Deciphering Signalling Pathways Regulating Iron Homeostasis
Funder
National Health and Medical Research Council
Funding Amount
$407,402.00
Summary
Iron overload and anaemia are two of the most significant health problems affecting humans. Understanding how the body regulates iron levels is key to our understanding of these disorders and to the future development of new therapies. This research is aimed at understanding how a hormone produced in the liver called hepcidin that maintains iron balance is regulated. This research may lead to novel therapies aimed at correcting the iron balance in conditions of iron overload or anaemia.
Innate Immune Signalling In Mycobacterium Tuberculosis Infection
Funder
National Health and Medical Research Council
Funding Amount
$562,857.00
Summary
Tuberculosis (TB) is a major global health threat that causes 1.5 million deaths every year. This study will characterise a new molecular control mechanism that optimises the immune response to the bacteria that cause TB and determine how it contributes to controlling the infection. Such knowledge is essential to help improve patient management and develop better treatments for this devastating disease.
Bulk Mg based hydrogen storage alloys with faster activation. Bulk Mg based hydrogen storage alloys with faster activation. This project aims to improve the performance and efficiency of manufacture of magnesium-based hydrogen storage alloys, making them more cost competitive and widely useable. A hydrogen economy will reduce greenhouse gas emissions and improve air quality in urban areas. The expected outcomes are an understanding of the mechanisms governing the activation process, a necessary ....Bulk Mg based hydrogen storage alloys with faster activation. Bulk Mg based hydrogen storage alloys with faster activation. This project aims to improve the performance and efficiency of manufacture of magnesium-based hydrogen storage alloys, making them more cost competitive and widely useable. A hydrogen economy will reduce greenhouse gas emissions and improve air quality in urban areas. The expected outcomes are an understanding of the mechanisms governing the activation process, a necessary step in manufacture, and techniques to exploit these mechanisms to minimise the activation time. This is expected to develop competitive, bulk magnesium-based hydrogen storage alloys for effective and safe hydrogen storage systems.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC200100023
Funder
Australian Research Council
Funding Amount
$4,920,490.00
Summary
ARC Training Centre for The Global Hydrogen Economy. The centre aims to transform Australia into a hydrogen powerhouse by building enabling capacity in hydrogen innovation in a short timeframe. Australia is well-positioned to capitalise on the emerging global growth of hydrogen, however to be competitive and produce at scale, we need cost-effective hydrogen technologies and capabilities for transitioning hydrogen into industries. This innovative, five-year program will generate new technologies ....ARC Training Centre for The Global Hydrogen Economy. The centre aims to transform Australia into a hydrogen powerhouse by building enabling capacity in hydrogen innovation in a short timeframe. Australia is well-positioned to capitalise on the emerging global growth of hydrogen, however to be competitive and produce at scale, we need cost-effective hydrogen technologies and capabilities for transitioning hydrogen into industries. This innovative, five-year program will generate new technologies and equip a future workforce of industry-focused engineers with advanced skills for development and scaling-up of hydrogen generation and transport. Benefits include: export of hydrogen fuel and advanced technologies; job creation; and a lower emissions domestic energy industry.Read moreRead less
General systems modelling of hydrogen production network in Australia. The project aims at further developing a general framework for systems modelling and applying the framework to investigate the feasibility and sustainability of large-scale hydrogen production in Australia. Two pathways proposed in this project are to be examined: 1) hybrid plants sourcing hydrogen from fossil fuels and solar thermal energy and 2) hydrogen production network producing hydrogen from 100% renewable energy. The ....General systems modelling of hydrogen production network in Australia. The project aims at further developing a general framework for systems modelling and applying the framework to investigate the feasibility and sustainability of large-scale hydrogen production in Australia. Two pathways proposed in this project are to be examined: 1) hybrid plants sourcing hydrogen from fossil fuels and solar thermal energy and 2) hydrogen production network producing hydrogen from 100% renewable energy. The project involves building systems models and using these models to determine optimal operational parameters and conditions with the goal of maintaining export of high-end energy resources to Japan and other countries as well as using hydrogen domestically while minimising the environment effects of hydrogen production.Read moreRead less
Nonlinear Econometric Modelling: A Complex Systems Perspective. It is becoming increasingly accepted that economic systems are both complex and adaptive. However, this introduces a range of problems in constructing, estimating and testing economic models using time series data. In this project, this problem will be addressed through the formulation and implementation of a new methodology and associated techniques. These techniques will allow a researcher to use information obtained from a set o ....Nonlinear Econometric Modelling: A Complex Systems Perspective. It is becoming increasingly accepted that economic systems are both complex and adaptive. However, this introduces a range of problems in constructing, estimating and testing economic models using time series data. In this project, this problem will be addressed through the formulation and implementation of a new methodology and associated techniques. These techniques will allow a researcher to use information obtained from a set of nonlinearity tests to determine which type of nonlinear model provides the best representation of a data generating mechanism. Selected high frequency financial and macroeconomic data (for the US and Australia) will be used in the study. This research is intended to change the direction and emphasis of econometric modelling and promises to have a fundamental impact on forecasting and policy evaluation methods.
