Elucidating the molecular basis of plant potyvirus resistance . Plant viruses are responsible for a large proportion of crop losses, and genetic resistance is currently the most effective means to control viral spread. This project investigates, on a molecular and structural level, host factors that plant viruses hijack during infection, and in particular, the mutations in these factors that confer resistance. We further aim to elucidate the mechanisms by which plant viruses overcome resistance ....Elucidating the molecular basis of plant potyvirus resistance . Plant viruses are responsible for a large proportion of crop losses, and genetic resistance is currently the most effective means to control viral spread. This project investigates, on a molecular and structural level, host factors that plant viruses hijack during infection, and in particular, the mutations in these factors that confer resistance. We further aim to elucidate the mechanisms by which plant viruses overcome resistance mediated by these host factors. A detailed understanding of the molecular interactions between plant viruses and their host will enable new, robust and more effective forms of resistance to be engineered. This work therefore has economic and environmental implications for agricultural productivity in Australia. Read moreRead less
ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology indust ....ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology industry, the protection of the Australian Environment and the well-being of the Australian people. Key issues for this Centre include testicular cancer, male infertility, contraception, pest animal control, environmental impacts on human health and gene pharming.Read moreRead less
Identifying novel insecticides and their targets: probing Australian arachnid venoms. Insect pests destroy an estimated 2-3 billion dollars of crops in Australia. Insect pests also are responsible for the transmission of many new and re-emerging human, animal and plant diseases threatening health, wellbeing and prosperity. Current insecticides are severely limited by toxicity and/or insect resistance, and some are undergoing use cancellation overseas. Thus there is an urgent need to develop safe ....Identifying novel insecticides and their targets: probing Australian arachnid venoms. Insect pests destroy an estimated 2-3 billion dollars of crops in Australia. Insect pests also are responsible for the transmission of many new and re-emerging human, animal and plant diseases threatening health, wellbeing and prosperity. Current insecticides are severely limited by toxicity and/or insect resistance, and some are undergoing use cancellation overseas. Thus there is an urgent need to develop safer and more specific insecticides that are effective against disease vectors and agricultural pest insects, as well as to identify new insecticide targets. This research has a multi-million dollar potential benefit to agricultural, health and pest control sectorsRead moreRead less
REACH: Researching Effective Approaches To Cleaning In Hospitals
Funder
National Health and Medical Research Council
Funding Amount
$657,862.00
Summary
Healthcare associated infections are a major challenge for hospitals. Infections can spread via the patient environment, because colonized patients and staff can contaminate surfaces and equipment with micro-organisms. Cleaning is a vital component of patient care, but is a complex process with little real evidence to inform practice. This project will take a targeted approach to improving hospital cleaning to reduce infection rates; and examine the cost-effectiveness of this approach.
Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hard ....Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hardware, software and communication systems to dynamically generate decision tools for safe and efficient power system operating conditions. These systems will also generate alarms if any risky operational situations arise.Read moreRead less
Safety in the Heavy Vehicle Industry: A Collaborative Response. The management and regulation of heavy vehicles, particularly in relation to safety, is recognised as an urgent issue at all levels of government across Australia. In the absence of research that identifies the key determinants of heavy vehicle crashes, countermeasures will continue to be based on anecdote. The proposed study will determine the role key risk factors, namely scheduling and sleep-related factors, play in heavy vehicl ....Safety in the Heavy Vehicle Industry: A Collaborative Response. The management and regulation of heavy vehicles, particularly in relation to safety, is recognised as an urgent issue at all levels of government across Australia. In the absence of research that identifies the key determinants of heavy vehicle crashes, countermeasures will continue to be based on anecdote. The proposed study will determine the role key risk factors, namely scheduling and sleep-related factors, play in heavy vehicle crashes and will identify cost-effective strategies to reduce the growing economic burden associated with these crashes.Read moreRead less
ARC Centre for Complex Dynamic Systems & Control. Complex dynamic systems are an inescapable feature of the world we live in. Modelling, analysing and optimizing complex behaviour is crucial for environment, process industry, biomedical, energy distribution, transportation and other applications. The Centre for Complex Dynamic Systems and Control will become an international authority in the analysis, design and optimization of complex dynamic systems, pursuing both outstanding fundamental and c ....ARC Centre for Complex Dynamic Systems & Control. Complex dynamic systems are an inescapable feature of the world we live in. Modelling, analysing and optimizing complex behaviour is crucial for environment, process industry, biomedical, energy distribution, transportation and other applications. The Centre for Complex Dynamic Systems and Control will become an international authority in the analysis, design and optimization of complex dynamic systems, pursuing both outstanding fundamental and cutting edge applied research outcomes. These outcomes will be of specific benefit to partner organizations including minerals, process, metal forming, and automotive industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100121
Funder
Australian Research Council
Funding Amount
$384,671.00
Summary
Genomic library infrastructure for ancient environmental samples. This project aims to enable automated genome recovery from diverse environmental samples, without contamination risk. For more than 100 years, environmental scientists have studied diverse organism / environment interactions using a variety of conceptual and technical tools. Recently, studies of ancient and historical DNA have come to complement these tools and to occupy a significant place in environmental studies conducted over ....Genomic library infrastructure for ancient environmental samples. This project aims to enable automated genome recovery from diverse environmental samples, without contamination risk. For more than 100 years, environmental scientists have studied diverse organism / environment interactions using a variety of conceptual and technical tools. Recently, studies of ancient and historical DNA have come to complement these tools and to occupy a significant place in environmental studies conducted over serial time. The project’s addition to the existing dual Ancient DNA complex facility at Griffith University will comprise two liquid handling workstations, each being housed in separate, self-contained, ancient DNA laboratories. The new facility will enable many researchers to have unprecedented access to an ancient DNA facility and a high level of technical support.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882357
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering ....A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering/purifying water and gases. The dedicated computing facility will enable a fast interactive cycle between simulation and experiment in these areas, accelerating the pace of research and applications.Read moreRead less