Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100121
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
A facility for the nanoscale imaging and characterisation of materials. Nanotechnology is dependent on measuring surface properties and this cutting-edge scanning probe microscopy facility will provide this capability. Atomic resolution imaging, along with spectroscopy for chemical information, and nanoindentation for physical information, will generate solutions for physical and life sciences, and materials engineering.
Developing a multicomponent platform for targeted gene delivery. Gene delivery systems are important tools in biological research and offer many exciting future prospects. Delivering gene material is very difficult in practice: rapid deterioration, poor cell uptake, and reaching the right tissue and cell types are major obstacles. Ways to overcome each barrier individually have been suggested in existing research but these components have not yet been combined in a single solution, which this pr ....Developing a multicomponent platform for targeted gene delivery. Gene delivery systems are important tools in biological research and offer many exciting future prospects. Delivering gene material is very difficult in practice: rapid deterioration, poor cell uptake, and reaching the right tissue and cell types are major obstacles. Ways to overcome each barrier individually have been suggested in existing research but these components have not yet been combined in a single solution, which this project will tackle. This proposal aims to create a technology to stabilise and deliver active gene material to target cells. The gene delivery tool developed in this project will advance biological research greatly with many potential future applications.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120101788
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Shape sorting of nanoparticles at oil-water interfaces in microchannels. This project aims to study the effect of shape on the adsorption of nanoparticles at an oil/water interface and develop a rapid, inexpensive, efficient, versatile method for shape sorting of nanoparticles using a microfluidic approach. This technique can be applied for fractionation of synthetic nanoparticles, biosample analysis and environmental monitoring.
Development of a multicomponent delivery system for oligonucleotides. Gene therapy has the ability to prevent faulty genes from causing disease, however the ability to deliver genetic material into specific cells remains a major barrier. Our research will overcome this hurdle by generating systems that are superior to existing technologies.
Cause and effect: new mechanisms of particles formation in thunderstorms. This project aims to identify meaningful and specific indicators for predicting particle formation and alteration during thunderstorms. How thunderstorms develop is well-understood. However, identifying meaningful and specific indicators for predicting particle alteration during a thunderstorm is still not clear. This project will practically contribute to the evidence of the impact of air particulates, thereby having dire ....Cause and effect: new mechanisms of particles formation in thunderstorms. This project aims to identify meaningful and specific indicators for predicting particle formation and alteration during thunderstorms. How thunderstorms develop is well-understood. However, identifying meaningful and specific indicators for predicting particle alteration during a thunderstorm is still not clear. This project will practically contribute to the evidence of the impact of air particulates, thereby having direct implications for meteorological, and air pollution policy in Australia and worldwide. This project will allow researchers to understand the impact of these factors on the escalation of the causative effects, and to find a way to prevent unnecessary fatal outcomes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101101
Funder
Australian Research Council
Funding Amount
$348,741.00
Summary
Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronic ....Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronics from its current status as a fundamental tool to real-world applications. Key approaches will be the use of surface chemistry to develop new methods of wiring single molecules and the integration of robust single-molecule junctions with semiconducting electrodes. The expected project outcomes pave the way for single-molecule electronic and analytical devices.Read moreRead less
On-water electrochemistry: redox catalysis at the water surface. From plastics to pharamaceuticals, chemists rely extensively on expensive and environmentally damaging solvents and reactants. In water, greener and cheaper electricity-driven reactions currently suffer from low velocity and poor selectivity. The project aims to develop the science of on-water electrochemistry, to make electricity-driven organic reactions in water viable. Demonstrating that for electrochemical reactions, rates and ....On-water electrochemistry: redox catalysis at the water surface. From plastics to pharamaceuticals, chemists rely extensively on expensive and environmentally damaging solvents and reactants. In water, greener and cheaper electricity-driven reactions currently suffer from low velocity and poor selectivity. The project aims to develop the science of on-water electrochemistry, to make electricity-driven organic reactions in water viable. Demonstrating that for electrochemical reactions, rates and selectivities increase on water’s surface rather than in its bulk will remove fundamental constraints on the viability of aqueous electro-synthesis – moving beyond current reactor designs to transform our view of electrochemistry and improve the sustainability of the chemical industry.Read moreRead less
Sliding diodes: harvesting triboelectricity with surface chemistry. This project aims to create new methods for the conversion of friction at vibrating metal–semiconductor contacts into a continuous source of electricity; an autonomous technology to power miniature electronics in applications spanning health management to environmental sensing. The expected outcomes of this project include the development of new surface chemistry and miniature semiconductor technologies, with benefits for the de ....Sliding diodes: harvesting triboelectricity with surface chemistry. This project aims to create new methods for the conversion of friction at vibrating metal–semiconductor contacts into a continuous source of electricity; an autonomous technology to power miniature electronics in applications spanning health management to environmental sensing. The expected outcomes of this project include the development of new surface chemistry and miniature semiconductor technologies, with benefits for the design and function of silicon-based devices such as life-critical pacemakers, and self-powered monitors in remote/dangerous places.Read moreRead less
The control of chromosome division during female meiosis. Mammalian eggs are stored life-long and finally mature in the hours before ovulation. This project examines how the chromosomes in the egg are separated properly so as to produce a mature egg capable of being fertilized by a sperm. Often in eggs chromosome division is imprecisely executed, and this project will help us understand why this occurs.
Discovery Early Career Researcher Award - Grant ID: DE160100589
Funder
Australian Research Council
Funding Amount
$402,711.00
Summary
Cadmium-free one-dimensional colloidal nanocrystal heterostructures. The goal of this project is to develop innovative colloidal nanocrystal heterostructures to provide the basis for eco-friendly optoelectronic devices and photocatalysis as well as other advanced applications. One-dimensional semiconductor nanocrystals have desirable electronic and catalytic properties (a linearly polarised emission, large absorption cross section, reduced lasing threshold and improved charge separation and tran ....Cadmium-free one-dimensional colloidal nanocrystal heterostructures. The goal of this project is to develop innovative colloidal nanocrystal heterostructures to provide the basis for eco-friendly optoelectronic devices and photocatalysis as well as other advanced applications. One-dimensional semiconductor nanocrystals have desirable electronic and catalytic properties (a linearly polarised emission, large absorption cross section, reduced lasing threshold and improved charge separation and transport). However, present investigations of these materials are mainly limited to highly toxic cadmium chalcogenides. This project aims to explore a family of cadmium-free colloidal nanocrystal heterostructures with the desired properties. The project intends to investigate their growth mechanisms, properties and effects to support product development and advance the fundamental knowledge of electronics at the nanoscale.Read moreRead less