Control and learning for enhancing capabilities of quantum sensors. This project aims to develop new theories and algorithms to enhance capabilities in engineering quantum sensors from the perspective of systems and control. The project is significant because it is anticipated to advance key knowledge and provide systematic methods to enable achievement of high-precision sensing for wide applications, e.g., early disease detection, medical research, discovery of ore deposits and groundwater moni ....Control and learning for enhancing capabilities of quantum sensors. This project aims to develop new theories and algorithms to enhance capabilities in engineering quantum sensors from the perspective of systems and control. The project is significant because it is anticipated to advance key knowledge and provide systematic methods to enable achievement of high-precision sensing for wide applications, e.g., early disease detection, medical research, discovery of ore deposits and groundwater monitoring. The intended outcomes are fundamental theories, effective control and learning algorithms for achieving highly-sensitive sensors. These outcomes should make important contributions to and deliver new knowledge and skills for Australia's sensing industries, which could benefit Australia's economic growth.Read moreRead less
Role of Musashi in the regulation of cell cycle proteins. We have identified a protein family that directs cell fate and maintains male fertility. This project will provide new avenues for generation of contraceptives in male animals and to regulate stem cells for production of specialised cell types in biotechnological applications.
New quantum and robust control theory with applications to quantum optics. The application of quantum mechanics to the creation of quantum technology promises to be one of the most exciting technological developments of this century. Possible applications of quantum technologies include vastly improved sensors to search for minerals or gravity waves, secure quantum cryptography, and quantum computing. Quantum feedback control is a key tool in quantum technology. This project will lay the fou ....New quantum and robust control theory with applications to quantum optics. The application of quantum mechanics to the creation of quantum technology promises to be one of the most exciting technological developments of this century. Possible applications of quantum technologies include vastly improved sensors to search for minerals or gravity waves, secure quantum cryptography, and quantum computing. Quantum feedback control is a key tool in quantum technology. This project will lay the foundations of systematic theories of robust, coherent and nonlinear quantum feedback control and lead to advances in the control of highly resonant systems which underlie experimental quantum and nano technology. This will enable Australia to reap great benefits as this new technological area emerges.Read moreRead less
ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology indust ....ARC Centre of Excellence in Biotechnology and Development. The Centre will create a multidisciplinary research team focusing on the molecular mechanisms that drive the specification and differentiation of male germ cells. This research will improve our fundamental understanding of how complex regulatory networks control the expression of a complex phenotype, the spermatozoon. It will also create a platform of knowledge from which we can stimulate the growth of the Australian Biotechnology industry, the protection of the Australian Environment and the well-being of the Australian people. Key issues for this Centre include testicular cancer, male infertility, contraception, pest animal control, environmental impacts on human health and gene pharming.Read moreRead less
Investigating The Cellular Response To Iron-Depletion: The Trilogy Of ASK1, Thioredoxin And Ribonucleotide Reductase
Funder
National Health and Medical Research Council
Funding Amount
$552,572.00
Summary
Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for t ....Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.Read moreRead less
Control of network systems with signed dynamical interconnections. New technologies such as online recommendations, smart grids, and cyber-physical systems are becoming backbone infrastructure. Such systems are operated as network systems with interconnected functioning units (agents) where cooperative and adversarial agent relations often coexist. This project aims to develop the theories and tools for designing and building dynamic networks with signed interactions that arise from a variety of ....Control of network systems with signed dynamical interconnections. New technologies such as online recommendations, smart grids, and cyber-physical systems are becoming backbone infrastructure. Such systems are operated as network systems with interconnected functioning units (agents) where cooperative and adversarial agent relations often coexist. This project aims to develop the theories and tools for designing and building dynamic networks with signed interactions that arise from a variety of applications where both cooperative and adversarial agent interactions coexist. By developing theories and algorithms for control and identification over such systems, this project will contribute directly to their safe and robust operation. The resulting theories will provide deeper understanding of network control systems and the resulting algorithms will enable the elimination of attackers and malicious users for online review systems and smart grids. This project will contribute to increased cybersecurity for all Australians.Read moreRead less
Generalised Energy Based Robust and Nonlinear Control Systems. This project aims to develop new energy-based theories of robust stability analysis and controller design for both linear and nonlinear systems, building on passivity and negative imaginary system theories and their physical interpretations along with stochastic optimal control theory. These control theories would allow for a wide range of plant dynamics in the design of high-performance robust control systems, enabling advances in e ....Generalised Energy Based Robust and Nonlinear Control Systems. This project aims to develop new energy-based theories of robust stability analysis and controller design for both linear and nonlinear systems, building on passivity and negative imaginary system theories and their physical interpretations along with stochastic optimal control theory. These control theories would allow for a wide range of plant dynamics in the design of high-performance robust control systems, enabling advances in emerging technologies including nanopositioning, micro-electromechanical systems and opto-mechatronics. The project plans to combine these theoretical advances with numerical methods involving advanced optimisation tools and the experimental implementation of nanopositioning control systems in atomic force microscopy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453295
Funder
Australian Research Council
Funding Amount
$369,697.00
Summary
NMR cryosystem for structural and functional biology. State-of-the-art hardware is requested for the 600-MHz NMR spectrometers situated at University of Sydney and UNSW. A cryosystem installed at USyd. will provide a massive boost in productivity and will allow projects previously inaccessible due to excessive turn-around times, or sensitivity or solubility problems to become tractable. This system will provide new opportunities to researchers from USyd., UNSW and ANU, but will restrict the ver ....NMR cryosystem for structural and functional biology. State-of-the-art hardware is requested for the 600-MHz NMR spectrometers situated at University of Sydney and UNSW. A cryosystem installed at USyd. will provide a massive boost in productivity and will allow projects previously inaccessible due to excessive turn-around times, or sensitivity or solubility problems to become tractable. This system will provide new opportunities to researchers from USyd., UNSW and ANU, but will restrict the versatility of the USyd. instrument. The installation of a TBI probe at UNSW will counter this, and provide a REAL network of NMR instruments across NSW and the ACT.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less