An X-ray crystallographic investigation into co-receptors on T-lymphocytes. T lymphocytes are an indispensable cellular component of the immune system. The normal process of T cell selection in the thymus, and the ability of mature T cells to respond to foreign antigens are governed by receptor recognition and co-receptor mediated events. The co-receptors encompass a wide spectrum of structurally diverse proteins that are involved in adhesion, co-ligation and signal transduction. This proposa ....An X-ray crystallographic investigation into co-receptors on T-lymphocytes. T lymphocytes are an indispensable cellular component of the immune system. The normal process of T cell selection in the thymus, and the ability of mature T cells to respond to foreign antigens are governed by receptor recognition and co-receptor mediated events. The co-receptors encompass a wide spectrum of structurally diverse proteins that are involved in adhesion, co-ligation and signal transduction. This proposal aims to investigate, using X-ray crystallography as the primary research tool, co- receptors located on T-lymphocytes. This work will gain fundamental insights into co-receptor function.Read moreRead less
Protein modifications in plant mitochondria: towards functional proteomics. Energy production within plants in cellular structures called mitochondria is vital for their growth and development and is central to the early success of germinating and growing seedlings. This project intends to analyse mitochondria within plants using state of the art instrumentation and technologies. The findings from this research have the potential to directly flow into the plant biotechnology industry and could a ....Protein modifications in plant mitochondria: towards functional proteomics. Energy production within plants in cellular structures called mitochondria is vital for their growth and development and is central to the early success of germinating and growing seedlings. This project intends to analyse mitochondria within plants using state of the art instrumentation and technologies. The findings from this research have the potential to directly flow into the plant biotechnology industry and could assist the future development of Australian agriculture through genetic improvements. The expertise developed by this work will ensure that Australia is well placed to exploit future advances in this field and to further generate the development of novel biotechnological applications in agriculture.Read moreRead less
Special Research Initiatives - Grant ID: SR0354715
Funder
Australian Research Council
Funding Amount
$40,000.00
Summary
The Australian Plant Nutriomics Network. The Australian Plant Nutriomics Network will link Australian scientists investigating aspects of the plant nutriome - the summation of processes that deliver nutrients and water from soil to plants. The network will establish a coordinated approach to understanding genes, proteins and metabolites involved in element acquisition and how their functions are linked to soil conditions to maximise food quality and overcome soil environmental challenges. Inter ....The Australian Plant Nutriomics Network. The Australian Plant Nutriomics Network will link Australian scientists investigating aspects of the plant nutriome - the summation of processes that deliver nutrients and water from soil to plants. The network will establish a coordinated approach to understanding genes, proteins and metabolites involved in element acquisition and how their functions are linked to soil conditions to maximise food quality and overcome soil environmental challenges. International articulation will ensure information exchange and enhance postgraduate and postdoctoral training by reciprocal visits and focused workshops. A major goal will be a strategy to integrate research using a complex systems approach to problems.Read moreRead less