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Research Topic : Cell Signalling
Australian State/Territory : TAS
Australian State/Territory : SA
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  • Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100183

    Funder
    Australian Research Council
    Funding Amount
    $950,000.00
    Summary
    Protein Quantitation Centre of South Australia renewal for Systems Biology. This application aims to renew Mass Spectrometry (MS) instrumentation to characterise and quantify Biomolecules towards a better understanding of biological processes. UniSA, Uni Adelaide, Flinders have established the Protein Quantitation Centre of South Australia (PQCSA) in 2013 through an ARC LIEF lead by CI Hoffmann and this application will renew and expand MS capacity towards metabolites, glycans and lipids. This .... Protein Quantitation Centre of South Australia renewal for Systems Biology. This application aims to renew Mass Spectrometry (MS) instrumentation to characterise and quantify Biomolecules towards a better understanding of biological processes. UniSA, Uni Adelaide, Flinders have established the Protein Quantitation Centre of South Australia (PQCSA) in 2013 through an ARC LIEF lead by CI Hoffmann and this application will renew and expand MS capacity towards metabolites, glycans and lipids. This will enable researchers in South Australia to work towards a full understanding of biological processes and towards expanding their knowledge to Systems Biology. Expected outcome of the projects are multiple interdisciplinary collaborations between the CI's and should provide significant benefits in research outputs.
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    Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100155

    Funder
    Australian Research Council
    Funding Amount
    $909,079.00
    Summary
    Advancing 4D fluorescence microscopy within Australia. This multi-institutional proposal aims to establish a state-of-the-art Lightsheet microscope facility in South Australia with enhanced analysis infrastructure and a national user support network. Expectations are, this will transform researcher outcomes for multiple disciplines by facilitating high-resolution four-dimensional interrogation of novel biological processes. Significant benefits will include the ability to image deep within livin .... Advancing 4D fluorescence microscopy within Australia. This multi-institutional proposal aims to establish a state-of-the-art Lightsheet microscope facility in South Australia with enhanced analysis infrastructure and a national user support network. Expectations are, this will transform researcher outcomes for multiple disciplines by facilitating high-resolution four-dimensional interrogation of novel biological processes. Significant benefits will include the ability to image deep within living tissue over long time-scales without inducing phytotoxicity to produce high-impact fundamental and translatable outcomes, the development of novel probes and methodologies, new cross-disciplinary collaborations, and new and unique funding, student training and public engagement opportunities.
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    Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100174

    Funder
    Australian Research Council
    Funding Amount
    $380,000.00
    Summary
    Development of a digital Transmission Electron Microscope Facility in Tasmania. Development of a digital transmission electron microscope facility: Transmission electron microscopy is a fundamental tool for the study of biological systems at the ultrastructural level. This project will establish a facility that will be accessible to a range of biological researchers, replacing aged and non-sustainable electron microscopy facilities. The instrument will revitalise cellular research and provide ad .... Development of a digital Transmission Electron Microscope Facility in Tasmania. Development of a digital transmission electron microscope facility: Transmission electron microscopy is a fundamental tool for the study of biological systems at the ultrastructural level. This project will establish a facility that will be accessible to a range of biological researchers, replacing aged and non-sustainable electron microscopy facilities. The instrument will revitalise cellular research and provide additional insights and outcomes related to the study of intracellular features in a diverse range of systems and models. This will add substantially to the knowledge base across a wide range of fields of research, increasing national contributions in the areas of neuroscience, separation science and marine science.
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    Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100075

    Funder
    Australian Research Council
    Funding Amount
    $315,000.00
    Summary
    Acoustic liquid handling robotics for bioactive compound discovery. This project aims to use a Labcyte Echo 550 acoustic dispenser with Combination Software to deliver sophisticated assay-ready screening. The Echo is the only liquid handling dispenser for 1536-well microplates and will allow Australian researchers to develop assay miniaturisation. The robotics will provide our nation’s researchers with a distinct competitive edge by enhancing assay sophistication, accuracy and reproducibility wh .... Acoustic liquid handling robotics for bioactive compound discovery. This project aims to use a Labcyte Echo 550 acoustic dispenser with Combination Software to deliver sophisticated assay-ready screening. The Echo is the only liquid handling dispenser for 1536-well microplates and will allow Australian researchers to develop assay miniaturisation. The robotics will provide our nation’s researchers with a distinct competitive edge by enhancing assay sophistication, accuracy and reproducibility while reducing cost. The expected benefits will advance the elucidation of molecular mechanisms involved in complex biological phenomena. The benefits of this are substantial, including reduction in test compound and reagents, which in turn reduces laboratory costs, conserves cells and increases data quality.
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