish a rational predictive capability for the responses of concrete gravity dams subject to extreme design earthquakes. This will include the development of innovative numerical methods for effective modelling of crack propagation and closure, large slips on crack faces and weak interfaces, dam-reservoir interaction, dam-foundation interaction and automatic mesh generation. The expected outcomes of ....Seismic analysis of cracking and deformations in concrete gravity dams. This project aims to establish a rational predictive capability for the responses of concrete gravity dams subject to extreme design earthquakes. This will include the development of innovative numerical methods for effective modelling of crack propagation and closure, large slips on crack faces and weak interfaces, dam-reservoir interaction, dam-foundation interaction and automatic mesh generation. The expected outcomes of the project will be a significantly improved prediction tool. It is also anticipated that the project will result in improvements in dam and public safety, and more efficient use of funds for dam safety upgrades and management.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100015
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation ....ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation of infrastructure design in Australia and internationally. Achieving carbon neutral infrastructure in its whole life will bring significant far-reaching benefits, including equipping industry with tools required to meet Australia’s emission reduction targets as well as economic, commercial, environmental, and social gains.Read moreRead less
Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by ....Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by modifying the levels of road and rail crossings and providing guard rails in the recesses of these modified level crossings. The theories are intended be developed using nonlinear dynamic computational methods and laboratory experiments. The outcomes are expected to enable reduction in the severity of level crossing accidents and hence save lives and costs of derailment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100133
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
National Facility for Physical Blast Simulation (NFPBS). Recent terrorist attacks employing large quantities of high explosives have prompted the international demand for experimental investigation of civil infrastructure response to shock wave loadings. The National Facility for Physical Blast Simulation (NFPBS) is one of only a few in the world that are suitable for conducting experimental research via a physically generated blast approach.
Erosion of embankment dams and dam spillways. In excess of $250M is spent annually to maintain, upgrade, improve safety and monitor performance of Australian dams. Improved methods for assessing both spillway and internal erosion, the cause of 50 per cent of embankment dam failures and incidents requiring repairs, will be developed, maximising dam safety and minimising maintenance expenditure.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100185
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
High throughput microbial microculture and single cell analysis facility. High throughput microbial microculture and single cell analysis facility:
To support the emerging research area of microbial heterogeneity and variation in response to conditions, this project aims to establish a facility centred on a 24-microbioreactor system for high throughput microbial culturing. This is designed to be connected to two complementary analysis techniques – flow cytometry and high resolution infra-red mi ....High throughput microbial microculture and single cell analysis facility. High throughput microbial microculture and single cell analysis facility:
To support the emerging research area of microbial heterogeneity and variation in response to conditions, this project aims to establish a facility centred on a 24-microbioreactor system for high throughput microbial culturing. This is designed to be connected to two complementary analysis techniques – flow cytometry and high resolution infra-red microscopy – for the non-destructive measurement of metabolic activities and mapping of constituents of whole cells. This would help us to determine the variation in response between organisms, to guide cell line development and process optimisation for a wide range of biotechnology applications. Expected outcomes may apply to Australia’s brewing, wine, food processing, aquaculture, biofuels, biomedical and biotechnology industries.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100006
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Nanoscience-based Construction Material Manufacturing. ARC Research Hub for Nanoscience-based Construction Material Manufacturing. This research hub aims to develop novel construction materials including binders, cement additives, high-performance concrete materials, concrete structural systems, polymer composites, and pavement materials. The multi-disciplinary hub provides a centralised platform to transform the construction materials industry into an advanced manufacturing ....ARC Research Hub for Nanoscience-based Construction Material Manufacturing. ARC Research Hub for Nanoscience-based Construction Material Manufacturing. This research hub aims to develop novel construction materials including binders, cement additives, high-performance concrete materials, concrete structural systems, polymer composites, and pavement materials. The multi-disciplinary hub provides a centralised platform to transform the construction materials industry into an advanced manufacturing sector delivering sustainable and resilient infrastructure assets. The hub intends to develop nanotechnology, cement chemistry, concrete technology and extreme engineering solutions; and to train the next generation of skilled workers, re-positioning Australian industry competitiveness and global market leadership to capture international infrastructure development opportunities.Read moreRead less
Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be disc ....Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be discovered and then incorporated into new microwave components and/or devices developed in response to the requirements of the international wireless telecommunications market. The requested PhD student will gain experience in both the industrial and academic worlds and the skills needed to be part of Australia's high-tech workforce. Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC180100021
Funder
Australian Research Council
Funding Amount
$4,163,359.00
Summary
ARC Training Centre for the Development of Tools for Fragment Based Design. The ARC Training Centre for the Development of Tools for Fragment Based Design aims to inspire the next generation of drug discovery research leaders. It plans to provide direct experience with industry partners, training and master classes in early stage drug-discovery from industry experts. The Centre is expected to accelerate research translation and industry engagement by providing an efficient strategy for the scree ....ARC Training Centre for the Development of Tools for Fragment Based Design. The ARC Training Centre for the Development of Tools for Fragment Based Design aims to inspire the next generation of drug discovery research leaders. It plans to provide direct experience with industry partners, training and master classes in early stage drug-discovery from industry experts. The Centre is expected to accelerate research translation and industry engagement by providing an efficient strategy for the screening of a biological target and early medicinal chemistry for optimisation. The expected outcome of the Centre is to equip the trainees with the skills to make key contributions to the sustainability and growth of the sector and to provide significant capacity to address global challenges for 21st century pharmaceutical innovation.Read moreRead less