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A new photoelectrochemical system for solar hydrogen and electricity. This project aims to develop a new integrated photoelectrochemical (PEC) system for converting solar energy into hydrogen and electricity simultaneously. The key concept is to design innovative advanced materials which will be integrated into PEC devices with capacitor function for both solar fuel production and electricity storage. This project expects to generate new knowledge in understanding the fundamental mechanism of de ....A new photoelectrochemical system for solar hydrogen and electricity. This project aims to develop a new integrated photoelectrochemical (PEC) system for converting solar energy into hydrogen and electricity simultaneously. The key concept is to design innovative advanced materials which will be integrated into PEC devices with capacitor function for both solar fuel production and electricity storage. This project expects to generate new knowledge in understanding the fundamental mechanism of developing functional materials for more efficient solar energy conversion and storage. Expected outcomes include prototypes of the next generation advanced materials and technologies for sustainable energy utilisation systems for converting solar energy into hydrogen and electricity.Read moreRead less
Networked control for distributed renewable energy systems integration. The project aims to develop novel networked and coordinated control methods that greatly increase the capacity of the existing Australian power networks to host growing amounts of roof-top photovoltaic (PV) generation and customer load. These methods reduce the current need for high levels of continuing capital investments by optimally managing the existing network assets to fully exploit the inherent capabilities of PV inve ....Networked control for distributed renewable energy systems integration. The project aims to develop novel networked and coordinated control methods that greatly increase the capacity of the existing Australian power networks to host growing amounts of roof-top photovoltaic (PV) generation and customer load. These methods reduce the current need for high levels of continuing capital investments by optimally managing the existing network assets to fully exploit the inherent capabilities of PV inverters and new distributed battery storages that are now appearing at the domestic and network level. The project plans to combine robust networked control with stochastic optimisation methods to extract the best value from existing and new assets, while improving the load and generation hosting capability, for a given level of reliability.Read moreRead less
Perovskite Materials: Exploring properties beyond solar cells. This project aims to explore functionalities of metal halide perovskite materials for sustainable solar energy conversion and storage, beyond the heavily studied perovskite solar cell application. The project intends to design toxic lead free/less perovskite materials for an integrated photoelectrochemical hydrogen production and solar rechargeable battery system. It will study the relations between material synthesis conditions, dev ....Perovskite Materials: Exploring properties beyond solar cells. This project aims to explore functionalities of metal halide perovskite materials for sustainable solar energy conversion and storage, beyond the heavily studied perovskite solar cell application. The project intends to design toxic lead free/less perovskite materials for an integrated photoelectrochemical hydrogen production and solar rechargeable battery system. It will study the relations between material synthesis conditions, device structure and performance of the photoelectrochemical system. Expected outcomes are low cost and more efficient solar-to-hydrogen conversion and solar energy storage devices, important for sustainable use of intermittent solar energy.Read moreRead less
Towards high efficiency biofuel systems: a molecular resolution three-dimensional atlas of the photosynthetic machinery of a high-efficiency green algae cell. Solar-powered single-cell green-algae systems represent a powerful and environmentally friendly biotechnology used to produce clean fuels, food and high value products. This project is focused on solving the three-dimensional structure of key components of the photosynthetic machinery to improve the efficiency and profitability of advance ....Towards high efficiency biofuel systems: a molecular resolution three-dimensional atlas of the photosynthetic machinery of a high-efficiency green algae cell. Solar-powered single-cell green-algae systems represent a powerful and environmentally friendly biotechnology used to produce clean fuels, food and high value products. This project is focused on solving the three-dimensional structure of key components of the photosynthetic machinery to improve the efficiency and profitability of advance microalgae production systems.Read moreRead less