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The development of tuneable materials to allow the three-dimensional printing of cells. New low cost three-dimensional (3D) printers and reagents will be developed during this project to allow cancer biologists to print cells and polymers as more realistic 3D tissue models for biological assays. Such technology will be important for performing basic research into cancers as well as for providing better tools for drug testing.
Single-molecule view of actin-tropomyosin filament dynamics. This project aims to develop a microscopy platform to resolve how filaments of the cytoskeleton, the cell's internal scaffolding, are assembled. This technology will then be used to understand how drugs can target specific components and functions of the cytoskeleton that are hijacked in cancer cells.
Special Research Initiatives - Grant ID: SR180100030
Funder
Australian Research Council
Funding Amount
$1,103,883.00
Summary
Development of electrochemically activated sorbents for PFAS defluorination. This project aims to develop a new treatment technology to completely defluorinate per- and poly-fluroalkyl substances (PFAS) and to treat significant water quantities. The majority of existing water treatment technologies are unable to remove PFAS to the desired extent, are prohibitively expensive or are only useful for a very limited lifespan. This project is expected to develop a new treatment technology with the abi ....Development of electrochemically activated sorbents for PFAS defluorination. This project aims to develop a new treatment technology to completely defluorinate per- and poly-fluroalkyl substances (PFAS) and to treat significant water quantities. The majority of existing water treatment technologies are unable to remove PFAS to the desired extent, are prohibitively expensive or are only useful for a very limited lifespan. This project is expected to develop a new treatment technology with the ability to completely defluorinate PFAS, treat significant water quantities and help address many of the pressing concerns facing water treatment operators. This technology is also scalable, and can potentially be used to treat significant quantities of contaminated water.Read moreRead less
Carbon-based electrode materials for electrochemical energy storage and water desalination. Clean energy and water resource are two critical issues for an environmentally sustainable Australia. The research project will lead to the discovery of innovative carbon-based electrode materials with well-designed physical and chemical properties for clean energy storage and alternative water desalination technology.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100121
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
A facility for the nanoscale imaging and characterisation of materials. Nanotechnology is dependent on measuring surface properties and this cutting-edge scanning probe microscopy facility will provide this capability. Atomic resolution imaging, along with spectroscopy for chemical information, and nanoindentation for physical information, will generate solutions for physical and life sciences, and materials engineering.
Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide f ....Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide further employment for Australians, building on Universal Biosensor’s proven record of commercialization in Australia. The project will lead to training of Australian researchers in nanotechnology and in utilization of key Australian science infrastructure including the Australian Synchrotron and the Melbourne Centre for Nanofabrication.Read moreRead less
Wet Particulate Materials - Flow or Fracture? Most advanced materials are produced from starting materials in the form of fine particles. Powders, especially in ceramic engineering, are first processed wet into near-final shape. Improved understanding of the fracture of particle networks is critical in order to process nano-sized advanced ceramic materials for use in solar energy harvesting and extreme heat engine applications as well as minimising drying cracks in paints and coatings. The resea ....Wet Particulate Materials - Flow or Fracture? Most advanced materials are produced from starting materials in the form of fine particles. Powders, especially in ceramic engineering, are first processed wet into near-final shape. Improved understanding of the fracture of particle networks is critical in order to process nano-sized advanced ceramic materials for use in solar energy harvesting and extreme heat engine applications as well as minimising drying cracks in paints and coatings. The research aims to identify the fundamental link between particle network strength and structure and the fracture of wet powder bodies. The microscopic mechanisms that control the behaviour will be investigated with a particular focus on toughening mechanisms including the influence of plasticity.Read moreRead less
Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design ....Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design of systems that function much more closely to human milk will enable the development of new products with flow on benefits in human nutrition and increased utilisation of products from our dairy industry.Read moreRead less