In touch with the environment: dissecting early tactile responses in plants. This project aims to identify the regulatory mechanisms that control touch-responses in plants. Although plants cannot relocate in the face of danger, they are able to sense mechanical manipulations from the environment. These could be caused by pathogens, herbivores, rain or even wind. This touch-responsiveness of plants is essential for pathogen resistance and for triggering architectural changes to overcome obstacles ....In touch with the environment: dissecting early tactile responses in plants. This project aims to identify the regulatory mechanisms that control touch-responses in plants. Although plants cannot relocate in the face of danger, they are able to sense mechanical manipulations from the environment. These could be caused by pathogens, herbivores, rain or even wind. This touch-responsiveness of plants is essential for pathogen resistance and for triggering architectural changes to overcome obstacles and prevent mechanical damage. Using a comprehensive tool set of genetics, genomics and proteomics, this project aims to identify the upstream regulators that control touch responses. Furthermore, it is expected to expand our understanding of the physiological impacts of touch-responses on growth and stress tolerance.Read moreRead less
Investigating The Cellular Response To Iron-Depletion: The Trilogy Of ASK1, Thioredoxin And Ribonucleotide Reductase
Funder
National Health and Medical Research Council
Funding Amount
$552,572.00
Summary
Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for t ....Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.Read moreRead less
Cooperative control of networked systems with constraints. This project aims to address the challenge of networked systems in deploying teams of robotic agents. Control of the networked system is extremely difficult due to real world constraints imposed on each agent. This project will focus on motion constraints, equipment/capability constraints, and spatial constraints. In addition to theoretical advances, the wider scientific community will benefit directly, because the control algorithms dev ....Cooperative control of networked systems with constraints. This project aims to address the challenge of networked systems in deploying teams of robotic agents. Control of the networked system is extremely difficult due to real world constraints imposed on each agent. This project will focus on motion constraints, equipment/capability constraints, and spatial constraints. In addition to theoretical advances, the wider scientific community will benefit directly, because the control algorithms developed are expected to allow straightforward deployment of robotic teams. There are myriad applications for cooperative robotic agents, ranging from surveillance, to environmental monitoring using underwater and aerial drone formations – with an array of benefits and impacts including economic, commercial and societal. The results are intended to ensure and cement Australia’s front-line position in the current technological revolution known as “Industry 4.0”.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
TELEPHONE COUNSELLING FOR MAINTENANCE OF PHYSICAL ACTIVITY, WEIGHT LOSS And GLYCAEMIC CONTROL IN TYPE 2 DIABETES
Funder
National Health and Medical Research Council
Funding Amount
$1,285,894.00
Summary
Regular exercise, a healthy diet and weight loss are key to managing type 2 diabetes, yet these are major challenges for most people with diabetes. This study will evaluate the impact of a telephone counselling program to assist people with type 2 diabetes to exercise, eat a healthy diet and lose weight, with the goal of helping them to sustain these changes over the long-term. It is expected that these lifestyle changes will also result in improved blood glucose control and quality of life.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561229
Funder
Australian Research Council
Funding Amount
$518,427.00
Summary
Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at V ....Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at Victoria University for the development of communication and endoscopic technology. The instrument design will allow multiple use of the lightsource and choice of specific imaging devices (microscopes) to ensure that applications in biocellular imaging, intravital microscopy and fiber optic design and imaging are individually optimised.Read moreRead less
Proteome mapping of the model fungal plant pathogen Stagonospora nodorum using LC-LC-MS/MS. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum in Australia. This project aims to identify the proteins produced by Stagonospora nodorum through the development of a new proteomics technique. Two clear benefits to the community resulting from this project will emerge. The first will be the expert ....Proteome mapping of the model fungal plant pathogen Stagonospora nodorum using LC-LC-MS/MS. Stagonospora nodorum is a fungus that causes leaf and glume blotch disease on wheat. This disease alone causes $55 million dollars in yield losses per annum in Australia. This project aims to identify the proteins produced by Stagonospora nodorum through the development of a new proteomics technique. Two clear benefits to the community resulting from this project will emerge. The first will be the expert training of a student in proteomics, a skill that is keenly sought. Secondly, the identification of these pathogen proteins will lead to new strategies to better control the disease and secure the supply of wheat.Read moreRead less
Control and Optimization of Distributed Multiagent Formations. The project aims to develop a conceptual framework and algorithms for handling multi-vehicle formation control. Formations of unmanned airborne vehicles are currently used by defence forces and swarms of micro-vehicles are beginning to find increasing use in defence and for civilian emergency response, largely for surveillance purposes. Vehicles must cooperate to achieve a global formation objective, while respecting constraints on s ....Control and Optimization of Distributed Multiagent Formations. The project aims to develop a conceptual framework and algorithms for handling multi-vehicle formation control. Formations of unmanned airborne vehicles are currently used by defence forces and swarms of micro-vehicles are beginning to find increasing use in defence and for civilian emergency response, largely for surveillance purposes. Vehicles must cooperate to achieve a global formation objective, while respecting constraints on sensors, energy, and general mechanical limitations. The project aims to resolve the challenges of deciding what a single vehicle should observe, what and to where it should communicate, and how it should move in relation to what it sees. The conceptual framework developed may also be relevant in guiding future defence acquisitions and civilian applications.Read moreRead less
What drives parasite spread through social networks: lessons from lizards. Australia's biodiversity is continually threatened by new epidemics of local and foreign diseases and parasites. This project will enhance our understanding of how these diseases spread, allowing more effective controls to be developed to protect wildlife species, animal populations and, ultimately, Australian ecosystems.